anti-Ankyrin Repeat-Containing Protein (EHMT2) Antibodies

A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. Additionally we are shipping EHMT2 Proteins (7) and EHMT2 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EHMT2 10919 Q96KQ7
EHMT2 110147 Q9Z148
EHMT2 361798  
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Top anti-EHMT2 Antibodies at antibodies-online.com

Showing 10 out of 60 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated ChIP, WB Quiescent human colon carcinoma HCT116 cultures were treated with 10 % FBS for three time points (0, 15, 30min) or (0, 30, 60min) were used in Matrix-ChIP and real-time PCR assays at EGR1 gene (Exon1) and 15kb upstream site. 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP, WB Western Blot: EHMT2 Antibody [ABIN2515095] - Whole cell lysate (15 and 50 ug) from HeLa cells. Antibody used for WB at 1 ug/ml. 100 μL Log in to see 7 to 9 Days
$556.31
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: EHMT2 Antibody [NBP2-13948] - Staining of human esophagus shows moderate nuclear positivity in squamous epithelial cells. Immunocytochemistry/Immunofluorescence: EHMT2 Antibody [NBP2-13948] - Staining of human cell line MCF-7 shows positivity in nucleus and cytoskeleton (intermediate filaments), but not nucleoli. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated IHC, WB 100 μg Log in to see 2 to 3 Days
$335.00
Details
Human Rabbit Un-conjugated FACS, WB EHMT2 Antibody (N-term) (ABIN651717) western blot analysis in Jurkat cell line lysates (15 µg/lane). This demonstrates the EHMT2 antibody detected the EHMT2 protein (arrow). EHMT2 Antibody (N-term) (ABIN651717) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Hamster Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$346.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 16 Days
$476.15
Details
Dog Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated WB   200 μg Log in to see 7 to 9 Days
$1,057.83
Details
Human Rabbit Un-conjugated IF, WB   100 μL Log in to see 7 to 9 Days
$771.83
Details

EHMT2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-EHMT2 Antibodies

  1. Human Polyclonal EHMT2 Primary Antibody for ICC, IF - ABIN251509 : Cho, Kelly, Hayami, Toyokawa, Takawa, Yoshimatsu, Tsunoda, Field, Neal, Ponder, Nakamura, Hamamoto: Enhanced expression of EHMT2 is involved in the proliferation of cancer cells through negative regulation of SIAH1. in Neoplasia (New York, N.Y.) 2011 (PubMed)
    Show all 2 Pubmed References

  2. Cow (Bovine) Polyclonal EHMT2 Primary Antibody for ChIP, WB - ABIN2779680 : Kondo, Shen, Ahmed, Boumber, Sekido, Haddad, Issa: Downregulation of histone H3 lysine 9 methyltransferase G9a induces centrosome disruption and chromosome instability in cancer cells. in PLoS ONE 2008 (PubMed)

  3. Human Polyclonal EHMT2 Primary Antibody for ICC, IF - ABIN4313049 : Mauger, Klinck, Chabot, Muchardt, Allemand, Batsché: Alternative splicing regulates the expression of G9A and SUV39H2 methyltransferases, and dramatically changes SUV39H2 functions. in Nucleic acids research 2015 (PubMed)

More Antibodies against EHMT2 Interaction Partners

Human Ankyrin Repeat-Containing Protein (EHMT2) interaction partners

  1. Regulated methylation and phosphorylation serve as a switch controlling G9a and GLP (show RCBTB1 Antibodies) coactivator function, suggesting that this mechanism may be a general paradigm for directing specific transcription factor and coregulator actions on different genes.

  2. interleukin-8 (show IL8 Antibodies) is a downstream effector of G9a to increase gemcitabine resistance in pancreatic cancer. Overexpression of G9a correlated with poor survival and early recurrence in pancreatic cancer patients.

  3. Taken together, our findings provide evidence that G9a protects head and neck squamous cell carcinomas (HNSCC)cells against chemotherapy by increasing the synthesis of GSH, and imply G9a as a promising target for overcoming cisplatin resistance in HNSCC

  4. In this study, EHMT2 (a histone methyltransferase) was determined to be significantly overexpressed in breast cancer tissues and in Oncomine data. In addition, knockdown of EHMT2 reduced cell migration and invasion.

  5. Knockdown of G9a increased the sensitivity of cells to radiation treatment and sensitized cells to DNA damage agents through PP2A-RPA axis.

  6. EHMT2 can directly repress Beclin-1 (show BECN1 Antibodies) and the inhibition of EHMT2 may be a useful therapeutic approach for cancer prevention by activating autophagy

  7. IFNgamma induced PPAR gamma coactivator-1 alpha (PGC-1alpha) positively regulated RIG-I; with PRMT-1 and G9a affecting PGC-1alpha in a counter-regulatory manner.

  8. Loss of miR-1 (show FSD1 Antibodies) and gene copy number gain of G9a contributed to its frequent upregulation in liver cancer, which epigenetically silenced the expression of tumor suppressor RARRES3 (show RARRES3 Antibodies), and ultimately contributed to hepatocellular carcinoma (HCC (show FAM126A Antibodies)) cell proliferation and migration.

  9. G9a promotes breast cancer by regulating iron metabolism through the repression of ferroxidase (show CP Antibodies) hephaestin (show HEPH Antibodies).

  10. study uncovers a novel mechanism of G9A promoting tumor cell growth and invasion by silencing CASP1 (show CASP1 Antibodies), and implies that G9A may serve as a therapeutic target in treating Non-small-cell lung cancer.

Arabidopsis thaliana Ankyrin Repeat-Containing Protein (EHMT2) interaction partners

  1. These results suggest that PIA2 modulates phyA-mediated PIF3 phosphorylation by physical interaction with PIF3 and that the secondary structure of the PIA2 N-terminus is important in this modulation.

Mouse (Murine) Ankyrin Repeat-Containing Protein (EHMT2) interaction partners

  1. These results identify G9a-induced histone methylation at the OXT (show OXT Antibodies) and AVP (show AVP Antibodies) promoters in the Basolateral Amygdala as a mechanism for mediating stress-induced lasting behavioral depression and its reversal by exercise.

  2. The findings of this study suggested that G9a participates in the nerve injury-induced reduction of the Oprm1 gene likely through G9a-triggered blockage in the access of cyclic AMP response element binding protein to this gene.

  3. GLP (show GOLGA6A Antibodies)/G9a H3K9 methyltransferase complex is an enzyme counteracting Jmjd1a (show KDM3A Antibodies)-mediated H3K9 demethylation at the Sry (show SRY Antibodies) locus in gonadal somatic cells

  4. G9a regulates cell proliferation and timing of differentiation and that G9a expression in the tooth mesenchyme is required for proper tooth development

  5. Jmjd2c (show KDM4C Antibodies) and G9a are novel enhancer-associated factors. Loss of Jmjd2c (show KDM4C Antibodies) abrogates G9a recruitment and further destabilises loading of the mediator and cohesin components Med1 (show MBD4 Antibodies) and Smc1a (show SMC1A Antibodies) at newly activated and poised enhancers in embryonic stem cell-derived epiblast-like cells.

  6. G9a is an important regulator in placental diseases caused by defective vascular maturation.

  7. miR (show MLXIP Antibodies)-217-mediated, genetic, or pharmacological inactivation of EHMT1 (show EHMT1 Antibodies)/2 was sufficient to promote pathological hypertrophy

  8. G9A overexpression is associated with peritoneal fibrosis.

  9. high levels of G9a-dependent H3K9me2 at ILC3-specific genetic loci, demonstrating that G9a-mediated repression of ILC3-associated genes is critical for the optimal development of ILC2s.

  10. G9a functions both as a co-activator and a co-repressor to enhance cellular proliferation and inhibit myogenic differentiation.

Pig (Porcine) Ankyrin Repeat-Containing Protein (EHMT2) interaction partners

  1. EHMT2 inhibitor BIX-01294 is a potent inhibitor of H3K9 dimethylation and transient alterations in global histone modifications can have profound effects on embryo developmental potential.

Cow (Bovine) Ankyrin Repeat-Containing Protein (EHMT2) interaction partners

  1. The data confirm the involvement of EHMT2 in the epigenetic regulation of IFN-b and demonstrate the activation of a general antiviral state after EHMT2 inhibition.

EHMT2 Antigen Profile

Protein Summary

A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. This gene is found near this cluster\; it was mapped near the gene for C2 within a 120-kb region that included a HSP70 gene pair. These genes are all within the human major histocompatibility complex class III region. This gene was thought to be two different genes, NG36 and G9a, adjacent to each other but a recent publication shows that there is only a single gene. The protein encoded by this gene is thought to be involved in intracellular protein-protein interaction. There are three alternatively spliced transcript variants of this gene but only two are fully described.

Gene names and symbols associated with EHMT2

  • euchromatic histone lysine methyltransferase 2 (EHMT2) antibody
  • ankyrin repeat-containing protein (ank1) antibody
  • ankyrin repeat-containing protein (IscW_ISCW006888) antibody
  • ankyrin repeat-containing protein (Arnit_2917) antibody
  • Ankyrin repeat family protein (AT3G04470) antibody
  • Ankyrin repeat family protein (AT4G14390) antibody
  • Ankyrin repeat family protein (AT4G19150) antibody
  • Ankyrin repeat family protein (AT4G03500) antibody
  • Ankyrin repeat family protein (AT4G03450) antibody
  • Ankyrin repeat family protein (AT4G03460) antibody
  • Ankyrin repeat family protein (AT4G03440) antibody
  • Ankyrin repeat family protein (PIA1) antibody
  • Ankyrin repeat family protein (AT5G15500) antibody
  • Ankyrin repeat family protein (AT5G51160) antibody
  • Ankyrin repeat family protein (AT5G54620) antibody
  • Ankyrin repeat family protein (ANK6) antibody
  • Ankyrin repeat family protein (AT1G04780) antibody
  • Ankyrin repeat family protein (AT1G62050) antibody
  • euchromatic histone lysine N-methyltransferase 2 (Ehmt2) antibody
  • euchromatic histone lysine methyltransferase 2 (Ehmt2) antibody
  • Bat8 antibody
  • C6orf30 antibody
  • D17Ertd710e antibody
  • DL3235W antibody
  • F9H3.6 antibody
  • F9H3.7 antibody
  • F9H3.9 antibody
  • F9H3.13 antibody
  • F9H3_6 antibody
  • F9H3_7 antibody
  • F9H3_9 antibody
  • F9H3_13 antibody
  • F13G24.40 antibody
  • FCAALL.188 antibody
  • G9a antibody
  • GAT8 antibody
  • KMT1C antibody
  • MAF19.22 antibody
  • MAF19_22 antibody
  • MRB17.12 antibody
  • MRB17_12 antibody
  • MWD22.10 antibody
  • MWD22_10 antibody
  • Ng36 antibody
  • T18B16.120 antibody
  • T18B16_120 antibody
  • T20K14.110 antibody
  • T20K14_110 antibody
  • T27C4.12 antibody
  • T27C4_12 antibody

Protein level used designations for EHMT2

G9A histone methyltransferase , H3-K9-HMTase 3 , HLA-B associated transcript 8 , HLA-B-associated transcript 8 , ankyrin repeat-containing protein , histone H3-K9 methyltransferase 3 , histone-lysine N-methyltransferase EHMT2 , histone-lysine N-methyltransferase, H3 lysine-9 specific 3 , lysine N-methyltransferase 1C , protein G9a , euchromatic histone-lysine N-methyltransferase 2 , HLA-B associated transcript 8, rat orthologue

GENE ID SPECIES
10919 Homo sapiens
4606933 Azoarcus sp. BH72
8032296 Ixodes scapularis
9173113 Arcobacter nitrofigilis DSM 7299
819603 Arabidopsis thaliana
827084 Arabidopsis thaliana
827653 Arabidopsis thaliana
827731 Arabidopsis thaliana
827913 Arabidopsis thaliana
827916 Arabidopsis thaliana
827920 Arabidopsis thaliana
830677 Arabidopsis thaliana
831403 Arabidopsis thaliana
835190 Arabidopsis thaliana
835551 Arabidopsis thaliana
836244 Arabidopsis thaliana
839414 Arabidopsis thaliana
842501 Arabidopsis thaliana
110147 Mus musculus
361798 Rattus norvegicus
474851 Canis lupus familiaris
100124382 Sus scrofa
100355131 Oryctolagus cuniculus
100728628 Cavia porcellus
100059118 Equus caballus
514062 Bos taurus
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