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ANXA13 encodes a member of the annexin family.
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ANXA13 is associated with colorectal cancer cell invasion in vitro, and with lymph node metastasis and poor survival in colorectal cancer patients
High ANXA13 expression is associated with Refractory Lupus Nephritis.
Ectopic overexpression of Annexin A13 was likewise sufficient to sensitize malignant breast cancer cells to treatment with Rapamycin.
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. The specific function of this gene has not yet been determined\; however, it is associated with the plasma membrane of undifferentiated, proliferating endothelial cells and differentiated villus enterocytes. Alternatively spliced transcript variants encoding different isoforms have been identified.
, annexin, intestine-specific
, intestine-specific annexin
, annexin A6
, ANX XIII
, annexin 13
, annexin XIIIb
, annexin A13