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ANXA2 encodes a member of the annexin family. Additionally we are shipping Annexin A2 Kits (59) and Annexin A2 Proteins (37) and many more products for this protein.
Showing 10 out of 245 products:
Human Polyclonal Annexin A2 Primary Antibody for ICC, IF - ABIN441318
Rogers, Gahring: Upregulation of Nicotinic Acetylcholine Receptor alph4+beta2 through a Ligand-Independent PI3Kbeta Mechanism That Is Enhanced by TNFalpha and the Jak2/p38Mapk Pathways. in PLoS ONE 2015
Show all 4 Pubmed References
Human Monoclonal Annexin A2 Primary Antibody for IF, ELISA - ABIN559875
Menegay, Lee, Tabbara, Cafaro, Urrets-Zavalía, Serra, Bhattacharya: Proteomic analysis of climatic keratopathy droplets. in Investigative ophthalmology & visual science 2008
Show all 3 Pubmed References
Human Monoclonal Annexin A2 Primary Antibody for IF, RNAi - ABIN559874
Deng, Lei, Zhang, Zhang, Zheng, Zhang, Pan, Wang, Tian, Shen, Zhao, Lundberg, Liu, Papasian, Deng: Peripheral blood monocyte-expressed ANXA2 gene is involved in pathogenesis of osteoporosis in humans. in Molecular & cellular proteomics : MCP 2011
Show all 2 Pubmed References
Human Polyclonal Annexin A2 Primary Antibody for IHC (p), WB - ABIN391619
He, Deora, Xiong, Ling, Weksler, Niesvizky, Hajjar: Endothelial cell annexin A2 regulates polyubiquitination and degradation of its binding partner S100A10/p11. in The Journal of biological chemistry 2008
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Cow (Bovine) Polyclonal Annexin A2 Primary Antibody for ELISA, IHC (p) - ABIN257788
Senthilkumaran, Hewson, Ollivett, Bienzle, Lillie, Clark, Caswell: Localization of annexins A1 and A2 in the respiratory tract of healthy calves and those experimentally infected with Mannheimia haemolytica. in Veterinary research 2015
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Cow (Bovine) Polyclonal Annexin A2 Primary Antibody for ELISA, WB - ABIN2477442
Xie, Gao, Li, Zhu, Novakovic, Wang, Ma, Zhou, Gilbert, Shi: Phagocytosis by macrophages and endothelial cells inhibits procoagulant and fibrinolytic activity of acute promyelocytic leukemia cells. in Blood 2012
Human Polyclonal Annexin A2 Primary Antibody for ELISA, WB - ABIN2477443
Moss, Morgan: The annexins. in Genome biology 2004
Human Polyclonal Annexin A2 Primary Antibody for WB - ABIN4253914
Senthilkumaran, Clark, Abdelaziz, Bateman, MacKay, Hewson, Caswell: Increased annexin A1 and A2 levels in bronchoalveolar lavage fluid are associated with resistance to respiratory disease in beef calves. in Veterinary research 2014
Human Monoclonal Annexin A2 Primary Antibody for ELISA, ICC - ABIN251169
Liu, Qu, Lian, Tian, Zhao, Meng, Shou: Unconventional secretion of synuclein-γ promotes tumor cell invasion. in The FEBS journal 2014
ANXA2 and MMP1 (show MMP1 Antibodies) might participate in remodeling during wound healing in the horse.
AnxA2 functions as a critical regulator for amino acid or hormone-induced milk synthesis and mammary gland epithelial cell proliferation via the PI3K-mTOR (show FRAP1 Antibodies)-SREBP-1c (show SREBF1 Antibodies)/Cyclin D1 (show CCND1 Antibodies) signaling pathway.
annexin A2-induced actin bundling is apparently essential for generating active exocytotic sites.
Calves that later developed pneumonia had significantly lower levels of annexin A1 (show ANXA1 Antibodies) and annexin A2, which are potential biomarkers of increased susceptibility to pneumonia in recently weaned and transported feedlot cattle.
Because annexins I and II are abundant and have functions important to the maintenance of placentation, the down-regulation of the annexin genes in the cultured NT (nuclear transfer) trophectoderm may be related to the frequent failures of NT pregnancies.
annexin II binds to CEACAM1 (show CEACAM1 Antibodies) in a breast neoplasm model
show for the first time that annexin A2 (AIIt) can undergo functional reactivation by glutaredoxin (show GRX1 Antibodies), therefore establishing that AIIt is regulated by reversible glutathionylation
AII (show NLRP3 Antibodies) does not bind 1,25-D(3) in a physiologically relevant manner
Data show that the mRNA-binding site of Annexin A2 resides in its domain IV.
The results showed that alkaline phosphatase (ALP) activity was significantly increased in matrix vesicles from calcified bovine vascular smooth muscle cells (BVSMCs) compared with noncalcified BVSMCs, as was annexin II and VI content and (45)Ca uptake.
Annexin A1 has a similar immunogenic expression and correlation with its analog Annexin A2 and their association may be a novel immune target of BD in Han Chinese population
models for annexin A2-mediated vesicle aggregation mechanisms.
Our profiling data provided a rich source for further study of the molecular mechanisms of acquired drug resistance inneuroblastoma ( NB). Further study may determine the role of ANXA2 as a prognostic biomarker and a potential therapeutic target for patients with multidrug-resistant NB.
These results suggested that increased ANXA2 and less expressed beta-catenin (show CTNNB1 Antibodies) were correlated to adenomyosis-associated dysmenorrhea
These data suggested that Annexin A2 induces cisplatin resistance of non-small cell lung cancer (NSCLC)via regulation of JNK/c-Jun/p53 (show TP53 Antibodies) signaling, and provided an evidence that blockade of Annexin A2 could serve as a novel therapeutic approach for overcoming drug resistance in NSCLCs
Results show that Anxa2-Tyr23 phosphorylation is necessary for proliferation, invasion, and metastasis of breast cancer cells in vitro and in vivo. Tyr23-phosphorylated Anxa2 binds to STAT3 (show STAT3 Antibodies) and serves as a key regulator of STAT3 (show STAT3 Antibodies) signaling.
annexin A2 can potentially predict the development of pre-eclampsia. The low annexin A2 levels (<0.89 ng/ml) together with higher blood pressure and proteinuria constitute a higher risk to develop preeclampsia.
Variants in the Annexin A2 (ANXA2) gene directly influence plasma LDL-C levels.
this study showed that Annexin A2 inhibition suppresses proliferation and invasion in ovarian cancer via beta-catenin (show CTNNB1 Antibodies)/EMT (show ITK Antibodies), proposing the potential role of Annexin A2 in the prevention and treatment of ovarian cancer
FNDC3B (show FNDC3B Antibodies) and ANXA2 expression correlate negatively with patient survival in hepatocellular carcinoma
In conclusion, Annexin 2 is the novel host protein identified to interact with classical swine fever virus E2 and promote virus multiplication.
Amino acids R338, N359, G378 of NS5A were revealed to be pivotal for the ANXA2-NS5A interaction.
Taken together, these results indicate that Nsp9 binding partner ANXA2 is beneficial for porcine reproductive and respiratory syndrome virus replication.
Annexin A2 acts in exocytic apical membrane trafficking in small intestinal enterocytes and is proteolytically cleaved in situ by pancreatic proteinases once it has become externalized to the lumenal side of the brush border membrane. [annexin A2]
An octameric model is proposed for the annexin A2/p11(S100A10 (show S100A10 Antibodies)) complex, which exerts annexin A2 function. The proposed structure of the annexin A2/p11 (show S100A10 Antibodies) octamer sheds new light into annexin A2/p11 (show S100A10 Antibodies) interaction.
PTGS2 (show PTGS2 Antibodies) deletion changes the natural distribution of ANXA2 in monocytes/macrophages, increasing TF expression and activity predisposing to venous thrombosis.
Our data indicate that hepatic overexpression of ANX1 (show ANXA1 Antibodies) and ANX2 inhibits APAP-induced expansion of liver injury
This study indicated that AnxA2 played complex roles in traversal of C. neoformans across host brain microvascular endothelial cells.
contributes to pulmonary microvascular integrity by enabling vascular endothelial cadherin (show CDH5 Antibodies)-related phosphatase activity, thereby preventing vascular leak during alveolar hypoxia
our studies show that this G-motif represents a novel and essential determinant for axonal localization of the Anxa2 mRNA mediated by the SMN (show STMN1 Antibodies) complex.
Despite comparable fungal burden, Anxa2(-/-) mice died more rapidly than wild-type mice when infected with Cryptococcus neoformans, and Anxa2(-/-) mice exhibited enhanced inflammatory responses
annexin A2 contributes to lung injury and fibrotic disease by mediating the fibrogenic actions of FXa (show F10 Antibodies).
Our findings reveal a previously undemonstrated function for AnxA2 in inflammatory response in polymicrobial sepsis models
Podxl (show PODXL Antibodies)-overexpression in neural stem/progenitor cells leads to an up-regulation of Annexin A2.
The tick protein sialostatin L2 binds to annexin A2 and inhibits NLRC4 (show NLRC4 Antibodies)-mediated inflammasome activation.
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, annexin II
, Lipocortin II
, annexin A2-like
, calpactin I heavy chain
, calpactin-1 heavy chain
, lipocortin II
, placental anticoagulant protein IV
, protein I
, calpactin I heavy polypeptide
, chromobindin 8
, annexin 2
, 33-kDa calcimedin
, 33-kDa lymphocyte Ca<2+>- binding protein
, 33kDa lymphocyte Ca<2+>- binding protein
, 36-kDa calelectrin