anti-Annexin A2 (ANXA2) Antibodies

ANXA2 encodes a member of the annexin family. Additionally we are shipping Annexin A2 Kits (58) and Annexin A2 Proteins (37) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ANXA2 302 P07355
ANXA2 12306 P07356
ANXA2 56611 Q07936
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Top anti-Annexin A2 Antibodies at antibodies-online.com

Showing 10 out of 242 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: Annexin A2 Antibody [NBP1-31310] - Paraffin-embedded Human pancreas tissue, using antibody at 1:100 dilution. Western Blot: Annexin A2 Antibody [NBP1-31310] - analysis of Annexin A2 Antibody on: A: H1299 B: HeLa S3 C: Hep G2 10% SDS PAGE diluted at 1:1000 100 μL Log in to see 8 to 11 Days
$516.98
Details
Human Goat Un-conjugated ELISA, WB ABIN184687 staining (1µg/ml) of A431 lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated IHC (fro), IHC (p), WB Anti-Annexin A2 antibody, Western blotting Lane 1: Rat Testis Tissue Lysate Lane 2: Rat Lung Tissue Lysate Lane 3: Rat Ovary Tissue Lysate Lane 4: MCF-7 Cell Lysate Lane 5: SMMC Cell Lysate Lane 6: A549 Cell Lysate Lane 7: JURKAT Cell Lysate Anti-Annexin A2 antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue 100 μg Log in to see 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of ANXA2 Antibody (N-term) ABIN391619) in 293 cell line lysates (35 µg/lane). ANXA2 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of anti-ANXA2 Antibody (N-term) (ABIN391619) in mouse lung tissue lysates (35 µg/lane). ANXA2(arrow) was detected using the purified polyclonal antibody (1:60 dilution). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to ANXA2 on HeLa cell.[antibody concentration 10 µg/mL] Western blot analysis of ANXA2 over-expressed 293 cell line, cotransfected with ANXA2 Validated Chimera RNAi used as specificity and loading control. 100 μg Log in to see 8 to 11 Days
$527.50
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to ANXA2 on HeLa cell (antibody concentration 10 µg/mL). ANXA2 monoclonal antibody (M02), clone 1G7 Western Blot analysis of ANXA2 expression in HepG2. 100 μg Log in to see 8 to 11 Days
$527.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ANXA2 Antibody Titration:  1.25ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Lung Lanes:   Lane 1: 20ug mouse GL261 cell lysate Lane 2: 20ug mouse astrocyte cell lysate  Primary Antibody Dilution:   1:250  Secondary Antibody:   Anti-rabbit-HRP  Secondary Antibody Dilution:   1:500  Gene Name:   ANXA2  Submitted by:   Anonymous 100 μL Log in to see 2 to 3 Days
$249.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image Annexin II antibody [N1], N-term detects ANXA2 protein by Western blot analysis. A. 30 µg A549 whole cell lysate/extract B. 30 µg HCT116 whole cell lysate/extract 10 % SDS-PAGE Annexin II antibody [N1], N-term , dilution: 1:1000 IHC-P Image Immunohistochemical analysis of paraffin-embedded Human pancreas tissue, using ANXA2, antibody at 1:100 dilution. 100 μL Log in to see 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image Annexin II antibody detects ANXA2 protein by Western blot analysis. A. 30 µg Rat2 whole cell lysate/extract 10 % SDS-PAGE Annexin II antibody , dilution: 1:1000 WB Image Annexin II antibody detects Annexin II protein by western blot analysis. Non-transfected (-) and human Annexin I or Annexin II-transfected (+) whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Annexin II antibody , diluted at 1:1000. 100 μL Log in to see 3 to 4 Days
$466.18
Details
Cow Rabbit Un-conjugated WB Western blot analysis of Annexin A2 expression in HeLa (A), MCF7 (B), Raw264.7 (C), H9C2 (D), K562 (E), NIH3T3 (F) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details

Top referenced anti-Annexin A2 Antibodies

  1. Human Polyclonal Annexin A2 Primary Antibody for ICC, IF - ABIN441318 : Rogers, Gahring: Upregulation of Nicotinic Acetylcholine Receptor alph4+beta2 through a Ligand-Independent PI3Kbeta Mechanism That Is Enhanced by TNFalpha and the Jak2/p38Mapk Pathways. in PLoS ONE 2015 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal Annexin A2 Primary Antibody for IF, ELISA - ABIN559875 : Menegay, Lee, Tabbara, Cafaro, Urrets-Zavalía, Serra, Bhattacharya: Proteomic analysis of climatic keratopathy droplets. in Investigative ophthalmology & visual science 2008 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal Annexin A2 Primary Antibody for ELISA, ICC - ABIN251169 : Liu, Qu, Lian, Tian, Zhao, Meng, Shou: Unconventional secretion of synuclein-γ promotes tumor cell invasion. in The FEBS journal 2014 (PubMed)
    Show all 2 Pubmed References

  4. Cow (Bovine) Polyclonal Annexin A2 Primary Antibody for ELISA, IHC (p) - ABIN257788 : Senthilkumaran, Hewson, Ollivett, Bienzle, Lillie, Clark, Caswell: Localization of annexins A1 and A2 in the respiratory tract of healthy calves and those experimentally infected with Mannheimia haemolytica. in Veterinary research 2015 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal Annexin A2 Primary Antibody for IHC (p), WB - ABIN391619 : He, Deora, Xiong, Ling, Weksler, Niesvizky, Hajjar: Endothelial cell annexin A2 regulates polyubiquitination and degradation of its binding partner S100A10/p11. in The Journal of biological chemistry 2008 (PubMed)
    Show all 4 Pubmed References

  6. Human Monoclonal Annexin A2 Primary Antibody for IF, RNAi - ABIN559874 : Deng, Lei, Zhang, Zhang, Zheng, Zhang, Pan, Wang, Tian, Shen, Zhao, Lundberg, Liu, Papasian, Deng: Peripheral blood monocyte-expressed ANXA2 gene is involved in pathogenesis of osteoporosis in humans. in Molecular & cellular proteomics : MCP 2011 (PubMed)
    Show all 2 Pubmed References

  7. Human Polyclonal Annexin A2 Primary Antibody for IHC, WB - ABIN6713289 : Huai, Zhang, Liu, Ge, Arendt-Nielsen, Jiang, Yue: Interaction of transient receptor potential vanilloid 4 with annexin A2 and tubulin beta 5. in Neuroscience letters 2013 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal Annexin A2 Primary Antibody for ELISA, WB - ABIN2477443 : Moss, Morgan: The annexins. in Genome biology 2004 (PubMed)

  9. Cow (Bovine) Polyclonal Annexin A2 Primary Antibody for ELISA, WB - ABIN2477442 : Xie, Gao, Li, Zhu, Novakovic, Wang, Ma, Zhou, Gilbert, Shi: Phagocytosis by macrophages and endothelial cells inhibits procoagulant and fibrinolytic activity of acute promyelocytic leukemia cells. in Blood 2012 (PubMed)

  10. Human Polyclonal Annexin A2 Primary Antibody for ELISA, WB - ABIN2753330 : Lamy, Nogues, Combes-Soia, Tsikis, Labas, Mermillod, Druart, Saint-Dizier: Identification by proteomics of oviductal sperm-interacting proteins. in Reproduction (Cambridge, England) 2018 (PubMed)

More Antibodies against Annexin A2 Interaction Partners

Human Annexin A2 (ANXA2) interaction partners

  1. theses data demonstrate that ANXA2 is a specific bleomycin target, and bleomycin binding with ANXA2 impedes TFEB-induced autophagic flux, leading to induction of pulmonary fibrosis.

  2. tenascin-c promoted macrophage migration and VEGF expression through annexin II, the expression of which was modulated by HIF-1alpha.

  3. High ANXA2 expression is associated with Liver Tumorigenesis.

  4. this work uncovers a new peptide motif that binds to and inhibits intracellular annexin A2 as a candidate therapeutic lead for potential translation into clinical applications

  5. Mechanistic studies revealed that FOXD2AS1 upregulated the expression of the miR206 target gene ANXA2 in hepatocellular carcinoma by acting as a miR206 sponge.

  6. study has localised AnxA2/S100A10 complexes to key anatomical locations in the placenta and suggests a role for this complex in amniotic epithelium, trophoblasts and syncytium, in addition to its well-known roles in endothelial cells

  7. Inhibition of ANXA2 will affect the expression of downstream targets and downstream signaling pathways, leading to the suppression of the malignant progression of tumors.

  8. our data suggest that overexpression of peroxiredoxin-2, annexin A2, and heat shock protein beta-1 was correlated with tumor invasion, metastasis, and poor prognosis, and therefore, these proteins may serve as potential diagnostic and therapeutic biomarkers.

  9. aptamer wh6 can block MM cell adhesion to ANXA2 and block the proliferation of MM cells induced by ANXA2

  10. The results demonstrated that ANX2 and stromal tenascin C regulated invasion in addition to stemness and anoikis resistance, which are crucial for metastasis in the progression of pancreatic ductal adenocarcinoma.

  11. Annexin A1 has a similar immunogenic expression and correlation with its analog Annexin A2 and their association may be a novel immune target of BD in Han Chinese population

  12. highly expressed in gastric cancer, related to tumor size, histological differentiation, lymph node metastasis

  13. models for annexin A2-mediated vesicle aggregation mechanisms.

  14. Our profiling data provided a rich source for further study of the molecular mechanisms of acquired drug resistance inneuroblastoma ( NB). Further study may determine the role of ANXA2 as a prognostic biomarker and a potential therapeutic target for patients with multidrug-resistant NB.

  15. These results suggested that increased ANXA2 and less expressed beta-catenin were correlated to adenomyosis-associated dysmenorrhea

  16. These data suggested that Annexin A2 induces cisplatin resistance of non-small cell lung cancer (NSCLC)via regulation of JNK/c-Jun/p53 signaling, and provided an evidence that blockade of Annexin A2 could serve as a novel therapeutic approach for overcoming drug resistance in NSCLCs

  17. Results show that Anxa2-Tyr23 phosphorylation is necessary for proliferation, invasion, and metastasis of breast cancer cells in vitro and in vivo. Tyr23-phosphorylated Anxa2 binds to STAT3 and serves as a key regulator of STAT3 signaling.

  18. annexin A2 can potentially predict the development of pre-eclampsia. The low annexin A2 levels (<0.89 ng/ml) together with higher blood pressure and proteinuria constitute a higher risk to develop preeclampsia.

  19. Variants in the Annexin A2 (ANXA2) gene directly influence plasma LDL-C levels.

  20. this study showed that Annexin A2 inhibition suppresses proliferation and invasion in ovarian cancer via beta-catenin/EMT, proposing the potential role of Annexin A2 in the prevention and treatment of ovarian cancer

Mouse (Murine) Annexin A2 (ANXA2) interaction partners

  1. we demonstrated that Anxa1, Anxa2, and Dyrk1b are upregulated at both the transcriptional and translational levels by the overexpression of GAS1

  2. tenascin-c promoted macrophage migration and VEGF expression through annexin II, the expression of which was modulated by HIF-1alpha.

  3. High ANXA2 expression is associated with Liver Tumorigenesis.

  4. PTGS2 deletion changes the natural distribution of ANXA2 in monocytes/macrophages, increasing TF expression and activity predisposing to venous thrombosis.

  5. Our data indicate that hepatic overexpression of ANX1 and ANX2 inhibits APAP-induced expansion of liver injury

  6. This study indicated that AnxA2 played complex roles in traversal of C. neoformans across host brain microvascular endothelial cells.

  7. contributes to pulmonary microvascular integrity by enabling vascular endothelial cadherin-related phosphatase activity, thereby preventing vascular leak during alveolar hypoxia

  8. our studies show that this G-motif represents a novel and essential determinant for axonal localization of the Anxa2 mRNA mediated by the SMN complex.

  9. Despite comparable fungal burden, Anxa2(-/-) mice died more rapidly than wild-type mice when infected with Cryptococcus neoformans, and Anxa2(-/-) mice exhibited enhanced inflammatory responses

  10. annexin A2 contributes to lung injury and fibrotic disease by mediating the fibrogenic actions of FXa.

  11. Our findings reveal a previously undemonstrated function for AnxA2 in inflammatory response in polymicrobial sepsis models

  12. Podxl-overexpression in neural stem/progenitor cells leads to an up-regulation of Annexin A2.

  13. The tick protein sialostatin L2 binds to annexin A2 and inhibits NLRC4-mediated inflammasome activation.

  14. Data show that annexin A2 (AnxA2) directly exerted negative regulation of inflammatory responses through Toll-like receptor 4 (TLR4)-initiated TRAM protein-TRIF protein pathway occurring on endosomes.

  15. the role of Axna2 is instructive for understanding the development of RA, suppress the effect of Axna2 might provide a new potential measure for treatment of RA.

  16. The role of ARF-6 and Annexin A2 in the invasion of mammalian cells by T. cruzi amastigotes.

  17. Taken together, these findings indicate for the first time that AnxA2 phosphorylation and actin remodeling evoked by oxidative stress depend on the sphingolipid pathway, via MMP2 and p38MAPK.

  18. Data indicate that annexin A2 (AnxA2) regulates the secretion of semaphorin 3D (Sema3D) from pancreatic ductal adenocarcinoma (PDA) cells.

  19. results suggest that legumain expression and activation and cleavage of annexin A2 are regulated by DJ-1 through p53

  20. AnxA2 regulates autophagy, thereby contributing to host immunity against bacteria through the Akt1-mTOR-ULK1/2 signaling pathway

Cow (Bovine) Annexin A2 (ANXA2) interaction partners

  1. ClfA binds with AnnexinA2 and this interaction could mediate S. aureus invasion into bovine mammary epithelial cells.

  2. AnxA2 functions as a critical regulator for amino acid or hormone-induced milk synthesis and mammary gland epithelial cell proliferation via the PI3K-mTOR-SREBP-1c/Cyclin D1 signaling pathway.

  3. annexin A2-induced actin bundling is apparently essential for generating active exocytotic sites.

  4. Annexins A1 and A2 are proteins produced by airway epithelial cells that may prevent inflammation in the healthy lung and be relevant to development of pneumonia in stressed cattle.

  5. Calves that later developed pneumonia had significantly lower levels of annexin A1 and annexin A2, which are potential biomarkers of increased susceptibility to pneumonia in recently weaned and transported feedlot cattle.

  6. Because annexins I and II are abundant and have functions important to the maintenance of placentation, the down-regulation of the annexin genes in the cultured NT (nuclear transfer) trophectoderm may be related to the frequent failures of NT pregnancies.

  7. annexin II binds to CEACAM1 in a breast neoplasm model

  8. show for the first time that annexin A2 (AIIt) can undergo functional reactivation by glutaredoxin, therefore establishing that AIIt is regulated by reversible glutathionylation

  9. AII does not bind 1,25-D(3) in a physiologically relevant manner

  10. Data show that the mRNA-binding site of Annexin A2 resides in its domain IV.

  11. The results showed that alkaline phosphatase (ALP) activity was significantly increased in matrix vesicles from calcified bovine vascular smooth muscle cells (BVSMCs) compared with noncalcified BVSMCs, as was annexin II and VI content and (45)Ca uptake.

Pig (Porcine) Annexin A2 (ANXA2) interaction partners

  1. ANXA2 can interact with vimentin and enhance porcine reproductive and respiratory syndrome virus (PRRSV) growth. This contributes to the regulation of PRRSV replication in infected cells and may have implications for the future antiviral strategies.

  2. In conclusion, Annexin 2 is the novel host protein identified to interact with classical swine fever virus E2 and promote virus multiplication.

  3. Amino acids R338, N359, G378 of NS5A were revealed to be pivotal for the ANXA2-NS5A interaction.

  4. Taken together, these results indicate that Nsp9 binding partner ANXA2 is beneficial for porcine reproductive and respiratory syndrome virus replication.

  5. Annexin A2 acts in exocytic apical membrane trafficking in small intestinal enterocytes and is proteolytically cleaved in situ by pancreatic proteinases once it has become externalized to the lumenal side of the brush border membrane. [annexin A2]

  6. An octameric model is proposed for the annexin A2/p11(S100A10) complex, which exerts annexin A2 function. The proposed structure of the annexin A2/p11 octamer sheds new light into annexin A2/p11 interaction.

Horse (Equine) Annexin A2 (ANXA2) interaction partners

  1. ANXA2 and MMP1 might participate in remodeling during wound healing in the horse.

Annexin A2 (ANXA2) Antigen Profile

Protein Summary

This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Annexin A2 (ANXA2) Antibodies

  • annexin A2 (ANXA2) antibody
  • annexin A2 (Anxa2) antibody
  • annexin A2 (anxa2) antibody
  • annexin A2 S homeolog (anxa2.S) antibody
  • anx2 antibody
  • anx2l4 antibody
  • anxa2 antibody
  • anxa2-a antibody
  • anxa2-b antibody
  • AW215814 antibody
  • cal1h antibody
  • lip2 antibody
  • lpc2 antibody
  • lpc2d antibody
  • MGC76145 antibody
  • p36 antibody
  • pap-i antibody
  • PAP-IV antibody

Protein level used designations for anti-Annexin A2 (ANXA2) Antibodies

annexin II , annexin-2 , calpactin I heavy chain , calpactin I heavy polypeptide , calpactin-1 heavy chain , chromobindin 8 , chromobindin-8 , lipocortin II , placental anticoagulant protein IV , protein I , 33-kDa calcimedin , 33-kDa lymphocyte Ca<2+>- binding protein , 33kDa lymphocyte Ca<2+>- binding protein , 36-kDa calelectrin , PAP-IV , p36 , annexin A2 , Lipocortin II , annexin 2 , annexin A2-like , Annexin II type I , Annexin-2-A , Calpactin I heavy chain , Calpactin-1 heavy chain , annexin A2-A , annexin II type I , annexin-2-A

GENE ID SPECIES
302 Homo sapiens
12306 Mus musculus
56611 Rattus norvegicus
282689 Bos taurus
394517 Xenopus (Silurana) tropicalis
396297 Gallus gallus
403435 Canis lupus familiaris
406192 Sus scrofa
706240 Macaca mulatta
747018 Pan troglodytes
100048993 Ovis aries
100054320 Equus caballus
100173821 Pongo abelii
100397902 Callithrix jacchus
100716883 Cavia porcellus
100357671 Oryctolagus cuniculus
397754 Xenopus laevis
101691698 Mustela putorius furo
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