anti-Anoctamin 5 (ANO5) Antibodies

ANO5 encodes a member of the anoctamin family of transmembrane proteins. Additionally we are shipping Anoctamin 5 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ANO5 203859 Q75V66
ANO5 233246 Q75UR0
ANO5    
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Anoctamin 5 Antibodies at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of ANO5 Antibody (C-term) (ABIN652521) in mouse spleen tissue lysates (35 µg/lane). ANO5 (arrow) was detected using the purified polyclonal antibody. ANO5 Antibody (C-term) (ABIN652521) immunohistochemistry analysis in formalin fixed and paraffin embedded human lymph tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of AP21362PU-N ANO5 Antibody (C-term) in Mouse spleen tissue lysates (35 µg/lane). ANO5 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: ANO5 Antibody [NBP2-32401] - liver cancer Immunohistochemistry: ANO5 Antibody [NBP2-32401] - liver 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, IHC, IHC (p), WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details
Human Rabbit FITC ELISA, IHC, IHC (p), WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details
Human Rabbit APC ELISA, IHC, IHC (p), WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details
Human Rabbit PE ELISA, IHC, IHC (p), WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details
Human Rabbit Biotin ELISA, IHC, IHC (p), WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details
Human Rabbit Un-conjugated IHC, WB   100 μL Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB   200 μL Log in to see 7 to 9 Days
$793.83
Details

Top referenced anti-Anoctamin 5 Antibodies

  1. Human Polyclonal ANO5 Primary Antibody for IHC (p), WB - ABIN652521 : Tsutsumi, Kamata, Vokes, Maruoka, Nakakuki, Enomoto, Omura, Amagasa, Nagayama, Saito-Ohara, Inazawa, Moritani, Yamaoka, Inoue, Itakura: The novel gene encoding a putative transmembrane protein is mutated in gnathodiaphyseal dysplasia (GDD). in American journal of human genetics 2004 (PubMed)
    Show all 2 Pubmed References

More Antibodies against Anoctamin 5 Interaction Partners

Human Anoctamin 5 (ANO5) interaction partners

  1. First direct demonstration of Ca(2 (show CA2 Antibodies)+)-dependent Phospholipid scrambling activity for TMEM16E; this suggests a gain-of-function phenotype related to a Gnathodiaphyseal dysplasia mutation.

  2. After Ano5 gene knock-down with shRNA in MC3T3-E1 osteoblast precursors the authors saw elevated expression of osteoblast-related genes such as Col1a1 (show COL1A1 Antibodies), osteocalcin (show BGLAP Antibodies), osterix (show SP7 Antibodies) and Runx2 (show RUNX2 Antibodies) as well as increased mineral nodule formation in differentiating cells. The data suggest that ANO5 plays a role in osteoblast differentiation.

  3. The Limb-girdle muscular dystrophy 2L family was characterized by mild chronic myopathy and bilateral gastrocnemius hypertrophy with obviously increased creatine kinase levels. Pathological changes included atrophy of fibers with interstitial connective tissues hyperplasia. The pathogenic allele was a c.220C> T mutation in the ANO5 gene.

  4. A heterozygous mutation in the ANO5 gene c.1067G > A (p.Cys356Tyr) was identified in both affected individuals in a Russian family with giant cementoma and bone fractures consistent with a diagnosis of gnathodiaphyseal dysplasia.

  5. Results show that ANO5 is downregulated in thyroid cancer and, negatively associated with lymph node metastasis. Its inhibition promotes the migration and invasion of thyroid cancer cells suggesting it as a tumor marker.

  6. Study characterized 12 newly identified and 2 previously identified patients with ANO5 mutations from 11 families. Material was genetically homogeneous with most patients homozygous for the Finnish founder variant c.2272C>T (p.Arg758Cys). In one family, study found a novel p.Met470Arg variant compound heterozygous with p.Arg758Cys.

  7. Asymptomatic, sometimes mild hyperCKemia or exercise intolerance is a presentation of ANO5-related myopathy.

  8. Here we show that Ano5-deficient mice have reduced capacity to repair the sarcolemma following laser-induced damage, exhibit delayed regeneration after cardiotoxin injury and suffer from defective myoblast fusion necessary for the proper repair and regeneration of multinucleated myotubes. these data suggest that ANO5 plays an important role in sarcolemmal membrane dynamics.

  9. Study screened the ANO5 gene in 786 myopathic patients and 52 controls by combining NGS and Sanger sequencing. In the cohort of patients, thirty-three are homozygous or compound heterozygous for causative mutations in ANO5

  10. supervised aerobic exercise training is safe and effective in improving oxidative capacity and muscle function in patients with anoctamin 5 deficiency

Mouse (Murine) Anoctamin 5 (ANO5) interaction partners

  1. Here we show that Ano5-deficient mice have reduced capacity to repair the sarcolemma following laser-induced damage, exhibit delayed regeneration after cardiotoxin injury and suffer from defective myoblast fusion necessary for the proper repair and regeneration of multinucleated myotubes. these data suggest that ANO5 plays an important role in sarcolemmal membrane dynamics.

  2. TMEM16E(-/-) sperm showed no apparent defect in morphology, beating, mitochondrial function, capacitation, or binding to zona pellucida. However, they showed reduced motility and inefficient fertilization of cumulus-free but zona-intact eggs in vitro.

  3. Ano5 mRNA and protein are widely expressed in the esophagus, stomach, duodenum, colon and rectum but Ano5 immunoreactivity are only detected in the mucosal layer, except for the muscular layer of the upper esophagus, which consists of skeletal muscle.

  4. characterized the complete cDNA sequence and genomic organization of the mouse GDD1 gene

  5. These observations suggest diverse cellular role(s) of GDD1 in the development of musculoskeletal system.

Anoctamin 5 (ANO5) Antigen Profile

Protein Summary

This gene encodes a member of the anoctamin family of transmembrane proteins. The encoded protein is likely a calcium activated chloride channel. Mutations in this gene have been associated with gnathodiaphyseal dysplasia. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with anti-Anoctamin 5 (ANO5) Antibodies

  • anoctamin 5 L homeolog (ano5.L) antibody
  • anoctamin 5 (ANO5) antibody
  • anoctamin 5a (ano5a) antibody
  • anoctamin 5 (ano5) antibody
  • anoctamin 5 (Ano5) antibody
  • 9330162L24 antibody
  • ano5 antibody
  • Gdd1 antibody
  • LGMD2L antibody
  • MGC82557 antibody
  • si:dkey-261m9.4 antibody
  • Tmem16e antibody

Protein level used designations for anti-Anoctamin 5 (ANO5) Antibodies

anoctamin 5 , transmembrane protein 16E , anoctamin-5 , anoctamin-5-like , tmem16ea , gnathodiaphyseal dysplasia 1 protein , integral membrane protein GDD1 , limb girdle muscular dystrophy 2L (autosomal recessive) , gnathodiaphyseal dysplasia 1 protein homolog

GENE ID SPECIES
446645 Xenopus laevis
485416 Canis lupus familiaris
100072055 Equus caballus
100140158 Bos taurus
100340377 Oryctolagus cuniculus
100389212 Callithrix jacchus
100459066 Pongo abelii
100484835 Ailuropoda melanoleuca
100534737 Danio rerio
100549161 Meleagris gallopavo
100567373 Anolis carolinensis
100587082 Nomascus leucogenys
100617099 Monodelphis domestica
203859 Homo sapiens
233246 Mus musculus
Selected quality suppliers for anti-Anoctamin 5 (ANO5) Antibodies
Did you look for something else?