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AGR3 encodes a member of the immunoglobulin superfamily. Additionally we are shipping Anterior Gradient 3 Homolog (Xenopus Laevis) Antibodies (82) and Anterior Gradient 3 Homolog (Xenopus Laevis) Proteins (10) and many more products for this protein.
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Human AGR3 ELISA Kit for Sandwich ELISA - ABIN828029
Garczyk, von Stillfried, Antonopoulos, Hartmann, Schrauder, Fasching, Anzeneder, Tannapfel, Ergönenc, Knüchel, Rose, Dahl: AGR3 in breast cancer: prognostic impact and suitable serum-based biomarker for early cancer detection. in PLoS ONE 2015
Data show the potential usability of anterior gradient homolog 3 (AGR3) and anterior gradient homolog 2 (AGR2 (show AGR2 ELISA Kits)) as biomarkers for blood-based early detection of breast cancer.
AGR3 is a specialized member of the PDI (show PADI1 ELISA Kits) family that plays an unexpected role in the regulation of CBF (show CEBPZ ELISA Kits) and mucociliary clearance in the airway.
Relying on available data and in silico analyses, study shows that AGR2 (show AGR2 ELISA Kits) and AGR3 proteins are co-expressed or uncoupled in context-dependent manners in diverse carcinomas and healthy tissues.
AGR3 was is predominantly expressed in liver cholangiocytes but not present in liver hepatocytes, making this protain a good marker for differential diagnosis of intrahepatic cholangiocarcinoma
AGR3 expression in ovarian cancer is independent of oestrogen-receptor expression.
AGR3 could serve as a prognostic marker for survival in patients with low grade and high grade serous ovarian carcinomas.
hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan [hAG-3 protein]
specific induction of Hag2 (show AGR2 ELISA Kits) and Hag3 during hormone-induced breast carcinomas further support developmental specificity for the PDI/ERp (show PDIA3 ELISA Kits) family members
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described.
, anterior gradient 3 homolog
, anterior gradient homolog 3
, anterior gradient protein 3 homolog
, breast cancer membrane protein 11
, protein disulfide isomerase family A, member 18
, anterior gradient protein 3