anti-Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3A (APOBEC3A) Antibodies

APOBEC3A is a member of the cytidine deaminase gene family. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
APOBEC3A 200315 P31941
APOBEC3A    
APOBEC3A    
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Top anti-APOBEC3A Antibodies at antibodies-online.com

Showing 10 out of 76 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, FACS, IF, IHC, WB   100 μg Log in to see 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated WB Western blot analysis of APOBEC3A expression in HEK293T (A), SP2/0 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: APOBEC3A Antibody [NBP1-88999] - Staining of human cell line U-2 OS shows positivity in cytoplasm. Immunohistochemistry-Paraffin: APOBEC3A Antibody [NBP1-88999] - Staining of human bone marrow shows strong nuclear positivity in hematopoietic cells. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from Jurkat cells, using APOBEC3A Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Goat Un-conjugated ELISA, IHC, IHC (p) Anti-APOBEC3A antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1100036 concentration 27454 ug/ml. Anti-APOBEC3A antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 16 Days
$181.73
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB ABIN6272242 staining Hela by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody. Western blot analysis of APOBEC3A using Jurkat whole cell lysates 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Goat Un-conjugated EIA, IHC (p) Paraffin Embedded Human Tonsil stained with APOBEC3A Antibody at 3.8 µg/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 0.1 mg Log in to see 6 to 8 Days
$445.50
Details
Human Rabbit Un-conjugated WB APOBEC3A Antibody (N-term) (ABIN1881066) western blot analysis in ZR-75-1 cell line lysates (35 µg/lane). This demonstrates the APOBEC3A antibody detected the APOBEC3A protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details

Top referenced anti-APOBEC3A Antibodies

  1. Human Polyclonal APOBEC3A Primary Antibody for WB - ABIN1881066 : Thielen, McNevin, McElrath, Hunt, Klein, Lingappa: Innate immune signaling induces high levels of TC-specific deaminase activity in primary monocyte-derived cells through expression of APOBEC3A isoforms. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal APOBEC3A Primary Antibody for IHC (p), ELISA - ABIN543437 : Madsen, Anant, Rasmussen, Gromov, Vorum, Dumanski, Tommerup, Collins, Wright, Dunham, MacGinnitie, Davidson, Celis: Psoriasis upregulated phorbolin-1 shares structural but not functional similarity to the mRNA-editing protein apobec-1. in The Journal of investigative dermatology 1999 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal APOBEC3A Primary Antibody for ELISA - ABIN548224 : Goila-Gaur, Khan, Miyagi, Kao, Strebel: Targeting APOBEC3A to the viral nucleoprotein complex confers antiviral activity. in Retrovirology 2007 (PubMed)

More Antibodies against APOBEC3A Interaction Partners

Human Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3A (APOBEC3A) interaction partners

  1. Data show the crystal structure of a complex of a cytidine deaminase (APOBEC3A) with single-stranded DNA (ssDNA) bound in the active site at 2.2 A.

  2. The results suggest that APOBEC3A expression is downregulated during progression towards invasiveness in human papillomaviruse (HPV)-negative penile squamous cell carcinoma (SCC), but maintained in HPV-positive penile SCC.

  3. Enhanced apolipoprotein APOBEC3A repressed human papillomavirus HPV11 E6 expression through gene hypermutation, and recombinant human interferon-omega rhIFN-omega might be an effective agent against HPV11 infection by up-regulation of APOBEC3A.

  4. APOBEC3A is the most likely gene to be active in HPV+ HNSCC. APOBEC activity correlates with upregulation of immune signaling pathways, supporting the hypothesis that APOBEC activity could be activated as part of the innate immune response

  5. direct evidence that both A3A and HPV16 E7 interact with CUL2, suggesting that the E7-CUL2 complex formed during HPV infection may regulate A3A protein levels in the cell.

  6. review of current understanding of APOBEC3A and APOBEC3B biology in human papillomavirus Infection restriction, evolution, and associated cancer mutagenesis

  7. p53 activation alters APOBECA3 gene regulation.Activated p53 binds transcriptional regulatory regions of APOBECA3 gene.

  8. These results highlight the fundamental impact of APOBEC3A overexpression on human transcriptome by widespread RNA editing.

  9. High-level APOBEC3A expression is associated with better overall survival, especially among patients carrying APOBEC3B-deletion alleles in Taiwanese oral squamous cell carcinoma patients.

  10. Our study demonstrates that 20% of C-->T and C-->G mutations in the TpCpW context-where W denotes A or T, segregating as polymorphisms in human population-or 1.4% of all heritable mutations are attributable to APOBEC3A/B activity.

  11. findings reveal the role of A3A as a potent anti-Human cytomegalovirus (HCMV) innate barrier, activated by HCMV infection in the authentic tissues of the maternal-fetal interface. These findings pave the way to new insights into the potential impact of APOBEC proteins on HCMV pathogenesis.

  12. APOBEC3A/B and HLA-DQA1 are powerful biomarkers for systemic sclerosis risk evaluation and contribute to the susceptibility to systemic sclerosis.

  13. High APOBEC3A expression is associated with acute myelogenous leukemia.

  14. Steady-state kinetic analysis reveals that APOBEC3A (A3A) discriminates against all ox-mCs by 3700-fold, arguing that ox-mC deamination does not contribute substantially to demethylation. A3A is, by contrast, highly proficient at C/mC deamination.

  15. a solution-state model of APOBEC3A interaction with its single-stranded DNA substrate obtained with the 'method of small changes', is reported.

  16. exposures to relevant environmental factors might induce APOBEC3A or APOBEC3B expression above genotoxic levels and initiate tumorigenesis in a tissue-specific manner in the right cellular environment where ssDNA is available

  17. APOBEC-induced mutagenesis is associated with chemotherapy-resistant urothelial carcinoma.

  18. Hyperthermia may induce regression of genital warts via APOBEC3A expression in patients diagnosed with genital warts.

  19. APOBEC3A proteins were up regulated in genital warts cell cultures taken from patients diagnosed with human papillomavirus infections.

  20. We have demonstrated that the APOBEC3A gene of primates displays sequence variation consistent with a role in host defense against a changing pathogen or set of pathogens. Our data suggest that though APOBEC3A potently restricts LINE-1 retroelements, the rapid evolution in APOBEC3A was likely not driven by LINE-1.

APOBEC3A Antigen Profile

Protein Summary

This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with APOBEC3A

  • apolipoprotein B mRNA editing enzyme catalytic subunit 3A (APOBEC3A) antibody
  • apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A (APOBEC3Z1) antibody
  • apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3Z1 (APOBEC3Z1) antibody
  • similar to ARP10 protein (APOBEC3A) antibody
  • apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A (APOBEC3A) antibody
  • A3A antibody
  • APOBEC3A antibody
  • APOBEC3Z1 antibody
  • ARP3 antibody
  • bK150C2.1 antibody
  • PHRBN antibody

Protein level used designations for APOBEC3A

DNA dC->dU-editing enzyme APOBEC-3A , phorbolin 1 , phorbolin-1 , probable DNA dC->dU-editing enzyme APOBEC-3A , apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A , similar to ARP10 protein

GENE ID SPECIES
200315 Homo sapiens
507162 Bos taurus
610245 Canis lupus familiaris
702708 Macaca mulatta
744498 Pan troglodytes
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