anti-Arylacetamide Deacetylase (Esterase) (AADAC) Antibodies

Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens [provided by RefSeq, Jul 2008]..

list all antibodies Gene Name GeneID UniProt
Anti-Human AADAC AADAC 13 P22760
Anti-Rat AADAC AADAC 57300 Q9QZH8
Anti-Mouse AADAC AADAC 67758 Q99PG0
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Top anti-Arylacetamide Deacetylase (Esterase) Antibodies at antibodies-online.com

Showing 10 out of 58 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB Host:  Rabbit  Target Name:  AADAC  Sample Type:  Human Fetal Liver  Antibody Dilution:  1.0ug/ml WB Suggested Anti-AADAC Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Transfected 293T 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-AADAC Antibody Titration:  2.5ug/ml  Positive Control:  Human Liver 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged AADAC is approximately 3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of AADAC Antibody (C-term) (ABIN390780) in 293 cell line lysates (35 µg/lane). AADAC (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma with AADAC Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Horse Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Horse Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged AADAC is approximately 3ng/ml as a capture antibody. Western Blot detection against Immunogen (36.74 KDa) . 100 μg Log in to see 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated WB Western Blot: AADAC Antibody [NBP1-62428] - Transfected 293T cell lysate, concentration 0.2-1 ug/ml. Western Blot: AADAC Antibody [NBP1-62428] - Human Fetal Liver, Antibody Dilution: 1.0 ug/ml. 100 μL Log in to see 8 to 11 Days
$485.88
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human colon carcinoma labeled with Rabbit Anti AADAC Polyclonal Antibody, Unconjugated (ABIN1387867) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$306.90
Details

Top referenced anti-Arylacetamide Deacetylase (Esterase) Antibodies

  1. Human Monoclonal AADAC Primary Antibody for ELISA, WB - ABIN513029 : Watanabe, Fukami, Nakajima, Takamiya, Aoki, Yokoi: Human arylacetamide deacetylase is a principal enzyme in flutamide hydrolysis. in Drug metabolism and disposition: the biological fate of chemicals 2009 (PubMed)
    Show all 5 Pubmed References

More Antibodies against Arylacetamide Deacetylase (Esterase) Interaction Partners

Human Arylacetamide Deacetylase (Esterase) (AADAC) interaction partners

  1. Data suggest that metabolism (and possibly pharmacokinetics) of hypnotic nitrazepam involves liver enzymes AOX1 (aldehyde oxidase 1 (show AOX1 Antibodies)), NAT2 (N-acetyltransferase 2 (show NAT2 Antibodies)), AADAC (arylacetamide deacetylase), and CYP3A4 (cytochrome P450 3A4 (show CYP3A4 Antibodies)).

  2. Data suggest that AADAC in hepatocyte microsomes hydrolyzes ketoconazole, a synthetic imidazole antifungal agent, to N-deacetyl ketoconazole and thus triggers hepatocellular toxicity.

  3. AADAC deletion is a candidate susceptibility factor for Gilles de la Tourette Syndrome

  4. Translational N-glycosylation of AADAC plays a crucial role in regulating AADAC enzyme activity.

  5. Lipolysis of cellular TG and VLDL production were impaired in HCV infected cells during the early peak of viral infection. This was partially explained by an apparent deficiency of a putative TG lipase (show LIPG Antibodies), arylacetamide deacetylase (AADAC).

  6. An AADAC*3 allele yields decreased enzyme activity in liver microsomes.

  7. human AADAC was the enzyme responsible for the deacetylation of rifamycins and would affect the induction rate of drug-metabolizing enzymes by rifamycins and their induced hepatotoxicity.

  8. two intrinsic endoplasmic reticulum (ER) proteins, 11beta-hydroxysteroid dehydrogenase, isozyme 1 (11beta-HSD (show CHST3 Antibodies)) and the 50-kDa esterase (show ESD Antibodies) (E3), sharing some amino acid sequence motifs in their N-terminal transmembrane (TM) domains.

Mouse (Murine) Arylacetamide Deacetylase (Esterase) (AADAC) interaction partners

  1. Expression of AADA cDNA in McArdle-RH7777 cells significantly reduced intracellular triacylglycerol levels and apolipoprotein B (show APOB Antibodies) secretion and increased fatty acid oxidation.

Arylacetamide Deacetylase (Esterase) (AADAC) Antigen Profile

Protein Summary

Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens

Gene names and symbols associated with AADAC

  • arylacetamide deacetylase (LOC100056411) antibody
  • arylacetamide deacetylase (aadac) antibody
  • arylacetamide deacetylase (AADAC) antibody
  • arylacetamide deacetylase S homeolog (aadac.S) antibody
  • arylacetamide deacetylase (LOC100451808) antibody
  • Arylacetamide deacetylase (ACD3) antibody
  • arylacetamide deacetylase (PTRG_10278) antibody
  • Arylacetamide deacetylase (aaad) antibody
  • arylacetamide deacetylase (Aadac) antibody
  • arylacetamide deacetylase (esterase) (AADAC) antibody
  • 5033417E09Rik antibody
  • Aada antibody
  • AADAC antibody
  • AI265437 antibody
  • CES5A1 antibody
  • DAC antibody
  • MGC89272 antibody

Protein level used designations for AADAC

arylacetamide deacetylase (esterase) , arylacetamide deacetylase-like , Arylacetamide deacetylase , arylacetamide deacetylase , arylacetamide deacetylase-like 2

GENE ID SPECIES
100056411 Equus caballus
448381 Xenopus (Silurana) tropicalis
460785 Pan troglodytes
100126645 Xenopus laevis
100393374 Callithrix jacchus
100451808 Pongo abelii
4836710 Scheffersomyces stipitis CBS 6054
6348579 Pyrenophora tritici-repentis Pt-1C-BFP
100195711 Salmo salar
425034 Gallus gallus
13 Homo sapiens
477115 Canis lupus familiaris
57300 Rattus norvegicus
519557 Bos taurus
67758 Mus musculus
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