anti-Atlastin GTPase 1 (ATL1) Antibodies

The protein encoded by ATL1 is a GTPase and a Golgi body transmembrane protein. Additionally we are shipping ATL1 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ATL1 51062 Q8WXF7
ATL1 73991 Q8BH66
ATL1 362750 Q6PST4
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Top anti-ATL1 Antibodies at antibodies-online.com

Showing 10 out of 60 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB ATL1 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35µg/lane).This demonstrates the ATL1 antibody detected the ATL1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB ATL1 Antibody (C-term)  western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the ATL1 antibody detected the ATL1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA, WB SPG3A monoclonal antibody (M03), clone 1B9 Western Blot analysis of SPG3A expression in IMR-32 . Detection limit for recombinant GST tagged SPG3A is approximately 1ng/ml as a capture antibody. 100 μg Log in to see 11 to 12 Days
$440.00
Details
Human Mouse Un-conjugated ELISA, WB 100 μg Log in to see 7 to 9 Days
$537.17
Details
Human Rabbit Un-conjugated IF, IHC, WB 100 μL Log in to see 16 Days
$334.02
Details
Human Mouse Un-conjugated WB SPG3A monoclonal antibody (M10), clone 1B11. Western Blot analysis of SPG3A expression in IMR-32. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated WB SPG3A monoclonal antibody (M03), clone 1B9 Western Blot analysis of SPG3A expression in IMR-32. Detection limit for recombinant GST tagged SPG3A is approximately 1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated ELISA, FACS, IHC, WB ELISA: SPG3A Antibody (1F6B12)  - Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Western Blot: SPG3A Antibody (1F6B12)  - Analysis using ATL1 mAb against HEK293 (1) and ATL1 (AA: 1-100)-hIgGFc transfected HEK293 (2) cell lysate. 0.1 mL Log in to see 7 to 9 Days
$514.63
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 11 to 12 Days
$305.71
Details

ATL1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against ATL1 Interaction Partners

Zebrafish Atlastin GTPase 1 (ATL1) interaction partners

  1. This study suggests that atlastin may regulate BMP receptor (show BMPR1A Antibodies) trafficking. and genetic or pharmacological inhibition of BMP signaling was sufficient to rescue the loss of mobility and spinal motor axon defects of atl1 morphants.

Human Atlastin GTPase 1 (ATL1) interaction partners

  1. Variants in the ATL1 gene are a less frequent cause of hereditary spastic paraplegia among Czech patients than has been previously reported among other populations.

  2. This study demonstrated that ATL1 gene mutation associated with hereditary spastic paraplegias in group of Polish patients

  3. The results suggest that tethering and lipid mixing are catalyzed concurrently by atlastin GTPase (show RACGAP1 Antibodies) hydrolysis but that the energy requirement for lipid mixing exceeds that for tethering, and the full energy released through crossover formation is necessary for fusion.

  4. that Atlastin 1 mutations may cause autosomal recessively inherited paraplegia with an underlying loss-of-function mechanism. Hence, patients with recessive forms of HSP should also be tested for the Atlastin 1 gene.

  5. This study showed that the mutations of were detected in SPG11 (show SPG11 Antibodies), ATL1, NIPA1 (show NIPA1 Antibodies), and ABCD1 (show ABCD1 Antibodies) in patient with hereditary spastic paraplegia.

  6. We identified two novel mutations and two previously reported mutations in SPAST (show SPAST Antibodies) and ATL1, respectively. The family with the ATL1 c.1204T>G mutation exhibited male-lethality, female infancy-onset, and pseudo- X-linked dominant transmission

  7. Novel splicing pathogenic variants were identified in ATL1 genes of Korean patients with hereditary spastic paraplegia.

  8. a deficit in the membrane fusion activity of atlastin1 may be a key contributor, but is not required, for hereditary spastic paraplegia causation.

  9. These results suggest that the three ATLs have different capacities to mediate endoplasmic reticulum fusion, with ATL1 being the strongest and ATL3 (show ATL3 Antibodies) being the weakest.

  10. purified and reconstituted human ATL1 exhibited no in vitro fusion activity. When the cytosolic segment of human ATL1 was connected to the transmembrane (TM) region and C-terminal tail (CT) of Drosophila ATL

Mouse (Murine) Atlastin GTPase 1 (ATL1) interaction partners

  1. Endoplasmic reticulum morphology is markedly disrupted in ATL1, ATL2 (show ATL2 Antibodies), and ATL3 (show ATL3 Antibodies) knockout cells.

  2. VCP (valosin-containing protein (show vcp Antibodies)), together with its cofactor P47 (show MFGE8 Antibodies) and the endoplasmic reticulum (ER) morphology regulator ATL1 (Atlastin-1), regulates tubular ER formation

  3. This publication discusses functional and mutational aspects of atlastin GTPase 1 in humans.

ATL1 Antigen Profile

Protein Summary

The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with ATL1

  • atlastin GTPase 1 (ATL1) antibody
  • atlastin GTPase 1 (atl1) antibody
  • atlastin GTPase 1 (Atl1) antibody
  • 4930435M24Rik antibody
  • AD-FSP antibody
  • Adfsp antibody
  • ATL1 antibody
  • atlastin antibody
  • Atlastin-1 antibody
  • atlastin1 antibody
  • fj46c01 antibody
  • Fsp1 antibody
  • GBP3 antibody
  • HSN1D antibody
  • MGC146251 antibody
  • Spg3 antibody
  • Spg3a antibody
  • wu:fj46c01 antibody

Protein level used designations for ATL1

atlastin GTPase 1 , spastic paraplegia 3A (autosomal dominant) , atlastin-1 , atlastin-1-like , GBP-3 , GTP-binding protein 3 , brain-specific GTP-binding protein , guanine nucleotide-binding protein 3 , guanylate-binding protein 3 , hGBP3 , spastic paraplegia 3 protein A , spastic paraplegia 3A homolog

GENE ID SPECIES
467452 Pan troglodytes
480318 Canis lupus familiaris
571909 Danio rerio
779669 Xenopus (Silurana) tropicalis
100158193 Sus scrofa
100413587 Callithrix jacchus
100347174 Oryctolagus cuniculus
100603089 Nomascus leucogenys
51062 Homo sapiens
73991 Mus musculus
362750 Rattus norvegicus
535424 Bos taurus
100173943 Pongo abelii
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