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Acts as a ventralizing factor during embryogenesis. Additionally we are shipping Axin Interactor, Dorsalization Associated Proteins (10) and Axin Interactor, Dorsalization Associated Kits (4) and many more products for this protein.
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A dorsalization pathway that is exerted by Axin/JNK signaling and its inhibitor Aida during vertebrate embryogenesis, is defined.
Aida blocks Axin-mediated JNK activation by disrupting Axin homodimerization. In zebrafish embryos, the dorsalization induced by axin could be repressed by aida. This activity of aida is conferred by its ability to block Axin-mediated JNK activity.
Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling (By similarity).
chromosome 1 open reading frame 80
, axin interactor, dorsalization-associated protein
, UPF0491 protein C1orf80 homolog
, axin interaction partner and dorsalization antagonist