anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) Antibodies

The protein encoded by BIRC7 is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. Additionally we are shipping Baculoviral IAP Repeat-Containing 7 Kits (19) and Baculoviral IAP Repeat-Containing 7 Proteins (17) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BIRC7 79444 Q96CA5
BIRC7 296468  
BIRC7 329581 A2AWP0
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Top anti-Baculoviral IAP Repeat-Containing 7 Antibodies at antibodies-online.com

Showing 10 out of 179 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ICC, IF, WB Western blot detection of Livin in A) Livin transfected cell lysate and B) U266 cell lysate. A protein band of apprximate molecular weight of 31 kDa is detected using NB at 2 ug/ml dilution Western Blot: Livin Antibody (88C570) [ABIN2525068] - detection of Livin in A) Livin transfected cell lysate and B) Molt4 cell lysate. A protein band of apprximate molecular weight of 31 kDa is detected using this antibody. 0.1 mg Log in to see 7 to 9 Days
$444.19
Details
Human Goat Un-conjugated ELISA, WB ABIN184599 staining (0.3µg/ml) of MOLT4 lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 6 to 7 Days
$429.62
Details
Human Rabbit Un-conjugated ELISA, WB Observed bind size: 33KD Anti-  Livin antibody, Western blottingAll lanes: Anti Livin  at 0.5ug/ml  Lane 1: HELA Whole Cell Lysate at 40ug  Lane 2: A431 Whole Cell Lysate at 40ug Predicted bind size: 33KD Observed bind size: 33KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-BIRC7 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), IP, IHC, WB Western blot analysis of full-length, recombinant human Livin using ABIN252145 at 1:2000. Immunohistochemical analysis of Livin in formalin-fixed, paraffin embedded human tonsil (secondary nodule) using ABIN252145 at 1:2000. Hematoxylin-eosin counterstain. 0.05 mL Log in to see 7 to 9 Days
$345.00
Details
Human Mouse Un-conjugated FACS, IHC, IHC (p), WB 100 μL Log in to see 7 to 9 Days
$507.83
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of BIRC7 (arrow) using rabbit polyclonal BIRC7 Antibody (C-term) (ABIN390073). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the BIRC7 gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 16 Days
$181.73
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with BIRC7 antibody ABIN214412 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-BIRC7 / Livin antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Log in to see 11 to 14 Days
$484.00
Details

Top referenced anti-Baculoviral IAP Repeat-Containing 7 Antibodies

  1. Human Monoclonal BIRC7 Primary Antibody for ICC, IF - ABIN252506 : Nachmias, Ashhab, Bucholtz, Drize, Kadouri, Lotem, Peretz, Mandelboim, Ben-Yehuda: Caspase-mediated cleavage converts Livin from an antiapoptotic to a proapoptotic factor: implications for drug-resistant melanoma. in Cancer research 2003 (PubMed)
    Show all 21 Pubmed References

  2. Human Polyclonal BIRC7 Primary Antibody for IHC (p), IP - ABIN252145 : Liu, Kong, Zeng, Liu, Bi, Jiang, Han: Livin may serve as a marker for prognosis of bladder cancer relapse and a target of bladder cancer treatment. in Urologic oncology 2009 (PubMed)
    Show all 5 Pubmed References

  3. Human Monoclonal BIRC7 Primary Antibody for WB - ABIN2668574 : Jiang, Zhou, Yuen, Corless, Heinrich, Fletcher, Demetri, Widlund, Fisher, Hodi: Imatinib targeting of KIT-mutant oncoprotein in melanoma. in Clinical cancer research : an official journal of the American Association for Cancer Research 2008 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal BIRC7 Primary Antibody for ELISA, WB - ABIN268739 : Schatton, Schütte, Frank, Zhan, Hoerning, Robles, Zhou, Hodi, Spagnoli, Murphy, Frank: Modulation of T-cell activation by malignant melanoma initiating cells. in Cancer research 2010 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal BIRC7 Primary Antibody for ELISA, WB - ABIN2475343 : Vucic, Deshayes, Ackerly, Pisabarro, Kadkhodayan, Fairbrother, Dixit: SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP). in The Journal of biological chemistry 2002 (PubMed)

  6. Human Polyclonal BIRC7 Primary Antibody for IF (p), IHC (p) - ABIN672561 : Zhang, Peng, Luo, Zhou: Prospective experimental studies on the renal protective effect of ulinastatin after paraquat poisoning. in World journal of emergency medicine 2014 (PubMed)

  7. Human Polyclonal BIRC7 Primary Antibody for ELISA, WB - ABIN3043512 : Guo, Gao, Zhang, Jing, Liu, Shi, Zhai, Jing, Du: Expression and clinical significance of livin protein in hepatocellular carcinoma. in Disease markers 2014 (PubMed)

More Antibodies against Baculoviral IAP Repeat-Containing 7 Interaction Partners

Human Baculoviral IAP Repeat-Containing 7 (BIRC7) interaction partners

  1. The overexpression of PTEN concomitant with Livin gene silencing was confirmed as a feasible and effective in vitro and in vivo gene modulation method, which may represent a potential therapeutic strategy for the treatment of Gastric Cancer.

  2. Livin overexpression not only significantly inhibited RCC (show XRCC1 Antibodies) cell apoptosis and increased cell viability, but completely reversed the si-CCAT1-mediated repression of cell viability

  3. our results revealed that Livin induced EMT through the activation of the p38/GSK3beta pathway, which in turn promoted the progression and metastasis of breast cancer, especially for triple-negative breast cancer (TNBC)

  4. our results suggest that siRNA-mediated Livin knockdown enhanced the chemosensitivity of the three head and neck squamous cell carcinoma cell lines to cisplatin, 5-FU and docetaxel.

  5. Livin is specifically over-expressed in adrenocortical carcinoma.

  6. Further experiments confirmed the induction of cell apoptosis and suppression of cell proliferation by anti-MM scFv-tP in LiBr cells, along with efficient silence of Livin gene both in vitro and in vivo. Altogether, our findings provide a feasible approach to transport Livin small interfering RNA to malignant melanoma cells which would be a new therapeutic strategy for combating malignant melanoma

  7. MicroRNA-214 inhibits the osteogenic differentiation of human osteoblasts through the direct regulation of BIRC7.

  8. the results of the present study suggested that Livin may enhance tumorigenesis by modulating the mitogenactivated/Akt (show AKT1 Antibodies) signaling pathways in human HSCC.

  9. Positive BIRC7 expression and negative KLF4 (show KLF4 Antibodies) expression are associated with the progression of PDAC and poor prognosis in patients with PDAC.

  10. High expression of BIRC7 is associated with drug resistance in Renal cell carcinoma (show MOK Antibodies).

Mouse (Murine) Baculoviral IAP Repeat-Containing 7 (BIRC7) interaction partners

  1. The overexpression of PTEN concomitant with Livin gene silencing was confirmed as a feasible and effective in vitro and in vivo gene modulation method, which may represent a potential therapeutic strategy for the treatment of Gastric Cancer.

  2. Data showed that Livin knock-down suppressed cell proliferation and inhibited cell invasion, accompanied by downregulation of VEGF (show VEGFA Antibodies) and MMP-2 (show MMP2 Antibodies)/-9. Its silencing resulted in the prevention of xenograft tumor formation.

  3. Birc7 is a late fiber gene of the mouse lens. Its expression in cells bordering the OFZ is consistent with a role in organelle degradation, a process in which the ubiquitin proteasome pathway has been implicated previously.

  4. ML-IAP is dispensable for both normal mouse development and ocular homoeostasis.

Baculoviral IAP Repeat-Containing 7 (BIRC7) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.

Gene names and symbols associated with BIRC7

  • baculoviral IAP repeat containing 7 (BIRC7) antibody
  • baculoviral IAP repeat containing 7 (birc7) antibody
  • baculoviral IAP repeat-containing 7 (Birc7) antibody
  • baculoviral IAP repeat-containing 7 (livin) (Birc7) antibody
  • baculoviral IAP repeat containing 7 S homeolog (birc7.S) antibody
  • birc7 antibody
  • bird7a antibody
  • E130019N06 antibody
  • EIAP/XLX antibody
  • kiap antibody
  • Livin antibody
  • ml-iap antibody
  • mliap antibody
  • RGD1562883 antibody
  • rnf50 antibody
  • xEIAP antibody
  • xEIAP/XLX antibody
  • xlx antibody
  • zgc:165605 antibody

Protein level used designations for BIRC7

RING finger protein 50 , baculoviral IAP repeat-containing protein 7 , kidney inhibitor of apoptosis protein , livin inhibitor of apoptosis , melanoma inhibitor of apoptosis protein , baculoviral IAP repeat-containing 7 , E3 ubiquitin-protein ligase EIAP , Embryonic/Egg IAP , baculoviral IAP repeat-containing 7 (livin) , E3 ubiquitin-protein ligase EIAP-A , IAP-like protein , XIAP homolog XLX , baculoviral IAP repeat-containing 7 a , baculoviral IAP repeat-containing protein 7 a , baculoviral IAP repeat-containing protein 7-A , embryonic/Egg IAP , inhibitor of apoptosis-like protein

GENE ID SPECIES
79444 Homo sapiens
697671 Macaca mulatta
100127811 Xenopus (Silurana) tropicalis
296468 Rattus norvegicus
485969 Canis lupus familiaris
514508 Bos taurus
100073331 Danio rerio
419239 Gallus gallus
329581 Mus musculus
398387 Xenopus laevis
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