Bone gamma-Carboxyglutamate (Gla) Protein (BGLAP) ELISA Kits

Constitutes 1-2% of the total bone protein. Additionally we are shipping Osteocalcin Antibodies (358) and Osteocalcin Proteins (52) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
BGLAP 632 P02818
BGLAP 12096 P86546
BGLAP 25295 P04640
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Top Osteocalcin ELISA Kits at

Showing 10 out of 126 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse 0.063 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
Rat 6.3 pg/mL 15.6 pg/mL - 1000 pg/mL 96 Tests Log in to see 13 to 16 Days
Human 0.264 ng/mL 0.62 ng/mL - 40 ng/mL 96 Tests Log in to see 13 to 16 Days
Rabbit 0.119 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Log in to see 13 to 16 Days
Pig 0.123 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Log in to see 13 to 16 Days
Monkey 0.39 ng/mL 1.56-100 ng/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
Goat 0.24 ng/mL 0.94-60 ng/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
Chicken 0.67 pg/mL 1.56 pg/mL - 100 pg/mL 96 Tests Log in to see 13 to 16 Days
Cow 32 pg/mL 78 pg/mL - 5000 pg/mL 96 Tests Log in to see 13 to 16 Days
Dog 0.249 ng/mL 0.62 ng/mL - 40 ng/mL 96 Tests Log in to see 13 to 16 Days

Top referenced Osteocalcin ELISA Kits

  1. Mouse (Murine) Osteocalcin ELISA Kit for Sandwich ELISA - ABIN415574 : Xiao, Cui, Li, Shi, Wang, Le, Wang: Dyslipidemic high-fat diet affects adversely bone metabolism in mice associated with impaired antioxidant capacity. in Nutrition (Burbank, Los Angeles County, Calif.) 2011 (PubMed)
    Show all 17 Pubmed References

  2. Rat (Rattus) Osteocalcin ELISA Kit for Sandwich ELISA - ABIN416281 : Alm??an, B?ciu?, B?ciu?, Alm??an, Bran, Oana: Serum changes induced by intramedullar experimental administration of bisphosphonates. in Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2011 (PubMed)
    Show all 17 Pubmed References

  3. Human Osteocalcin ELISA Kit for Sandwich ELISA - ABIN415006 : Cai, Lai, Yang, Hu, Xin, Liu, Sung: Surface engineering of titanium with potassium hydroxide and its effects on the growth behavior of mesenchymal stem cells. in Acta biomaterialia 2010 (PubMed)
    Show all 11 Pubmed References

  4. Rat (Rattus) Osteocalcin ELISA Kit for Sandwich ELISA - ABIN579618 : Abuohashish, Al-Rejaie, Al-Hosaini, Parmar, Ahmed: Alleviating effects of morin against experimentally-induced diabetic osteopenia. in Diabetology & metabolic syndrome 2013 (PubMed)
    Show all 3 Pubmed References

  5. Rabbit Osteocalcin ELISA Kit for Sandwich ELISA - ABIN416018 : Alfotawei, Naudi, Lappin, Barbenel, Di Silvio, Hunter, McMahon, Ayoub: The use of TriCalcium Phosphate (TCP) and stem cells for the regeneration of osteoperiosteal critical-size mandibular bony defects, an in vitro and preclinical study. in Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery 2014 (PubMed)
    Show all 3 Pubmed References

  6. Pig (Porcine) Osteocalcin ELISA Kit for Sandwich ELISA - ABIN415860 : Tomaszewska, Dobrowolski, Wydrych: Postnatal administration of 2-oxoglutaric acid improves articular and growth plate cartilages and bone tissue morphology in pigs prenatally treated with dexamethasone. in Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2012 (PubMed)
    Show all 3 Pubmed References

  7. Rat (Rattus) Osteocalcin ELISA Kit for Sandwich ELISA - ABIN5524089 : Mohamad, Soelaiman, Chin: Effects of tocotrienol from Bixa orellana (annatto) on bone histomorphometry in a male osteoporosis model induced by buserelin. in Biomedicine & pharmacotherapy 2018 (PubMed)
    Show all 2 Pubmed References

  8. Mouse (Murine) Osteocalcin ELISA Kit for Sandwich ELISA - ABIN1116314 : Niu, Kong, Li, Fan, Pan, Li, Wu, Lu, Mei: Radix Dipsaci total saponins stimulate MC3T3-E1 cell differentiation via the bone morphogenetic protein-2/MAPK/Smad-dependent Runx2 pathway. in Molecular medicine reports 2015 (PubMed)
    Show all 2 Pubmed References

  9. Human Osteocalcin ELISA Kit for Sandwich ELISA - ABIN1116313 : Ma, Liu, Wang, Zhang: Neuropeptide Y, substance P, and human bone morphogenetic protein 2 stimulate human osteoblast osteogenic activity by enhancing gap junction intercellular communication. in Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2015 (PubMed)
    Show all 2 Pubmed References

  10. Human Osteocalcin ELISA Kit for Competition ELISA - ABIN510507 : Feng, Jiang, Zhang, Wang, Zhang, Zhang, Chen, Fan, Tian, Jia: Comparisons of thyroid hormone, intelligence, attention, and quality of life in children with obstructive sleep apnea hypopnea syndrome before and after endoscopic adenoidectomy. in BioMed research international 2015 (PubMed)

More ELISA Kits for Osteocalcin Interaction Partners

Human Bone gamma-Carboxyglutamate (Gla) Protein (BGLAP) interaction partners

  1. there is no significant difference in circulating OPG and OCN levels between RA patients and OA patients. However, plasma/serum OPN level is significantly higher in RA patients compared with OA patients.

  2. The present study has concluded that obesity is an undesirable factor for bone metabolism by reducing serum osteocalcin and by increasing hs-CRP and PTH which contribute to bone resorption.

  3. Osteocalcin plays an important role in glucose and lipid metabolism for protection against nonalcoholic fatty liver disease occurrence and progression.

  4. OCN levels were inversely correlated with body fat parameters and obesity.

  5. Serum osteocalcin level was not independently associated with blood pressure in a Chinese population

  6. The results of this study suggest that serum osteocalcin is associated with the onset of puberty in girls.

  7. The correlation between Mycobacterium avium subsp. paratuberculosis (MAP) infection and elevation of sera ucOC, reduction of active osteocalcin and increased calcium supports MAP infection role in Crohn's disease and complications with osteoporosis.

  8. The results showed no significant correlation between osteocalcin HindIII gene polymorphism and bone mineral density (BMD) and therefore osteocalcin HindIII gene polymorphism may not have major effects on BMD variation in postmenopausal North Indian women.

  9. Decreased circulating carboxylated osteocalcin is associated with low-energy bone fractures in children.

  10. a decrease in serum osteocalcin levels is associated with future development of type 2 diabetes mellitus.

  11. Findings from the available data indicated an overall significant inverse association between serum osteocalcin and body mass index--{REVIEW}

  12. relatively lower serum osteocalcin levels were associated with a higher risk of MACE in Chinese men with CAD

  13. undercarboxylated form of osteocalcin in serum not related significantly to semen parameters or measured hormones in male infertility

  14. serum level not correlated with gender, race/ethnicity, age, diabetes type, BMI percentile, random C-peptide, glucose, or HbA1c at pediatric diabetes diagnosis; serum level inversely correlated with HbA1c at first office visit following diagnosis

  15. Serum osteocalcin was directly and independently correlated with circulating uric acid in a population of healthy obese subjects.

  16. gamma-carboxylation of OCN on Glu17 residue correlates with insulin resistance and subclinical inflammation, suggesting that gamma-carboxylation of OCN negatively regulates its endocrine action

  17. There were differences in the associations between total osteocalcin and glucose metabolism in Han and Uygur T2DM patients, indicating genetic factors may play a role in modulating OC and glucose metabolism in different ethnic population.

  18. The study demonstrated that undercarboxylated osteocalcin (ucOC) is related to 25(OH)D and adiponectin concentrations. Both ucOC and 25(OH)D were lower in overweight and obese adolescents.

  19. Increased advanced glycation end products and protein oxidative damage markers in the course of obesity may contribute to decreased carboxylated osteocalcin serum level.

  20. Progressive calcification of atherosclerotic plaques is accompanied by insignificant accumulation of calcitonin and osteoprotegerin, whereas the osteocalcin expression significantly increased during calcification.

Mouse (Murine) Bone gamma-Carboxyglutamate (Gla) Protein (BGLAP) interaction partners

  1. expression in offspring bone not changed by maternal high fat diet

  2. the uncarboxylated form of osteocalcin does not trigger Akt phosphorylation and glucose uptake by itself but promotes insulin-induced glucose uptake in myotubes, probably by up-regulating Akt signaling through ERK activation

  3. The Twist2-Cre, Osterix-Cre and osteocalcin-Cre lines to generate conditional beta1 integrin deletions, were used to investigate the role of beta1 integrins on skeletal phenotype.

  4. OCN is gamma-carboxylated by the gamma-carboxylase (GGCX) on three glutamic acid residues, a cellular process requiring reduction of vitamin K by a second enzyme, VKORC1.

  5. results showed an increase in the expression of Cbfa1 and OCN in fibroblasts and osteoblasts exposed to fluoride.

  6. Data indicate that Ca2+ binding triggered a similar conformational transition in both gamma-carboxyglutamic acid-containing protein osteocalcin (Gla-OCN) and Glu-OCN from a disordered structure to a more compact/stable form.

  7. In primary adipocytes, both carboxylated and uncarboxylated osteocalcin increased basal and insulin-stimulated glucose transport.

  8. Taken together, these findings demonstrate that SMILE negatively regulates osteocalcin via a direct interaction with RUNX2

  9. Osteoblast-specific expression of Fra-2/AP-1 controls adiponectin and osteocalcin expression and affects metabolism.

  10. contribution of OC-OPN to fracture toughness is related to their presence at the extrafibrillar organic-mineral interfaces

  11. Insulin resistance in osteoblasts led to a decrease in circulating levels of the active form of osteocalcin, thereby decreasing insulin sensitivity in skeletal muscle.

  12. loss of osteocalcin/Gprc6a signaling has a profound effect on beta-cell mass accrual during late pancreas morphogenesis

  13. This study reveals that the skeleton via osteocalcin influences cognition and contributes to the maternal influence on fetal brain development.

  14. T3 stimulates the activation of Rho-kinase in osteoblasts, which functions as a negative regulator of T3-stimulated osteocalcin synthesis

  15. Uncarboxylated osteocalcin acts via Gprc6a to induce GLP-1 release from the gut; the stimulatory effect of uncarboxylated osteocalcin on insulin secretion is largely mediated by GLP-1.

  16. These results indicate that PP2A Calpha and its activity play a negative role in osteoblast differentiation and Osterix is a key factor responsible for regulating the expressions of Bsp and OCN during PP2A Calpha-mediated osteoblast differentiation.

  17. alphaNAC interacts with histone deacetylase corepressors to control Myogenin and Osteocalcin gene expression.

  18. Data from TR4 (steroid/thyroid hormone receptor 4) knockout mice suggest that TR4 binds to promoter region of osteocalcin gene and induces osteocalcin expression; this interaction maintains osteoblast activity during bone development/remodeling.

  19. Alterations of responses in knockout mice that suggest participation of osteocalcin in transmission of information about those sensory stimuli.

  20. BMP2 induces osteoblast differentiation through Runx2-dependent ATF6 expression, which directly regulates Oc transcription.

Cow (Bovine) Bone gamma-Carboxyglutamate (Gla) Protein (BGLAP) interaction partners

  1. Osteopontin, osteocalcin and OB-cadherin expression in Synthetic nanohydroxyapatite vs bovine hydroxyapatite cultured Osteoblastic-like cells.

  2. Data suggest that helical content of 3 Glu-OCN is 57% and is independent of calcium binding; 3 Glu-OCN contains 3 alpha-helices around a hydrophobic core; study includes first high-resolution structure of bovine 3 Glu-OCN using X-ray crystallography.

  3. Serum osteocalcin levels in non-periparturient Holstein dairy cows were highest in the youngest cows, decreasing with age until time of first calving. In periparturient cows, serum osteocalcin levels were higher in primiparous than in multiparous cows.

  4. Osteocalcin is released from the bone matrix during bone resorption as intact molecules and fragments; serum osteocalcin should be considered as a marker of bone turnover rather than bone formation

  5. A molecular mechanism of lead toxicity for calcium binding proteins.

Zebrafish Bone gamma-Carboxyglutamate (Gla) Protein (BGLAP) interaction partners

  1. In zebrafish, bgp and mgp mRNAs were localized in all mineralized tissues during and after calcification including bone and calcified cartilage of branchial arches.

Osteocalcin (BGLAP) Antigen Profile

Antigen Summary

Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.

Gene names and symbols associated with BGLAP

  • bone gamma-carboxyglutamate protein (BGLAP) antibody
  • bone gamma carboxyglutamate protein (Bglap) antibody
  • bone gamma-carboxyglutamate protein (Bglap) antibody
  • bone gamma-carboxyglutamate protein S homeolog (bglap.S) antibody
  • bone gamma-carboxyglutamate (gla) protein (bglap) antibody
  • osteocalcin (ocn) antibody
  • bone gamma-carboxyglutamate (gla) protein (BGLAP) antibody
  • bone gamma-carboxyglutamate protein (bglap) antibody
  • osteocalcin (LOC100529177) antibody
  • polyamine-modulated factor 1 (LOC100146589) antibody
  • BGLAP antibody
  • Bglap1 antibody
  • Bglap2 antibody
  • bgp antibody
  • Bgpr antibody
  • Bgpra antibody
  • GLA antibody
  • LOC792433 antibody
  • mOC-A antibody
  • OC antibody
  • ocn antibody
  • OG1 antibody
  • PMF1 antibody

Protein level used designations for BGLAP

bone Gla protein , bone gamma-carboxyglutamate (gla) protein (osteocalcin) , gamma-carboxyglutamic acid-containing protein , osteocalcin , BGP , bone gamma carboxyglutamate protein 1 , bone Gla-protein , bone gamma-carboxyglutamate protein 2 , bone gamma-carboxyglutamic acid (Gla) protein (osteocalcin) , xBGP , osteocalcin preproprotein , hypothetical protein LOC792433 , bone gamma-carboxyglutamate protein osteocalcin , Bone Gla protein , Gamma-carboxyglutamic acid-containing protein , Osteocalcin , bone gamma-carboxyglutamate (gla) protein , polyamine-modulated factor 1

632 Homo sapiens
12096 Mus musculus
25295 Rattus norvegicus
281646 Bos taurus
396348 Gallus gallus
397530 Sus scrofa
399370 Xenopus laevis
677670 Ovis aries
718296 Macaca mulatta
792433 Danio rerio
100136174 Oncorhynchus mykiss
100190891 Pan troglodytes
100192339 Salmo salar
100529177 Oryzias latipes
100534506 Oreochromis niloticus
100735766 Cavia porcellus
403762 Canis lupus familiaris
101085947 Felis catus
100861188 Capra hircus
100340503 Oryctolagus cuniculus
100146589 Equus caballus
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