CCHC-Type Zinc Finger, Nucleic Acid Binding Protein Proteins (CNBP)

CNBP encodes a nucleic-acid binding protein with seven zinc-finger domains. Additionally we are shipping CNBP Antibodies (107) and CNBP Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CNBP 7555 P62633
CNBP 64530 P62634
CNBP 12785 P53996
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Top CNBP Proteins at antibodies-online.com

Showing 8 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$547.80
Details
Escherichia coli (E. coli) Human His-SUMO Tag   100 μg Log in to see 11 Days
$411.40
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,388.83
Details
Yeast Chicken His tag   1 mg Log in to see 60 to 71 Days
$2,398.00
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,410.83
Details

CNBP Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Rat (Rattus)

Mouse (Murine)

Top referenced CNBP Proteins

  1. Human CNBP Protein expressed in Wheat germ - ABIN1349806 : Raheem, Olufemi, Bachinski, Vihola, Sirito, Holmlund-Hampf, Haapasalo, Li, Udd, Krahe: Mutant (CCTG)n expansion causes abnormal expression of zinc finger protein 9 (ZNF9) in myotonic dystrophy type 2. in The American journal of pathology 2010 (PubMed)

More Proteins for CCHC-Type Zinc Finger, Nucleic Acid Binding Protein (CNBP) Interaction Partners

Human CCHC-Type Zinc Finger, Nucleic Acid Binding Protein (CNBP) interaction partners

  1. The authors report a previously unknown long noncoding RNA which, together with CNBP, is involved in the fine-tuned regulation of CCND1 (show CCND1 Proteins) mRNA stability, without which CCND1 (show CCND1 Proteins) exhibits, at most, partial expression.

  2. [CCTG (show CCT3 Proteins)]n repeat expansion, differently from the DM1 (show DMPK Proteins) mutation, does not influence the methylation status of the CNBP gene and other molecular mechanisms are involved in the pathogenesis of Myotonic Dystrophy type 2..

  3. RNA sequence preferences of unconventional RNA-binding proteins, Nudt21 (show NUDT21 Proteins) and CNBP, has been described.

  4. A second point is that DM mutations, although located in noncoding regions, may reduce the expression of mutant alleles, raising questions whether loss-of-function may contribute to the phenotype, or possibly impose a safety limit on knockdown therapies that create or aggravate a DMPK (show DMPK Proteins) or CNBP deficiency state

  5. CNBP is supporting translation by resolving stable structures on mRNAs.

  6. A G-rich motif in the lncRNA Braveheart interacts with Cnbp to specify the cardiovascular lineage.

  7. The cnbp overexpression rescued the Treacher Collins Syndrome phenotype in a dose-dependent manner by a reactive oxygen species-cytoprotective action that prevented the redox-responsive genes' upregulation but did not normalize the synthesis of ribosomal RNAs.

  8. High CNBP expression is associated with Medulloblastoma.

  9. CNBP overexpression caused increase of cell death and suppression of cell metastasis through its induction of G-quadruplex formation in the promoter of hnRNP K (show HNRNPK Proteins) resulting in hnRNP K (show HNRNPK Proteins) down-regulation

  10. Arginine methylation of CNBP in the RG motif does not change the subcellular localization but regulates its RNA binding activity.

Mouse (Murine) CCHC-Type Zinc Finger, Nucleic Acid Binding Protein (CNBP) interaction partners

  1. A G-rich motif in the lncRNA Braveheart interacts with Cnbp to specify the cardiovascular lineage.

  2. data support a role for CNBP as a critical transcription factor and a key regulator of the prolonged expression of sustained cytokine IL-6 (show IL6 Proteins) during persistent LPS (show TLR4 Proteins) stimulation or Gram-negative bacterial infection

  3. CNBP up-regulates tbx2b and smarca5 (show SMARCA5 Proteins), and down-regulates wnt5b (show WNT5B Proteins) gene expression.

  4. expression of APP (show APP Proteins)(Swe) in murine tissue induces a decrease in CNBP expression.

  5. CNBP targets Myc (show MYC Proteins) in rostral head formation, is essential for forebrain induction and specification.

CNBP Protein Profile

Protein Summary

This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CNBP

  • cellular nucleic acid-binding protein (ANI_1_1316064)
  • cellular nucleic acid-binding protein (AOR_1_1792194)
  • cellular nucleic acid-binding protein (PTRG_02341)
  • cellular nucleic acid-binding protein (PTRG_04792)
  • zinc finger protein Byr3 (SJAG_02043)
  • cellular nucleic acid-binding protein (VDBG_00279)
  • cellular nucleic acid-binding protein (VDBG_00590)
  • CCHC-type zinc finger nucleic acid binding protein (CNBP)
  • CCHC-type zinc finger, nucleic acid binding protein (Cnbp)
  • CCHC-type zinc finger nucleic acid binding protein L homeolog (cnbp.L)
  • cellular nucleic acid binding protein (Cnbp)
  • AA408710 protein
  • An07g10270 protein
  • cnbp1 protein
  • cnbpa protein
  • dm2 protein
  • promm protein
  • rnf163 protein
  • xcnbp protein
  • zcchc22 protein
  • znf9 protein

Protein level used designations for CNBP

cellular nucleic acid-binding protein , zinc finger protein 9 , cellular nucleic acid binding protein , erythroid differentiation-related , sterol regulatory element-binding protein , zinc finger protein 273 , zinc finger protein 9 (a cellular retroviral nucleic acid binding protein) , cellular nucleic acid binding protein 1 , cellular nucleic acid binding protein a , DNA binding protein

GENE ID SPECIES
4982296 Aspergillus niger CBS 513.88
5988418 Aspergillus oryzae RIB40
6340586 Pyrenophora tritici-repentis Pt-1C-BFP
6343034 Pyrenophora tritici-repentis Pt-1C-BFP
7047891 Schizosaccharomyces japonicus yFS275
9528787 Verticillium alfalfae VaMs.102
9534044 Verticillium alfalfae VaMs.102
100173703 Pongo abelii
7555 Homo sapiens
64530 Rattus norvegicus
476518 Canis lupus familiaris
399294 Xenopus laevis
504831 Bos taurus
395731 Gallus gallus
12785 Mus musculus
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