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The protein encoded by CD163 is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. Additionally we are shipping CD163 Antibodies (411) and CD163 Proteins (16) and many more products for this protein.
Showing 10 out of 71 products:
Human CD163 ELISA Kit for Sandwich ELISA - ABIN1979418
Wang, Yu, Yang, Wu, Zhu, Liu, Liu, Hu, Wu, Xia, Chen: Expression of serum sCD163 in patients with liver diseases and inflammatory disorders. in International journal of clinical and experimental pathology 2015
Show all 2 Pubmed References
Human CD163 ELISA Kit for Sandwich ELISA - ABIN417229
Garcia-Obregon, Azkargorta, Seijas, Pilar-Orive, Borrego, Elortza, Boyano, Astigarraga: Identification of a panel of serum protein markers in early stage of sepsis and its validation in a cohort of patients. in Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2017
Mouse (Murine) CD163 ELISA Kit for Sandwich ELISA - ABIN425050
Mukai, Komatsu, Nakajima, Urai, Nasruddin, Sugama, Nakatani: The effect of 17?-estradiol on cutaneous wound healing in protein-malnourished ovariectomized female mouse model. in PLoS ONE 2014
Human CD163 ELISA Kit for Sandwich ELISA - ABIN578184
Hedegaard, Sellebjerg, Krakauer, Hesse, Bendtzen, Nielsen: Interferon-beta increases systemic BAFF levels in multiple sclerosis without increasing autoantibody production. in Multiple sclerosis (Houndmills, Basingstoke, England) 2011
house dust mite -challenged Cd163-/- mice displayed increases in airway eosinophils and mucous cell metaplasia
In diabetic mice, increased sCD163 at wk 5 and decreased percentage of CD163(+) monocytes at wk 10 preceded alteration in kidney collagen IV mRNA at wk 20. In vitro incubation of monocytes in anti-inflammatory glucocorticoid increased the percentage of CD163(+) monocytes.
During ischaemia, soluble CD163 functions as a decoy receptor for TWEAK (show TNFSF12 ELISA Kits), to regulate TWEAK (show TNFSF12 ELISA Kits)-induced activation of canonical nuclear factor-kappaB and Notch (show NOTCH1 ELISA Kits) signalling necessary for myogenic progenitor cell proliferation.
Data indicate an essential substrate motif for ADAM17 (show ADAM17 ELISA Kits)-mediated CD163 and proTNF-alpha cleavage in macrophages.
alpha(1)-Acid glycoprotein (show ORM1 ELISA Kits) up-regulates CD163 via TLR4 (show TLR4 ELISA Kits)/CD14 protein (show ERGIC2 ELISA Kits) pathway: possible protection against hemolysis-induced oxidative stress.
Data show that telmisartan reduced the mRNA expression of CD11c and TNF-alpha (show TNF ELISA Kits), M1 macrophage markers, and significantly increased the expressions of M2 markers, such as CD163, CD209 (show CD209 ELISA Kits).
Assignment of the CD163 antigen to mouse chromosome 6 band F2.
Expression of CD163 in urinary bladder cancer cells is significantly correlated with macrophage infiltration and might have a tumor promoting impact.
A separate measurement of the two forms of CD163 constituting 'soluble CD163' in plasma may therefore add to the diagnostic and prognostic value.
our results suggest that MR and CD163 may be novel biomarkers for CRC (show CALR ELISA Kits) detection and survival evaluation.
Data suggest a novel pathophysiological role of CD163 in type 2 diabetes; monocyte surface CD163 levels are significantly associated with insulin (show INS ELISA Kits) resistance in patients with type 2 diabetes; the association of insulin (show INS ELISA Kits) resistance with soluble CD163 levels is less significant. This study was conducted in Japan.
Detection of the CD163 antigen on cancer cells might be a useful marker for evaluating the clinical course of patients with clear cell renal cell carcinoma (show MOK ELISA Kits)
CD163-expression by cancer cells was significantly associated with MI and clinicopathological data. Patients with CD163-positive tumors had significantly shorter disease-free survival (DFS (show FST ELISA Kits)) after RT.
Plasma CD163 levels were increased in obese and type 2 diabetes mellitus patients compared to controls.
soluble CD163 is associated with markers of liver necro-inflammation and glucose homoeostasis in non-alcoholic fatty liver disease.
The effect of LPS in the expression of CD163 and CD206 on monocytes is not reverted in LPS tolerant cells, and the inhibition of inflammatory cytokines in tolerant cells is not related with modulation of these receptors
The cumulative incidence of de novo-onset cGVHD was higher in patients with higher plasma soluble CD163 concentrations at day 80 than those with lower concentrations (75% versus 40%, P = .018). The cumulative incidence of de novo- or quiescent-onset cGVHD did not differ statistically according to concentrations of the 3 other proteins at day 80.
Study investigated the association of three CD163 polymorphisms with host immune responses following PRRSV challenge and also analyzed the combined effects of the CD163 SNPs. The most significant associations were found with the c.2509G>C, c.2638A>G and c.3534C>T polymorphisms.
deletion of Exon 7 of the CD163 gene, encoding SRCR5 had no adverse effects in pigs and these animals showed complete resistance to viral infection by the positive-strand RNA PRRS virus
CD163 is not necessary for infection with African swine fever virus.
CD163 represents an additional candidate gene for resistance against porcine reproductive and respiratory syndrome.
Overexpression of ADAM17 (show ADAM17 ELISA Kits) induced downregulation of CD163 expression and a reduction in reproductive and respiratory syndrome virus infection.
Fusion protein of sialoadhesin (show SIGLEC1 ELISA Kits) and domains 5-9 of CD163 receptors blocked the respiratory syndrome virus infection.
GP4 (show CD36 ELISA Kits) is involved in interaction with cellular receptor CD163.
). These results provided fundamental evidence for CD163 and SN as two functional candidate genes affecting immunity in pigs.
Porcine reproductive and respiratory syndrome virus GP4 (show CD36 ELISA Kits) was found to co-localize with CD163 in the lipid rafts on the plasma membrane.
Our results suggest that the intracellular domain of CD163 may be associated with an important yet-unknown function during porcine reproductive and respiratory syndrome virus replication.
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
, CD163 molecule
, scavenger receptor cysteine-rich type 1 protein M130-like
, scavenger receptor cysteine-rich type 1 protein M130
, hemoglobin scavenger receptor
, macrophage-associated antigen