anti-CD276 Molecule (CD276) Antibodies

The protein encoded by CD276 belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Additionally we are shipping CD276 Proteins (45) and CD276 Kits (23) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CD276 102657 Q8VE98
CD276 80381 Q5ZPR3
CD276 315716 Q7TPB4
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Top anti-CD276 Antibodies at antibodies-online.com

Showing 10 out of 223 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated CyTOF, FACS, IHC, SimWes, WB Detection of B7-H3 in PC-3 Human Cell Line by Flow Cytometry. PC-3 human prostate carcinoma cells were stained with Goat Anti-Human B7-H3 Antigen Affinity-purified Polyclonal Antibody. Detection of Human B7-H3 by Simple WesternTM. Simple Western lane view shows lysates of U2OS human osteosarcoma cell line, loaded at 0.2 mg/mL. A specific band was detected for B7-H3 at approximately 120-160 kDa (as indicated) using 10 ug/mL of Goat Anti-Human B7-H3 Antigen Affinity-purified Polyclonal Antibody. This experiment was conducted under reducing conditions and using the 12-230 kDa separation system. 100 μg Log in to see 8 to 9 Days
$433.55
Details
Human Mouse Un-conjugated CyTOF, FACS, WB Detection of B7-H3 in Human Dendritic Cells by Flow Cytometry. Human monocyte-derived dendritic cells were stained with Mouse Anti-Human B7-H3 Monoclonal Antibody. Detection of B7-H3 in PC-3 Human Cell Line by Flow Cytometry. PC-3 human prostate cancer cell line was stained with Mouse Anti-Human B7-H3 Monoclonal Antibody. 100 μg Log in to see 8 to 9 Days
$328.90
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Mouse Liver, antibody was diluted at 1:100. 100 μL Log in to see 16 Days
$181.73
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: CD276 Antibody [NBP1-88966] - Staining of human prostate shows membranous positivity in glandular cells. Immunocytochemistry/Immunofluorescence: CD276 Antibody [NBP1-88966] - Staining of human cell line A-431 shows positivity in vesicles. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated WB Western blot analysis of CD276 expression in MCF7 (A), HEK293T (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Human 293T Cells; Lane2: Human PC-3 Cells; Lane3: Human MCF-7 Cells. 100 μg Log in to see 13 to 16 Days
$316.00
Details
Human Rabbit Un-conjugated ELISA, IP, WB 100 μg Log in to see 20 to 21 Days
$218.90
Details
Human Rabbit Un-conjugated WB CD276 Antibody (C-term) (ABIN656709) western blot analysis in MCF-7 cell line lysates (35 µg/lane). This demonstrates the CD276 antibody detected the CD276 protein (arrow). Overlay histogram showing U-2 OS cells stained with ABIN2845939(green line). The cells were fixed with 2% paraformaldehyde (10 min) and then permeabilized with 90% methanol for 10 min. The cells were then icubated in 2% bovine serum albumin to block non-specific protein-protein interactions followed by the antibody (ABIN2845939, 1:25 dilution) for 60 min at 37ºC. The secondary antibody used was Goat-Anti-Rabbit IgG, DyLight® 488 Conjugated Highly Cross-Adsorbed(1583138) at 1/200 dilution for 40 min at 37ºC. Isotype control antibody (blue line) was rabbit IgG1 (1μg/1x10^6 cells) used under the same conditions. Acquisition of >10, 000 events was performed. Dilution: 1:25 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Mouse Fluorescein FACS Detection of B7-H3 in PC-3 Human Cell Line by Flow Cytometry. PC-3 human prostate cancer cell line was stained with Mouse Anti-Human B7-H3 Fluorescein-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$299.00
Details

Top referenced anti-CD276 Antibodies

  1. Human Polyclonal CD276 Primary Antibody for CyTOF, FACS - ABIN4900125 : Jang, Park, Choi, Kim, Hwang, Baek, Suh, Mun, Suh: 12-O-tetradecanoyl phorbol 13-acetate induces the expression of B7-DC, -H1, -H2, and -H3 in K562 cells. in International journal of oncology 2007 (PubMed)
    Show all 10 Pubmed References

  2. Human Monoclonal CD276 Primary Antibody for CyTOF, FACS - ABIN4900123 : Sucker, Zhao, Real, Heeke, Bielefeld, Maβen, Horn, Moll, Maltaner, Horn, Schilling, Sabbatino, Lennerz, Kloor, Ferrone, Schadendorf, Falk, Griewank, Paschen: Genetic evolution of T-cell resistance in the course of melanoma progression. in Clinical cancer research : an official journal of the American Association for Cancer Research 2014 (PubMed)
    Show all 5 Pubmed References

  3. Human Monoclonal CD276 Primary Antibody for FACS - ABIN2479632 : Montanari, Baraldo, Zara, Benetello, Secchieri, Furlanut: Side effects of imipramine therapy in enuretic children. in Pharmacological research : the official journal of the Italian Pharmacological Society 1991 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal CD276 Primary Antibody for FACS - ABIN2479633 : Chapoval, Ni, Lau, Wilcox, Flies, Liu, Dong, Sica, Zhu, Tamada, Chen: B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production. in Nature immunology 2001 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal CD276 Primary Antibody for IHC (fro), FACS - ABIN2479631 : Sun, Vale, Leung, Kanwar, Gupta, Krissansen: Mouse B7-H3 induces antitumor immunity. in Gene therapy 2003 (PubMed)
    Show all 4 Pubmed References

  6. Human Monoclonal CD276 Primary Antibody for FACS - ABIN2479635 : Ma, Luo, Qiao, Dong, Pan, Jiang, Krissansen, Sun: Complete eradication of hepatocellular carcinomas by combined vasostatin gene therapy and B7H3-mediated immunotherapy. in Journal of hepatology 2006 (PubMed)
    Show all 4 Pubmed References

  7. Human Monoclonal CD276 Primary Antibody for FACS, IHC - ABIN969018 : Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ... in Genome research 2004 (PubMed)
    Show all 2 Pubmed References

  8. Human Monoclonal CD276 Primary Antibody for FACS - ABIN4897213 : Niehage, Steenblock, Pursche, Bornhäuser, Corbeil, Hoflack: The cell surface proteome of human mesenchymal stromal cells. in PLoS ONE 2011 (PubMed)
    Show all 2 Pubmed References

  9. Mouse (Murine) Monoclonal CD276 Primary Antibody for Func, FACS - ABIN2479646 : Ohgo, Nakatsuru, Ishikawa, Matsukura: Interleukin-1 (IL-1) stimulates the release of corticotropin-releasing factor (CRF) from superfused rat hypothalamo-neurohypophyseal complexes (HNC) independently of the histaminergic mechanism. in Brain research 1992 (PubMed)
    Show all 2 Pubmed References

  10. Mouse (Murine) Monoclonal CD276 Primary Antibody for FACS - ABIN2479637 : Nagashima, Harada, Usui, Yamazaki, Yagita, Okumura, Takahashi, Akiba: B7-H3 contributes to the development of pathogenic Th2 cells in a murine model of asthma. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)

More Antibodies against CD276 Interaction Partners

Cow (Bovine) CD276 Molecule (CD276) interaction partners

  1. Anterior pituitary gland progenitor cells containing 4Ig-B7-H3 (CD276) may play a critical role in the immunoendocrine network.

Mouse (Murine) CD276 Molecule (CD276) interaction partners

  1. These results demonstrate that B7H3 substantially ameliorates LPS (show TLR4 Antibodies)-induced Acute lung injury and this protection afforded by B7H3 is predominantly associated with its inhibitory effect on pulmonary PMN (show TBCE Antibodies) migration and infiltration

  2. Inhibition of the B7-H3 immune checkpoint limits tumor growth by enhancing cytotoxic lymphocyte function

  3. blockage of NF-kappaB (show NFKB1 Antibodies) p65 (show NFkBP65 Antibodies) and/or MAPK p38 (show MAPK1 Antibodies) with their specific inhibitors strongly attenuated B7-H3-amplified inflammatory response with significantly reduced proinflammatory cytokine and chemokine (show CCL1 Antibodies) production, and markedly ameliorated B7-H3-exacerbated disruption of blood-brain barrier and severity of disease status in S. pneumoniae-infected mice.

  4. CD276 is broadly expressed by tumor cells and tumor vasculature but Is dispensable for tumor growth.

  5. this study shows that B7-H3 participates in the development of acute pancreatitis

  6. Data show that B7-H3 protein is over-expressed in cerulein-induced acute pancreatitis, and anti-B7-H3 monoclonal antibody can attenuate the inflammation and alleviate the injury of pancreas and lung tissues.

  7. Ablation of B7-H3 but Not B7-H4 (show VTCN1 Antibodies) Results in Highly Increased Tumor Burden in a Murine Model of Spontaneous Prostate Cancer

  8. Murine B7-H3 is a positive co-stimulatory molecule in the regulation of T cell-mediated immune responses.

  9. B7-H3 inhibits T cell proliferation. FG loop of the IgV domain plays a critical role in this function. B7-H3 crystallized as an unusual dimer arising from the exchange of the G strands in the IgV domains of partner molecules

  10. The study investigates the role of B7-H3 in pancreatic cancer progression and shows that this protein promotes cancer cell migration and invasiveness in vitro and in vivo.

Human CD276 Molecule (CD276) interaction partners

  1. High B7-H3 expression is associated with cervical cancer invasiveness.

  2. IDH1 (show IDH1 Antibodies) and B7H3 cannot be used as independent prognostic factors, co-expression of IDH1 (show IDH1 Antibodies) and B7H3 significantly correlated with the prognosis of CRC (show CALR Antibodies) patients and may serve as a combined predictive marker. Thus, the correlation between IDH1 (show IDH1 Antibodies) and B7H3 has been proven in vivo and in vitro.

  3. Our findings revealed that B7-H3 affect ovarian cancer progression through the Jak2 (show JAK2 Antibodies)/Stat3 (show STAT3 Antibodies) pathway, indicating that B7-H3 has the potential to be a useful prognostic marker.

  4. B7-H3 protein is expressed in the majority of NSCLCs and is associated with smoking history. High levels of B7-H3 protein have a negative prognostic impact in lung carcinomas. Coexpression of B7-H3 with PD-L1 (show CD274 Antibodies) and B7-H4 (show VTCN1 Antibodies) is relatively low, suggesting a nonredundant biological role of these targets.

  5. metastatic melanoma cells with knockdown expression of B7-H3 showed modest decrease in proliferation and glycolytic capacity.

  6. results suggest that B7-H3 may be a valuable biomarker in determining tumor progression and prognosis of intrahepatic cholangiocarcinoma

  7. these results demonstrate that sB7-H3 promotes invasion and metastasis through the TLR4 (show TLR4 Antibodies)/NF-kappaB (show NFKB1 Antibodies) pathway in pancreatic carcinoma

  8. Inhibition of the B7-H3 immune checkpoint limits tumor growth by enhancing cytotoxic lymphocyte function

  9. Higher B7-H3 expression correlates with Gleason grade, prostate cancer stage and poor oncologic outcomes in prostatectomy cohorts. B7-H3 expression appears to be related to androgen signaling as well as the immune reactome.

  10. Study reportes that B7-H3 and B7-H4 (show VTCN1 Antibodies) are highly expressed in human esophageal cancer tissues and significantly associated with tumor invasion.

CD276 Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-CD276 Molecule (CD276) Antibodies

  • CD276 molecule (CD276) antibody
  • CD276 molecule S homeolog (cd276.S) antibody
  • CD276 molecule (cd276) antibody
  • CD276 antigen (Cd276) antibody
  • Cd276 molecule (Cd276) antibody
  • 4Ig-B7-H3 antibody
  • 6030411F23Rik antibody
  • AU016588 antibody
  • B7-H3 antibody
  • B7H3 antibody
  • B7RP-2 antibody
  • sc:d0645 antibody
  • zgc:158279 antibody

Protein level used designations for anti-CD276 Molecule (CD276) Antibodies

CD276 molecule , CD276 antigen-like , CD276 antigen homolog , CD276 antigen , B7 homolog 3 , B7-H3 , costimulatory molecule

GENE ID SPECIES
100471106 Ailuropoda melanoleuca
447379 Xenopus laevis
467818 Pan troglodytes
487638 Canis lupus familiaris
508656 Bos taurus
699877 Macaca mulatta
791140 Danio rerio
100195762 Salmo salar
100397167 Callithrix jacchus
100446767 Pongo abelii
102657 Mus musculus
415315 Gallus gallus
80381 Homo sapiens
315716 Rattus norvegicus
Selected quality suppliers for anti-CD276 (CD276) Antibodies
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