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CDC42EP3 encodes a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB (Cdc42, Rac interactive binding) domain. Additionally we are shipping CDC42EP3 Antibodies (41) and CDC42EP3 Proteins (5) and many more products for this protein.
Results provide evidence that Cdc42EP3 function in cancer-associated fibroblasts relies on tight regulation by Cdc42 (show CDC42 ELISA Kits).
Studies indicate some of the functional and mechanistic roles of the binder of Rho GTPases Borg1 (show CDC42EP2 ELISA Kits)-5 proteins (Cdc42EP1 (show CDC42EP1 ELISA Kits)-5), including cytoskeletal remodelling and signalling.
The expression of CDC42EP3 mRNA was significantly increased by 19.7% in dorsal prefrontal cortex in patient with schizophrenia.
This gene encodes a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB (Cdc42, Rac interactive binding) domain. Members of this family of proteins act as effectors of CDC42 function. The encoded protein is involved in actin cytoskeleton re-organization during cell shape changes, including pseudopodia formation. A pseudogene of this gene is found on chromosome 19. Alternative splicing results in multiple transcript variants.
CDC42 effector protein (Rho GTPase binding) 3
, cdc42 effector protein (Rho GTPase binding) 3
, cdc42 effector protein 3
, Cdc42 effector protein 3
, CRIB-containing BORG2 protein
, MSE55-related Cdc42-binding protein
, MSE55-related protein
, binder of Rho GTPases 2