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CDw75 encodes a member of glycosyltransferase family 29.
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This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described.
B-cell antigen CD75
, CMP-N-acetylneuraminate beta-galactosamide alpha-2,6-sialyltransferase
, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1
, ST6Gal I
, alpha 2,6-ST 1
, beta-galactoside alpha-2,6-sialyltransferase 1
, sialyltransferase 1 (beta-galactoside alpha-2,6-sialyltransferase)