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PPIases accelerate the folding of proteins (By similarity). Additionally we are shipping Cwc27 Antibodies (37) and many more products for this protein.
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CWC27 overexpression is associated with Bladder Cancer.
By whole-exome sequencing, recessive protein-truncating mutations in CWC27 were found in seven unrelated families that show a range of clinical phenotypes, including retinal degeneration, brachydactyly, craniofacial abnormalities, short stature, and neurologic defects.
The crystal structure of a relatively protease-resistant N-terminal fragment of human Cwc27 containing the cyclophilin-type peptidyl-prolyl cis-trans isomerase (show PPIL4 Proteins) domain was determined at 2.0 A resolution.
Cwc27 mutant mice have significant embryonic lethality and severe phenotypes in the complete knockout mice while mice with a partial loss-of-function allele mimic the isolated retinal degeneration phenotype.
PPIases accelerate the folding of proteins (By similarity).
, peptidyl-prolyl cis-trans isomerase CWC27 homolog
, peptidyl-prolyl cis-trans isomerase SDCCAG10
, PPIase SDCCAG10
, antigen NY-CO-10
, serologically defined colon cancer antigen 10