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anti-Calcium Binding tyrosine-(Y)-phosphorylation Regulated (CABYR) Antibodies

To reach fertilization competence, spermatozoa undergo a series of morphological and molecular maturational processes, termed capacitation, involving protein tyrosine phosphorylation and increased intracellular calcium. Additionally we are shipping Calcium Binding tyrosine-(Y)-phosphorylation Regulated Proteins (6) and Calcium Binding tyrosine-(Y)-phosphorylation Regulated Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CABYR 686189  
CABYR 26256 O75952
CABYR 71132 Q9D424
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Top anti-Calcium Binding tyrosine-(Y)-phosphorylation Regulated Antibodies at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of CBP86 expression in HepG2 (A), HeLa (B), SP2/0 (C), PC12 (D) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of CABYR using NIH-3T3 whole cell lysates 100 μL 11 to 12 Days
$390.77
Details
Human Mouse Un-conjugated WB Western Blot analysis of CABYR expression in transfected 293T cell line by CABYR MaxPab polyclonal antibody.Lane 1: CABYR transfected lysate(41.10 KDa).Lane 2: Non-transfected lysate. 50 μg 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated WB   100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB   100 μL 11 to 14 Days
$375.83
Details
Human Rabbit Un-conjugated WB   100 μL 11 to 14 Days
$581.17
Details
Human Rabbit Un-conjugated ELISA, IHC, WB   100 μg 13 to 16 Days
$407.69
Details
Human Rabbit Un-conjugated IHC, WB   100 μL 11 to 16 Days
$743.29
Details

More Antibodies against Calcium Binding tyrosine-(Y)-phosphorylation Regulated Interaction Partners

Human Calcium Binding tyrosine-(Y)-phosphorylation Regulated (CABYR) interaction partners

  1. Study of (Co-IP) and reverse co-immunoprecipitation (Co-IP) of CBP86-IV (TSCBP86-IV or CABYR) in human sperm cell lysate identified phosphoglycerate kinase 2 (PGK2) as interacting partner of CABYR. Protein interactions were further confirmed by yeast two-hybrid system.

  2. There is downregulation of both ROPN1 and CABYR in asthenozoospermic samples and importantly, a positive correlation between the expression of the two genes, suggesting that ROPN1 and CABYR co-expression is a prerequisite for normal flagellar function and sperm motility.

  3. Low CABYR expression is associated with colon cancer.

  4. The results demonstrate that depletion of CABYR-a/b sensitizes lung cancer cells to TRAIL-induced apoptosis through YAP/p73-mediated DR5 upregulation.

  5. Short hairpin RNA-mediated knockdown of CABYR-a/b significantly inhibited the proliferation of NCI-H460 and A549 cells and resulted in the attenuation of Akt phosphorylation, which is constitutively active in lung cancer cells.

  6. CABYR-c is highly expressed in hepatocellular carcinoma tissues and may play an oncogenic role in heptocarcinogenesis as well as its progression.

  7. CABYR variants form a complex not only with the scaffolding protein AKAP3 but also with another RII-like domain-containing protein in the sperm fibrous sheath.

  8. High CABYR is associated with neoplasms.

  9. The expression of NF-kappaB was not significantly affected by silencing CABYR in 293T cells.

  10. sequencing, cloning, expression and characterization

  11. Northern blot showed that CABYR transcripts were expressed more distinctly in the fetal brain than in the adult brain, suggesting that this protein may play a role during brain development.

  12. splice variants containing CR-B are expressed during spermiogenesis and assemble into the fibrous sheath of the principal piece; however, calcium binding occurs only to those CABYR isoforms containing CABYR-A

Mouse (Murine) Calcium Binding tyrosine-(Y)-phosphorylation Regulated (CABYR) interaction partners

  1. it is the role of CABYR in the formation of the fibrous sheath that is essential for male fertility.

  2. CABYR expresses at the late stage of spermiogenesis and its isoforms oligomerize and bind with AKAPs and ropporin; which suggests that CABYR participates in the assembly of the fibrous sheath.

Calcium Binding tyrosine-(Y)-phosphorylation Regulated (CABYR) Antigen Profile

Protein Summary

To reach fertilization competence, spermatozoa undergo a series of morphological and molecular maturational processes, termed capacitation, involving protein tyrosine phosphorylation and increased intracellular calcium. The protein encoded by this gene localizes to the principal piece of the sperm flagellum in association with the fibrous sheath and exhibits calcium-binding when phosphorylated during capacitation. A pseudogene on chromosome 3 has been identified for this gene. Transcript variants of this gene encode multiple protein isoforms. An additional transcript and isoform has not been fully characterized.

Gene names and symbols associated with CABYR

  • calcium binding tyrosine phosphorylation regulated (Cabyr) antibody
  • calcium binding tyrosine phosphorylation regulated (CABYR) antibody
  • calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2) (Cabyr) antibody
  • 1700016C01Rik antibody
  • 4933421A18Rik antibody
  • CABYRa antibody
  • CABYRc antibody
  • CABYRc/d antibody
  • CABYRe antibody
  • CBP86 antibody
  • CT88 antibody
  • FSP-2 antibody
  • FSP2 antibody

Protein level used designations for CABYR

calcium-binding tyrosine-phosphorylation regulated protein , calcium binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2) , calcium-binding protein 86 , calcium-binding tyrosine phosphorylation-regulated protein , calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2) , cancer/testis antigen 88 , fibrousheathin 2 , fibrousheathin II , fibrousheathin-2 , testis-specific calcium-binding protein CBP86

GENE ID SPECIES
686189 Rattus norvegicus
26256 Homo sapiens
71132 Mus musculus
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