Calcium and Integrin-Binding Protein 1 (CIB1) ELISA Kits

CIB1 encodes a member of the EF-hand domain-containing calcium-binding superfamily. Additionally we are shipping CIB1 Antibodies (103) and CIB1 Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CIB1 10519 Q99828
CIB1 23991 Q9Z0F4
CIB1 81823 Q9R010
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Top CIB1 ELISA Kits at antibodies-online.com

Showing 5 out of 9 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human
  96 Tests 26 to 36 Days
$899.80
Details
Human
  96 Tests 31 to 41 Days
$728.20
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Mouse
  96 Tests 11 to 18 Days
$618.29
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Rat
  96 Tests 11 to 18 Days
$618.29
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Cow
  96 Tests 15 to 18 Days
$1,029.60
Details

More ELISA Kits for CIB1 Interaction Partners

Human Calcium and Integrin-Binding Protein 1 (CIB1) interaction partners

  1. Study in human dopaminergic neuroblastoma SH-SY5Y cells revealed that CIB1 physically associates with ASK1, and thereby prevents ASK1 activation induced by 1-methyl-4-phenylpyrinidium (MPP+). CIB1 binds to the region containing amino acid residues 378-648 of ASK1. CIB1 depletion by RNA interference potentiates MPP+-induced dopaminergic neuronal death.

  2. NBR1 interacts with fasciculation and elongation protein zeta-1 (FEZ1) and calcium and integrin binding protein (CIB) and shows developmentally restricted expression in the neural tube.

  3. CIB1 may regulate tumor biological processes that range from adhesion, migration, cell survival, proliferation, and angiogenesis [review]

  4. In patients with chronic stable ischemic heart failure, the diagnostic value of urine CIB1 outperforms that of serum pro-BNP

  5. this study identifies CIB1 and CIB2 as host helper factors for HIV-1 replication that are required for optimal receptor-mediated viral entry

  6. In summary, as a multifunctional protein, CIB1 serving not only as a Ca2+ modulating protein, most surprisingly, but also as an important potential tumor promoting factor. [review]

  7. Results suggest that interaction of CIB1 with alphaIIb is one of the early events occurring during outside-in signaling. Furthermore, CIB1 recruits FAK to the alphaIIbbeta3 complex at the filopodia where FAK is activated, which in turn activates c-Src, resulting in propagation of outside-in signaling leading to platelet spreading.

  8. we found that ectopic expression of oncogenic KRas and HRas in cells resulted in elevated CIB1 expression. We previously described the Ca(2+)-myristoyl switch function of CIB1, and its ability to facilitate agonist-induced plasma membrane localisation of sphingosine kinase 1 (SK1), a location where SK1 is known to elicit oncogenic signalling.

  9. a large subset of TNBCs depend on CIB1 for cell survival and tumor growth, independent of CIB1 expression levels.

  10. mRNA and protein expression levels of CIB1 were decreased in the oligoasthenozoospermia patients.CIB1 may be involved in the pathogenesis of oligoasthenozoospermia by the CDK1 signaling pathway.

  11. High serum CIB1 levels are associated with pancreatic cancer.s

  12. KIP binding to TRF2 enhances the telomere-binding activity of TRF2, suggesting that KIP acts as a positive regulator of TRF2 function.

  13. these studies suggested that Kaposi's sarcoma-associated herpesvirus utilizes CIB1 as one of the key molecule(s) to coordinate and sustain the EphA2 mediated signaling involved in its entry

  14. CIB1a is a novel mediator of PKD2-driven carcinogenesis.

  15. we present data that show that CIB1 binds to seven additional alpha-integrin CT peptides, bringing the total number of alpha-integrins that can associate with CIB1 to eight.

  16. Results indicate that CIB1 is uniquely positioned to regulate PI3K/AKT and MEK/ERK signaling and that simultaneous disruption of these pathways synergistically induces a nuclear GAPDH-dependent cell death.

  17. The CIB1 and calcineurin expression was increased in AF atrial tissue and was related to the type of AF. This finding suggests that CIB1 may be involved in the pathogenesis of AF in VHD patients.

  18. results suggest that CIB1 positively regulates cell migration and is necessary for the recruitment of FAK to the focal adhesions. Furthermore, CIB1-induced cell migration is dependent on MAP kinase signaling and its function is attenuated by PAK1

  19. CIB1 may be used as a novel prognostic factor and possibly an attractive therapeutic target for hepatocellular carcinoma.

  20. CaMy1 via SCG10 couples Ca(2+) signals with the dynamics of microtubules during neuronal outgrowth in the developing brain.

Mouse (Murine) Calcium and Integrin-Binding Protein 1 (CIB1) interaction partners

  1. Study shows that Cib1 negatively regulates degeneration of dopaminergic neurons in a mouse model of Parkinson's disease using 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Cib1 physically associated with apoptosis signal-regulating kinase 1 (Ask1) and thereby inhibited the 1-methyl-4-phenylpyrinidium-induced stimulation of the Ask1-mediated signaling cascade.

  2. mouse erythrocyte calmyrin is an interacting molecule of the rodent malaria parasite Plasmodium yoelii RhopH complex.

  3. results suggest that interaction of CIB1 with alphaIIb is one of the early events occurring during outside-in signaling. Furthermore, CIB1 recruits FAK to the alphaIIbbeta3 complex at the filopodia where FAK is activated, which in turn activates c-Src, resulting in propagation of outside-in signaling leading to platelet spreading.

  4. CIB1 is involved in regulating endomitosis, perhaps through its interaction with Polo-like kinase 3

  5. Data demonstrate that CIB1 is not required for AID to mediate antibody gene diversification processes. It remains possible that CIB1 has an alternative, a redundant or a subtle non-limiting regulatory role in AID biology.

  6. CIB1 functions as a previously undescribed regulator of cardiac hypertrophy through its ability to regulate the association of calcineurin with the sarcolemma and its activation.

  7. CIB1 is a key regulator of thrombosis, by affecting platelet spreading, but not platelet filopodia formation.

  8. CIB co-immunoprecipitated with Snk and inhibited the kinase activity of Snk, suggesting that CIB is a negative regulator for Snk kinase activity.

  9. MEFs derived from Cib1(-/-) mice exhibit a much slower growth rate compared to Cib1(+/+) MEFs, suggesting that CIB1 regulates the cell cycle, differentiation of spermatogenic germ cells, and/or differentiation of supporting Sertoli cells.

  10. loss of CIB1 in endothelial cells decreases p21-activated kinase 1 activation, downstream extracellular signal-regulated kinase 1/2 activation, and matrix metalloproteinase 2 expression, all of which are known to contribute to angiogenesis.

CIB1 Antigen Profile

Antigen Summary

This gene encodes a member of the EF-hand domain-containing calcium-binding superfamily. The encoded protein interacts with many other proteins, including the platelet integrin alpha-IIb-beta-3, DNA-dependent protein kinase, presenilin-2, focal adhesion kinase, p21 activated kinase, and protein kinase D. The encoded protein may be involved in cell survival and proliferation, and is associated with several disease states including cancer and Alzheimer's disease. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with CIB1

  • calcium and integrin binding 1 (calmyrin) (cib1) antibody
  • calcium and integrin-binding protein 1 (CpipJ_CPIJ003501) antibody
  • calcium and integrin binding 1 (CIB1) antibody
  • calcium and integrin binding 1 (cib1) antibody
  • Calcium and integrin-binding protein 1 (kip1) antibody
  • calcium and integrin binding 1 (calmyrin) (Cib1) antibody
  • calcium and integrin binding 1 (Cib1) antibody
  • Cib antibody
  • Cibkip antibody
  • CIBP antibody
  • Kip antibody
  • KIP1 antibody
  • Prkdcip antibody
  • Sip2-28 antibody
  • zgc:112015 antibody

Protein level used designations for CIB1

calcium and integrin-binding protein 1 , calcium and integrin binding protein 1 , Calcium and integrin-binding protein 1 , DNA-PK interaction protein , DNA-PKcs-interacting protein , DNA-dependent protein kinase interacting protein , SNK-interacting protein 2-28 , CIB , calcium and integrin binding, protein kinase interacting protein , calmyrin , kinase-interacting protein , protein kinase, DNA activated, catalytic polypeptide interacting protein , KIP , calcium- and integrin-binding protein

GENE ID SPECIES
550376 Danio rerio
6034872 Culex quinquefasciatus
100141300 Ovis aries
100286603 Salmo salar
100301714 Oncorhynchus mykiss
10519 Homo sapiens
23991 Mus musculus
81823 Rattus norvegicus
479044 Canis lupus familiaris
100157484 Sus scrofa
510141 Bos taurus
100726412 Cavia porcellus
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