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Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.. Additionally we are shipping CAPN1 Antibodies (127) and CAPN1 Proteins (6) and many more products for this protein.
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Authors provide the first evidence that calpain-1 regulates platelet hyperactivity in sickle mice.
A total of 55 genes were differentially expressed in micro-calpain knockout mice.
calpains inhibition plays crucial roles in vascular restenosis by preventing neointimal hyperplasia at the early stage via suppression of the MMP2 (show MMP2 ELISA Kits)/TGF-beta1 (show TGFB1 ELISA Kits) pathway.
indicate that calpain-1 and calpain-2 (show CAPN2 ELISA Kits) play opposite roles in high increased intraocular pressure-induced ischemic injury
Results strengthen the roles of both calpain-1 and PHLPP1 in synaptic plasticity and learning and memory, and illustrate the complexities of the interactions between multiple pathways participating in synaptic plasticity.
Genetic ablation of calpain-1 ameliorates chronic pain behavior in sickle cell mice.
Our results indicate that calpain mediates cytokine-induced collagen-I synthesis and proliferation of ASMCs via the mTORC2/Akt (show AKT1 ELISA Kits) signalling pathway, thereby regulating airway smooth muscle remodelling in asthma.
mutations in CAPN1 are an additional cause of ataxia in mammals, including humans.
Results indicate that calpain-1 and calpain-2 (show CAPN2 ELISA Kits) are differentially activated in hippocampus following seizure activity, with calpain-1 activation being limited to a small population of interneurons, and possibly triggering neuroprotective events, while calpain-2 (show CAPN2 ELISA Kits) is widely activated in pyramidal neurons of CA1 (show CA1 ELISA Kits) and CA3 (show CA3 ELISA Kits), and triggers neurodegenerative cascades.
Here we show the combined loss of glial glutamate (show GRIN1 ELISA Kits) transporters GLT1 (show SLC1A2 ELISA Kits) and GLAST (show SLC1A3 ELISA Kits) in spinal cord caused motor neuronal death and hindlimb paralysis.
Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
calpain 1, large subunit
, CANP 1
, calcium-activated neutral proteinase 1
, calpain mu-type
, calpain-1 catalytic subunit
, calpain-1 large subunit
, calpain 1