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postsynaptic membrane protein involved in excitatory synaptic transmission. Additionally we are shipping Calsyntenin 2 Antibodies (46) and and many more products for this protein.
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Study did not find support for an association of KIBRA either alone or in combination with CLSTN2 with memory performance or hippocampal volume, nor did variation in these genes influence longitudinal memory decline or hippocampal atrophy in older adults
The results of this study supports the view that effects of KIBRA and CLSTN2 polymorphisms genetic polymorphisms on cognitive functioning may be most easily disclosed at suboptimal levels of cognitive ability, such as in old-age depression.
No increased risk of any type of late development, and cognitive impairment was associated with CLSTN2 (rs6439886)
This study showed that the KIBRA and CLSTN2 genes interactively modulate episodic memory performance.
Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation [alcalpha1, alcbeta, alcgamma]
calsyntenins play an essential role in learning and this role is modulated both by CLSTN2 genotype and, during adolescent development, by exposure to tobacco smoke.
Study explored the in vivo effects of calsyntenin-2 deficiency on emotional and social behavioral endophenotypes in a mouse, found a striking effect of sex on expression of social behavior and emotionality in Clstn2-knock-out mice, but hyperactivity coupled with pronounced repetitive behavior was observed in Clstn2-knock-out mice of both sexes.
Results confirm a function for calsyntenin-2 in cognitive performance and indicate an underlying mechanism that involves parvalbumin interneurons and aberrant inhibitory transmission
postsynaptic membrane protein involved in excitatory synaptic transmission
, cadherin-related family member 13
, calsyntenin 2