Catenin, beta Interacting Protein 1 Proteins (CTNNBIP1)

The protein encoded by CTNNBIP1 binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. Additionally we are shipping CTNNBIP1 Antibodies (52) and CTNNBIP1 Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CTNNBIP1 67087 Q9JJN6
CTNNBIP1 56998 Q9NSA3
Rat CTNNBIP1 CTNNBIP1 503000  
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Top CTNNBIP1 Proteins at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,370.21
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,370.21
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 2 to 3 Days
$814.00
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 12 Days
$277.22
Details
Escherichia coli (E. coli) Human Un-conjugated SDS-PAGE analysis of Human CTNNbIP1 Protein. 100 μg Log in to see 11 to 18 Days
$596.97
Details
Escherichia coli (E. coli) Mouse Un-conjugated SDS-PAGE analysis of Mouse CTNNbIP1 Protein. 100 μg Log in to see 11 to 18 Days
$611.18
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,115.67
Details
Escherichia coli (E. coli) Human His tag   1 mg Log in to see 2 to 3 Days
$3,055.38
Details
Human Un-conjugated   1 mg Log in to see 6 Days
$3,435.54
Details

CTNNBIP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
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Human , ,
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More Proteins for Catenin, beta Interacting Protein 1 (CTNNBIP1) Interaction Partners

Mouse (Murine) Catenin, beta Interacting Protein 1 (CTNNBIP1) interaction partners

  1. miR-215-5p is a negative regulator of adipocyte differentiation through post-transcriptional regulation of FNDC3B and CTNNBIP1 during early adipogenesis

  2. miR-29b plays a pivotal role in fetal mouse neurogenesis by regulating ICAT-mediated Wnt/beta-catenin signaling.

  3. Mechanistic studies revealed that CTNNBIP1 suppresses Wnt/beta-catenin signaling and that miR-215 promotes beta-catenin activation and upregulates alpha-SMA and fibronectin expression in TGF-beta1-treated MMCs by targeting CTNNBIP1

  4. Overexpression of Icat induces G(2) arrest and cell death in tumor cell mutants for adenomatous polyposis coli, beta-catenin, or Axin.

  5. ICAT plays an important role in the anteriorization of neural cells by inhibiting the posteriorizing activity of Wnt signaling

  6. These results suggest that the loss of ICAT gene function causes the arrest of UB branching and the apoptotic death of MM cells, resulting in renal agenesis.

  7. Inhibition of beta-catenin signaling in articular chondrocytes causes increased cell apoptosis and articular cartilage destruction in Col2a1-ICAT- transgenic mice.

Human Catenin, beta Interacting Protein 1 (CTNNBIP1) interaction partners

  1. Data demonstrated that ICAT was highly expressed in cervical cancer tissues and had a role in control of epithelial-mesenchymal transition (EMT) in cervical cancer cells. Its overexpression promoted cell proliferation, migration, invasion and resulted in EMT by disrupting the stability of E-cadherin/betacatenin complex.

  2. Low PLD1 expression and high ICAT expression were significantly associated with increased survival in colorectal cancer patients.

  3. The present work aims to investigate the relationship between the expression of AEG-1(astrocyte elevated gene-1), b-FGF(basic-fibroblast growth factor), beta-catenin, Ki-67, TNF-alpha (tumor necrosis factor-alfa) other prognostic parameters in DC (Ductal Carcinomas) and ductal intraepithelial neoplasm. We found a relationship between these factors.

  4. Overexpression of ICAT promoted Caski cells' proliferation, arrested the cell cycle in the S phase and enhanced cell migration. Conclusion Overexpression of ICAT can promote the proliferation and migration of Caski cervical cancer cells.

  5. Somatic mutation of beta-catenin (CTNNB1) is known to be crucial for Wilms tumor development in up to 15% of cases.

  6. CTNNBIP1 expression correlated with longer overall survival in LAC patients. This study reveals that miR-214 plays a critical role in CSLC self-renewal and stemness by targeting CTNNBIP1.

  7. Data show that microRNA miR-215 activates beta-catenin pathways by decreasing catenin beta interacting protein 1 (CTNNBIP1)expression in gliomas.

  8. Simultaneous silencing of beta-catenin and STAT3 synergistically induces apoptosis and inhibits cell proliferation in HepG2 liver cancer cells.

  9. Finally, pro-incubation with idebenone inhibited mitochondrial dysfunction induced by oxLDL through the mitochondrial-dependent apoptotic pathway and GSK3beta/beta-catenin signalling pathways.

  10. A potent beta-catenin inhibitor, ICAT/CTNNBIP1 was a direct target of miR-424-5p.

  11. Particulate matter (PM10) downregulates E-Cadherin/beta-Catenin expression.

  12. A statistically significant lapatinib- and gefitinib-induced repression of cyclin D1, MMP9 and beta-catenin in CERV196 cells.

  13. Nuclear YAP and cytoplasmic beta-catenin play important roles in carcinogenesis.

  14. review of control of cell fate and proliferation in colon cancer

  15. miR-603 regulates glioma development via Wnt-beta-cateninn signaling pathway and its WIF1 and CTNNBIP1 targets.

  16. These results indicate that beta-catenin translation is initiated via the IRES and this is regulated by PTX, suggesting that regulation of the IRES-dependent translation of beta-catenin may be involved in the cancer cell response to PTX treatment.

  17. ICAT may serve as a tumor-suppressor in human glioma.

  18. Suppressing TrpC5 expression decreased nuclear beta-catenin accumulation, reduced the induction of ABCB1, and reversed 5-fluorouracil neoplastic resistance.

  19. Our results indicate that HDAC1 plays an important role in chondrogenesis and may represent a therapeutic target for modulation of cartilage development.

  20. ASPP2 prevents beta-catenin from transactivating ZEB1 directly by forming an ASPP2-beta-catenin-E-cadherin ternary complex

CTNNBIP1 Protein Profile

Protein Summary

The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with CTNNBIP1

  • catenin, beta interacting protein 1 (ctnnbip1)
  • catenin beta interacting protein 1 L homeolog (ctnnbip1.L)
  • catenin beta interacting protein 1 S homeolog (ctnnbip1.S)
  • catenin beta interacting protein 1 (ctnnbip1)
  • catenin, beta interacting protein 1 (CTNNBIP1)
  • catenin beta interacting protein 1 (CTNNBIP1)
  • catenin beta interacting protein 1 (Ctnnbip1)
  • catenin, beta-interacting protein 1 (Ctnnbip1)
  • 1110008O09Rik protein
  • 2310001I19Rik protein
  • AW457332 protein
  • catnbip1 protein
  • CTNNBIP1 protein
  • ctnnbip1a protein
  • ctnnbip1b protein
  • fa95e12 protein
  • Icat protein
  • wu:fa95e12 protein

Protein level used designations for CTNNBIP1

beta-catenin-interacting protein , beta-catenin-interacting protein 1 , catenin, beta interacting protein 1 a , catenin beta interacting protein 1 b , catenin, beta interacting protein 1 , inhibitor of beta-catenin and Tcf-4 , beta-catenin-interacting protein ICAT

GENE ID SPECIES
58117 Danio rerio
399114 Xenopus laevis
446455 Xenopus laevis
493465 Xenopus (Silurana) tropicalis
608589 Canis lupus familiaris
712257 Macaca mulatta
749394 Pan troglodytes
67087 Mus musculus
56998 Homo sapiens
771460 Gallus gallus
614630 Bos taurus
503000 Rattus norvegicus
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