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May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1) (By similarity).. Additionally we are shipping CTNNAL1 Proteins (5) and many more products for this protein.
Showing 10 out of 31 products:
Human Polyclonal CTNNAL1 Primary Antibody for WB - ABIN522176
Fan, Chiang, Liang, Tsai, Wong, Chen, Hong, Chen: ?-Catulin knockdown induces senescence in cancer cells. in Oncogene 2011
Force-dependent conformational switch of alpha-catenin controls vinculin binding.
Alpha-catenin has a novel role in fine-tuning of tissues' viscosity and surface tension through contractility.
the interaction between alpha-catulin and alpha-dystrobrevin is evolutionarily conserved in C. elegans and mouse muscles and strongly suggests that this interaction contributes to the integrity of the dystrophin complex
We observed the temporal and spatial distribution of CTNNAL1 expression in mouse lung tissue with the OVA-sensitized asthma model and found that the level of CTNNAL1 mRNA showed a prominent negative correlation with pulmonary resistance.
This study identifies the E-cadherin/catenin complex as a discriminative, partly polyamine-regulated feature of IL-4/IL-13-exposed alternatively activated macrophages
These data indicated that upregulated expression of alpha-catulin protein might have impact on the tumorigenesis of head and neck squamous cell carcinoma
Alpha-catulin contributes to drug-resistance of melanoma by activating NF-kappaB and AP-1
these results strongly indicate that alpha-catulin contributes to the invasive behavior of metastatic cells and may be used as a prognostic marker and future therapeutic target for patients with cancer.
our study shows that alpha-catulin plays a critical role in cancer metastasis
findings show that alpha-catulin is highly expressed in melanoma cells; expression of alpha-catulin promoted melanoma progression and occurred concomitantly with the downregulation of E-cadherin and the upregulation of expression of mesenchymal genes
a robust transcriptional CTNNAL1 up-regulation occurs during acute ozone-induced stress and is mediated at least in part by ozone-induced recruitments of LEF-1 and AP-2alpha to the human CTNNAL1 promoter
Study provides evidence that alpha-catulin promotes tumor growth by preventing cellular senescence and suggests that downregulating alpha-catulin may be a promising therapeutic approach for cancer treatment.
Data show that alpha-dystrobrevin-1 recruits alpha-catulin, which supersensitizes alpha(1D)-AR functional responses by recruiting effector molecules to the signalosome.
the Lbc/alpha-catulin axis participates in 5-HT-induced PASMC mitogenesis and RhoA/ROCK signaling, and may be an interventional target in diseases involving vascular smooth muscle remodeling.
alpha-catulin maps precisely to the familial dysautonomia candidate region on 9q31.
Results show that alpha-catulin co-expression leads to increased Lbc-induced serum response factor activation and may modulate Rho pathway signaling in vivo by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor.
Abnormal expression of alpha-catenin was seen in mucoepidermoid carcinoma.
alpha-catenin and alpha-catulin have distinct activities that downregulate, respectively, beta-catenin and Ras signals converging on the cyclin D1 promoter
CTNNAL1 mRNA expression is highly correlated to airway resistance; CTNNAL1 may contribute to the wound repair and proliferation of HBEC. Furthermore, it may serve to Fn mediated cell-extracellular adhesion and its signal transduction.
Alpha-catulin has tumorigenic potential.
Seven placental transcripts characterize HELLP-syndrome.
May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1) (By similarity).
, catenin alpha-like 1
, catenin (cadherin-associated protein), alpha-like 1
, alpha-catenin related protein
, alpha-catenin-related protein
, catenin alpha-like protein 1