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The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. Additionally we are shipping CENPM Kits (13) and CENPM Proteins (10) and many more products for this protein.
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CENP-M is crucially required for the assembly and stability of a tetramer also comprising CENP-I (show CENPI Antibodies), CENP-H (show CENPH Antibodies), and CENP-K (show CENPK Antibodies), the HIKM complex, which we extensively characterize through a combination of structural, biochemical, and cell biological approaches.
Expression of the human PANE1 gene was detected preferentially in immune cells
an alternative transcript of the proliferation-associated nuclear element 1 (PANE1) gene encodes a novel (HLA)-A(*)0301-restricted mHAg (show MYO1G Antibodies) that is selectively expressed in B-lymphoid cells
PANE1 localizes to the centromere throughout the cell cycle and its localization is dependent on the centromere specific histone (show CENPA Antibodies) variant CENP-A (show CENPA Antibodies).
A new 20 kDa protein (PANE1) induced upon transdifferentiation was nuclear in nonconfluent cells and cytoplasmic in confluent or dividing cells.
cloning and characterization of the cDNA sequence of porcine PANE1, which shares high sequence identity with their mammalian counterparts
The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPM is an additional factor required for centromere assembly (Foltz et al., 2006
interphase centromere complex protein 39
, proliferation associated nuclear element 1
, proliferation-associated nuclear element protein 1
, centromere protein M
, Centromere protein M