Ceramide Synthase 1 Proteins (CERS1)

CERS1 encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. Additionally we are shipping Ceramide Synthase 1 Antibodies (40) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CERS1 10715 P27544
CERS1 93898 P27545
Rat CERS1 CERS1 290658  
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Top Ceramide Synthase 1 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days

CERS1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
Mouse (Murine)

More Proteins for Ceramide Synthase 1 (CERS1) Interaction Partners

Human Ceramide Synthase 1 (CERS1) interaction partners

  1. Single nucleotide polymorphisms in the gene LASS1 associated with programmed cell death, providing a potential cellular mechanism for the effects on tissue damage and circulating Creatine kinase.

  2. This study highlights a close interaction between CLN5 (show CLN5 Proteins)/CLN8 proteins, and their role in sphingolipid metabolism. Our findings suggest that CLN5p/CLN8p most likely are positive modulators of CerS1 and/or CerS2 (show CERS2 Proteins).

  3. Moreover, an alternatively spliced variant CerS1 mRNA (CerS1-2) was detected mainly in cancer cells or primary tumour tissues compared to controls, which was targeted by miR (show MLXIP Proteins)-574-5p for degradation

  4. The variation in LASS1 is functional, causing enhanced expression of the gene, and it contributes to healthy aging and greater survival in the tenth decade of life.

  5. The study suggests that diverse stresses initiate responses through different signaling pathways, which ultimately converge to regulate CerS1 localization.

  6. regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cel

  7. LAG1 (show CCL4 Proteins) and C18 (show BBS9 Proteins)-ceramide have roles in the regulation of growth of HNSCC

Mouse (Murine) Ceramide Synthase 1 (CERS1) interaction partners

  1. The strong association of LCB (show CLTB Proteins) levels with neuronal survival both in vivo and in vitro suggests high-level accumulation of LCBs is a possible underlying cause of the CerS1 deficiency-induced neuronal death.

  2. CerS1, -2, and -6 are hyperacetylated in the mitochondria of SIRT3 (show SIRT3 Proteins)-null mice.

  3. Data indicate that oxidized phospholipids (OxPLs)-induced ceramide synthases (CerS1-Cers6 (show CERS6 Proteins)) activity in macrophages is responsible for the accumulation of ceramide.

  4. an essential function of CerS1-derived ceramide in the regulation of cerebellar development and neurodevelopmentally regulated behavior.

Arabidopsis thaliana Ceramide Synthase 1 (CERS1) interaction partners

  1. Findings indicate that AtORM1 and AtORM2 mediation of serine palmitoyltransferase (SPT) activity differentially regulates functionally distinct ceramide synthase activities as part of a broader sphingolipid homeostatic regulatory network.

Ceramide Synthase 1 (CERS1) Protein Profile

Protein Summary

This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. Members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in yeast suggest that the encoded protein is involved in aging. This protein is transcribed from a monocistronic mRNA as well as a bicistronic mRNA, which also encodes growth differentiation factor 1.

Gene names and symbols associated with Ceramide Synthase 1 Proteins (CERS1)

  • ceramide synthase 1 (CERS1)
  • ceramide synthase 1 (Cers1)
  • TRAM, LAG1 and CLN8 (TLC) lipid-sensing domain containing protein (LAG1)
  • LAG1 protein
  • LAG1 HOMOLOG 1 protein
  • Lass1 protein
  • to protein
  • Uog-1 protein
  • UOG1 protein

Protein level used designations for Ceramide Synthase 1 Proteins (CERS1)

longevity assurance gene 1 , longevity assurance (LAG1, S. cerevisiae) homolog 1 , longevity assurance gene 1 protein homolog 1 , protein UOG-1 , upstream of GDF1 , LAG1 homolog, ceramide synthase 1 , LAG1 longevity assurance homolog 1 , longevity assurance homolog 1 , longevity assurance-like protein 1

468773 Pan troglodytes
10715 Homo sapiens
615296 Bos taurus
93898 Mus musculus
290658 Rattus norvegicus
609789 Canis lupus familiaris
100525450 Sus scrofa
822140 Arabidopsis thaliana
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