Chemokine (C-C Motif) Receptor 4 (CCR4) ELISA Kits

The protein encoded by CCR4 belongs to the G-protein-coupled receptor family .

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human CCR4 CCR4 1233 P51679
Anti-Mouse CCR4 CCR4 12773 P51680
Anti-Rat CCR4 CCR4 171054  
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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.058 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
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More ELISA Kits for CCR4 Interaction Partners

Human Chemokine (C-C Motif) Receptor 4 (CCR4) interaction partners

  1. the expression of chemokine (show CCL1 ELISA Kits) receptors in different peripheral blood T-cell subsets in patients with polymyositis (PM) and dermatomyositis, was examined.

  2. This review presents key clinical studies of Multiple sclerosis together with experimental studies in animals that have demonstrated functional roles of CCR4, CCL17 (show CCL17 ELISA Kits), and CCL22 (show CCL22 ELISA Kits) in experimental autoimmune encephalomyelitis pathogenesis. [review]

  3. Taken together, our data showed a likely positive feedback mechanism of enhanced IL-6 (show IL6 ELISA Kits) production in ectopic milieu. The high levels of IL-6 (show IL6 ELISA Kits) in the peritoneal cavity stimulate the expression of CCL17 (show CCL17 ELISA Kits) in endometrial stromal cells by activating JNK (show MAPK8 ELISA Kits) signal pathway, and then, CCL17 (show CCL17 ELISA Kits) further induces CCR4 expression on macrophages, which eventually leads to an increase in IL-6 (show IL6 ELISA Kits) production via NF-kappaB (show NFKB1 ELISA Kits) activation.

  4. Investigations showed that the level of CCR4 could be induced by TNF-alpha (show TNF ELISA Kits) dependent of NF-kappaB (show NFKB1 ELISA Kits) activation in CRC (show CALR ELISA Kits) cells. CCR4 might be implicated in TNF-alpha (show TNF ELISA Kits)-regulated cancer cells metastasis.

  5. Tumor-associated macrophages promote prostate cancer migration through activation of the CCL22 (show CCL22 ELISA Kits)-CCR4 signaling axis.

  6. monocyte chemoattractant protein-1 (MCP-1 (show CCL2 ELISA Kits)), an endogenous CCR4-binding ligand, was specifically upregulated in the head and neck squamous cell carcinomamicroenvironment compared to the other four CCR4-binding ligands

  7. Chemokine (show CCL1 ELISA Kits) receptors CCR3 (show CCR3 ELISA Kits) and CCR4, and the mucosa specific chemokine (show CCL1 ELISA Kits) CCL28 (show ENC1 ELISA Kits) have predominant roles in oral wound healing by increasing human gingiva fibroblast proliferation, migration, and the secretion of IL-6 (show IL6 ELISA Kits) and HGF (show HGF ELISA Kits) and reducing the secretion of TIMP-1 (show TIMP1 ELISA Kits).

  8. A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer

  9. The percentage of CXCR3 (show CXCR3 ELISA Kits)(+) CD4 (show CD4 ELISA Kits)(+) TEM (show CYLD ELISA Kits) cells negatively correlated with the severity of the cutaneous disease in psoriasis patients. Importantly CLA (show SELPLG ELISA Kits)(+) CD4 (show CD4 ELISA Kits)(+) TCM cells expressing CCR6 (show CCR6 ELISA Kits)(+) or CCR4(+)CXCR3 (show CXCR3 ELISA Kits)(+) negatively correlated with psoriasis severity suggesting recruitment to the skin compartment.

  10. Case Report: CCR4+ T-cell depletion by mogamulizumab treatment of adult T-cell leukaemia/lymphoma results in CD8 (show CD8A ELISA Kits)-positive T-cell mediated dermatitis.

Mouse (Murine) Chemokine (C-C Motif) Receptor 4 (CCR4) interaction partners

  1. data demonstrate a mechanistic or developmental role of CCR4 in the regulation of locomotor and exploratory behaviors

  2. A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer

  3. CCR4 is critically involved in regional lymph node dendritic cell-Th17 cell interactions that are necessary for Th17 cell-mediated induction of antitumor CD8 (show CD8A ELISA Kits)+ effector T cells in mice bearing B16 melanoma.

  4. CCR4 is involved in immunosuppression after severe sepsis and suggest that CCR4+ Regulatory T Cells negatively modulate the short and long-term immune responses.

  5. CCL22 (show CCL22 ELISA Kits) was localised mainly on the cell surface and or in the cytoplasm. Within sections of omental milky spot micrometastases, CCR4 was recognised on or in gastric cancer cells, constituent cells milky spots, blood cells and blood endothelial cells

  6. CCR4 is involved in regulating negative selection of polyclonal and T cell receptor (TCR) transgenic thymocytes

  7. results show that the IL-4 (show IL4 ELISA Kits)/CCL22 (show CCL22 ELISA Kits)/CCR4 axis is involved in the migration of Tregs to osteolytic lesion sites, and attenuates development of lesions by inhibiting inflammatory migration and the production of proinflammatory and osteoclastogenic mediators

  8. These data have uncovered a novel role of core components of the Ccr4-Not complex as regulators of transition from partial to genuine induced pluripotent stem cells.

  9. that effective engagement of CCR4 by CCL17 (show CCL17 ELISA Kits) involves two distinct binding domains and interaction with both is required for signaling

  10. NF-kappaB (show NFKB1 ELISA Kits) signaling pathway was involved in the asthmatic change induced by CKLF1, among which CCR4 might play a crucial role

CCR4 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.

Gene names and symbols associated with CCR4

  • C-C motif chemokine receptor 4 (CCR4) antibody
  • C-C motif chemokine receptor 4 (Ccr4) antibody
  • chemokine (C-C motif) receptor 4 (Ccr4) antibody
  • C-C CKR-4 antibody
  • CC-CKR-4 antibody
  • Ccr4 antibody
  • CD194 antibody
  • CHEMR1 antibody
  • ChemR13 antibody
  • CKR4 antibody
  • Cmkbr4 antibody
  • HGCN:14099 antibody
  • K5-5 antibody
  • LESTR antibody
  • Sdf1r antibody

Protein level used designations for CCR4

C-C CKR-4 , C-C chemokine receptor type 4 , CCR-4 , chemokine (C-C) receptor 4 , chemokine (C-C motif) receptor 4 , C-C chemokine receptor type 4-like , c-C chemokine receptor type 4-like , nocturnin , CC-chemokine receptor 4 , fusin , leukocyte-expressed seven-transmembrane-domain receptor , CC chemokine receptor 4 , CC-CKR-4 , C-C chemokine receptor 4

1233 Homo sapiens
100397096 Callithrix jacchus
100445664 Pongo abelii
100585668 Nomascus leucogenys
100379615 Cavia porcellus
12773 Mus musculus
403541 Canis lupus familiaris
408019 Bos taurus
171054 Rattus norvegicus
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