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B lymphocyte chemoattractant, independently cloned and named Angie, is a CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. Additionally we are shipping CXCL13 Antibodies (158) and CXCL13 Kits (41) and many more products for this protein.
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Human CXCL13 Protein expressed in Wheat germ - ABIN1350816
Nikolakopoulou, Dutta, Chen, Miller, Trapp: Activated microglia enhance neurogenesis via trypsinogen secretion. in Proceedings of the National Academy of Sciences of the United States of America 2013
This study indicated that CXCL13 may be pathogenically involved in Clostridium difficile infection (CDI) and served as a potential new biomarker for diagnosis and prognosis in CDI.
CXCL13 has a role in directing B-lymphocyte (show AKAP17A Proteins) migration
CXCL13 and CXCR5 (show CXCR5 Proteins) contribute to orofacial pain via ERK (show EPHB2 Proteins)-mediated proinflammatory cytokines production.
High glucose could inhibit osteogenic differentiation of mesenchymal stem cells by lncRNA AK028326 mediated down-regulation of CXCL13 expression.
Data demonstrate that CXCL13 is not essential in mounting effective peripheral humoral responses, but specifically promotes CNS accumulation of differentiated B cells.
overexpression of CXCL13 is associated with myasthenia gravis.
Deficiency in Cxcl13 or its receptor, Cxcr5 (show CXCR5 Proteins), significantly attenuated benzo(a)pyrene-induced lung cancer in mice, demonstrating CXCL13's critical role in polycyclic aromatic hydrocarbon-induced lung carcinogenesis.
Blockade of CXCL13 significantly reduced urine protein, serum creatinine, and dramatically attenuated renal pathology injury in lupus nephritis in mice.
Results from this study suggest blockade of CXCL13 and BAFFR (show TNFRSF13C Proteins) together may be an effective therapeutic strategy in preventing salivary hypofunction and reducing autoantibody titers and sialadenitis in patients with Sjogren's syndrome
findings reveal a neuronal/astrocytic interaction in the spinal cord by which neuronally produced CXCL13 activates astrocytes via CXCR5 (show CXCR5 Proteins) to facilitate neuropathic pain.
Studied CSF (show CSF2 Proteins) levels of B-lymphocyte Chemoattractant CXCL13 in children with Lyme neuroborreliosis (LNB), and found CSF (show CSF2 Proteins) CXCL13 levels were substantially higher in children with LNB compared with children with other diagnoses.
This study indicated that CXCL13 rather than IL-31 (show IL31 Proteins) may have clinical values of diagnosis and prognosis in hepatocellular carcinoma.
CXCL13/CXCR5 (show CXCR5 Proteins) mediated the aggregation of B cells, that directed the aberrant humoral immune responses via the formation of ectopic germinal centers, which suggests a molecular mechanism of neurological damage in neurosyphilis.
High CXCL13 expression is associated with B-cell Lymphoma.
CCL21 (show CCL21 Proteins) and CXCL13 levels are increased in the minor salivary glands of patients with Sjogren's syndrome.
we demonstrate that PKCepsilon (show PRKCE Proteins) cooperates with the loss of the tumor suppressor Pten for the development of prostate cancer in a mouse model. Mechanistic analysis revealed that PKCe (show PRKCE Proteins) overexpression and Pten loss individually and synergistically upregulate the production of the chemokine (show CCL1 Proteins) CXCL13, which involves the transcriptional activation of the CXCL13 gene
During remission, serum CXCL13 and BAFF (show TNFSF13B Proteins) levels have not decreased to normal in neuromyelitis optica patients, and B-cell-related autoimmune response persists. Immunosuppressive therapy decreased serum BAFF (show TNFSF13B Proteins) levels, but did not affect CXCL13 expression.
This study suggested that increased serum levels of CXCL13 might be involved in renal ectopic lymphoid tissue (ELT)formation and renal impairment process in lupus nephritis.
CXCL13 mRNA expression and protein levels were significantly up-regulated in the brain from temporal lobe epilepsy patients.
B lymphocyte chemoattractant, independently cloned and named Angie, is a CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles.
C-X-C motif chemokine 13
, B lymphocyte chemoattractant
, CXC chemokine BLC
, small inducible cytokine subfamily B (Cys-X-Cys), member 13
, small-inducible cytokine B13
, B-cell chemoattractant
, B-cell-attracting chemokine 1
, B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1)
, B-lymphocyte chemoattractant
, b cell-attracting chemokine 1
, b lymphocyte chemoattractant
, chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant)
, small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cell chemoattractant)