Chibby Homolog 1 (Drosophila) Proteins (CBY1)

Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. Additionally we are shipping CBY1 Antibodies (34) and CBY1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CBY1 25776 Q9Y3M2
CBY1 73739 Q9D1C2
CBY1 246768 Q8K4I6
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Top CBY1 Proteins at antibodies-online.com

Showing 8 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,258.67
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,258.67
Details
Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Log in to see 15 to 18 Days
$576.00
Details
Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 15 to 18 Days
$608.00
Details

CBY1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , ,
Mouse (Murine)

Rat (Rattus)

More Proteins for Chibby Homolog 1 (Drosophila) (CBY1) Interaction Partners

Xenopus laevis Chibby Homolog 1 (Drosophila) (CBY1) interaction partners

  1. Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression.

Human Chibby Homolog 1 (Drosophila) (CBY1) interaction partners

  1. FAM92 proteins interact with Cby1 to promote ciliogenesis via regulation of membrane-remodeling processes.

  2. chronic Cby1 knockdown in colon cancer cells may counteract tumor progression by promoting the mesenchymal-to-epithelial transition process.

  3. Cby's C-terminal domain alone binds to TC-1 with significantly greater affinity compared to full-length Cby, implying that target binding of the coiled-coil domain is affected by the flanking disordered regions.

  4. CBY1 downregulation in CML (show BCR Proteins) comes from reduced protein stability when bound to 14-3-3sigma adapter protein (show TOLLIP Proteins). Dissociation raises CBY1 protein levels by enhancing its stability. The ubiquitin proteasome system reduces 14-3-3sigma-bound CBY1 stability by SUMOylation.

  5. Results show the hypermethylation of CBY1 and BCL2 (show BCL2 Proteins)-like11 promoters proceeding from DNMT1 (show DNMT1 Proteins) is a crucial component of their reduced expression, but it is not directly involved in chronic myeloid leukemia (show BCL11A Proteins) resistance to imatinib.

  6. Study showed that expression of Cby protein was strongly downregulated in laryngeal squamous cell carcinoma (LSCC) tumor tissues in comparison to normal laryngeal mucosa samples.

  7. the impact of BCR (show BCR Proteins)-ABL1 (show ABL1 Proteins) on Chibby1, a beta (show SUCLA2 Proteins) catenin (show CTNNB1 Proteins) antagonist involved in cell differentiation and transformation

  8. Stable expression of CBY1 drives beta catenin (show CTNNB1 Proteins) cytoplasmatic translocation and impairs beta catenin (show CTNNB1 Proteins) signaling in BCR-ABL (show ABL1 Proteins) + cells.

  9. Results from the association analysis suggest that common variation in CBY is not a cause for obesity in the Belgian population.

  10. C-terminal polycystin-2 (show PKD2 Proteins) influences the interaction with PIGEA14

Mouse (Murine) Chibby Homolog 1 (Drosophila) (CBY1) interaction partners

  1. FAM92 proteins interact with Cby1 to promote ciliogenesis via regulation of membrane-remodeling processes.

  2. Cby1 is required for efficient recruitment of Ahi1 (show AHI1 Proteins), providing a possible molecular mechanism for the ciliogenesis defect in Cby1(-/-) cells.

CBY1 Protein Profile

Protein Summary

Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CBY1

  • chibby homolog 1 S homeolog (cby1.S)
  • chibby homolog 1 (cby1)
  • chibby family member 1, beta catenin antagonist (CBY1)
  • chibby family member 1, beta catenin antagonist (Cby1)
  • 1110014P06Rik protein
  • arb1 protein
  • C22orf2 protein
  • CBY protein
  • chibby protein
  • HS508I15A protein
  • Pgea1 protein
  • PGEA14 protein
  • PIGEA-14 protein
  • PIGEA14 protein

Protein level used designations for CBY1

chibby homolog 1 , leucine-rich protein , ARPP-binding protein , PKD2 interactor, Golgi and endoplasmic reticulum-associated 1 , PKD2 interactor, golgi and endoplasmic reticulum associated 1 , coiled-coil protein PIGEA-14 , cytosolic leucine-rich protein , polycystin-2 interactor, Golgi- and endoplasmic reticulum-associated protein, 14 kDa , protein chibby homolog 1 , PIGEA-14

GENE ID SPECIES
398327 Xenopus laevis
549007 Xenopus (Silurana) tropicalis
25776 Homo sapiens
73739 Mus musculus
246768 Rattus norvegicus
282859 Bos taurus
Selected quality suppliers for CBY1 Proteins (CBY1)
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