anti-Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) Antibodies

Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. Additionally we are shipping Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Kits (71) and Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Proteins (24) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CHI3L1 12654 Q61362
CHI3L1 1116 P36222
CHI3L1 89824 Q9WTV1
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Top anti-Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Antibodies at antibodies-online.com

Showing 10 out of 105 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IF, WB <b>WB Suggested Anti-CHI3L1 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of YKL-40 expression in HEK293T (A), Raw264.7 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Mouse Un-conjugated ELISA, WB Chitinase 3-like 1 Antibody (2C10) [NBP1-28610] - SW480 cell lysate (40ug) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CHI3L1 (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Western Blot: Chitinase 3-like 1 Antibody (2C10) [NBP1-28610] - Cell lysates of HepG2 (35ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human CHI3L1 (1:250). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. 0.1 mL Log in to see 7 to 9 Days
$447.56
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 7 to 9 Days
$676.50
Details
Mouse Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated FACS, IF (p), IHC (p) HepG2 cells probed with Rabbit Anti-CHI3L1 Polyclonal Antibody  Alexa Fluor 488 Secondary 100 μL Log in to see 14 to 21 Days
$295.90
Details
Human Rabbit FITC ICC, IF, IHC, WB 100 μg Log in to see 13 to 16 Days
$398.00
Details
Human Rabbit Un-conjugated ICC, IHC, IP, WB 100 μg Log in to see 13 to 16 Days
$332.00
Details
Mouse Rabbit Un-conjugated ICC, IHC, IP, WB 100 μg Log in to see 13 to 16 Days
$342.00
Details

CHI3L1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


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Rat (Rattus)


Top referenced anti-Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Antibodies

  1. Human Monoclonal CHI3L1 Primary Antibody for ELISA - ABIN2472953 : Iwarson: [The pattern of non-A, non-B hepatitis is more and more evident. A new test for diagnosis of hepatitis C makes it possible to mass screen blood donors]. in Läkartidningen 1990 (PubMed)
    Show all 4 Pubmed References

  2. Cow (Bovine) Polyclonal CHI3L1 Primary Antibody for IF, WB - ABIN2784693 : Ober, Tan, Sun, Possick, Pan, Nicolae, Radford, Parry, Heinzmann, Deichmann, Lester, Gern, Lemanske, Nicolae, Elias, Chupp: Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function. in The New England journal of medicine 2008 (PubMed)
    Show all 2 Pubmed References

More Antibodies against Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Interaction Partners

Mouse (Murine) Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) interaction partners

  1. CHI3L1-mediated cell proliferation/survival involves partial downregulation of the pro-apoptotic S100A9 (show S100A9 Antibodies) protein that is highly expressed during the acute phase of colitis, by binding to the S100A9 (show S100A9 Antibodies) receptor, RAGE (show AGER Antibodies) (Receptor for Advanced Glycation End products).

  2. IL-18 (show IL18 Antibodies) is a potent stimulator of Chi3l1 and that Chi3l1 is an important mediator of IL-18 (show IL18 Antibodies)-induced inflammatory, fibrotic, alveolar remodeling, and cytotoxic responses.

  3. CHI3L1 is induced during fungal infection, and it regulated antifungal innate immune responses in the cornea.

  4. Astrocytic expression of chitinase 3-like protein 1 limits the extent of both astrocytic and microglial/macrophage facets of neuroinflammation.

  5. Results do not support a role of BRP (show GDF5 Antibodies)-39 in the pathogenesis of experimental autoimmune encephalitis.

  6. CHI3L1 was increased in plasma and brain tissue in experimental cerebral malaria, but targeted Chi3l1 deletion did not alter cytokine production or survival in this model.

  7. mechanism of BRP (show GDF5 Antibodies)-39 in bleomycin-induced pulmonary fibrosis

  8. Sem7a and its receptors regulate Chi3l1 in pulmonary melanoma metastasis

  9. Data show that IL-1 (show IL1A Antibodies)-induced transcriptin factor RelB (show RELB Antibodies)/NF-kappa B p50 (show NFKB1 Antibodies) Subunit complex formation was further promoted by oncostatin M (show OSM Antibodies) and that these complexes directly bound to the secreted protein cartilage glycoprotein 39 (YKL-40) promoter.

  10. These results indicate that catalytically inactive BRP (show GDF5 Antibodies)-39 and Ym1 (show CHI3L3 Antibodies) are constitutive genes in normal mouse lung.

Human Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) interaction partners

  1. Besides being associated with tau pathology, CSF (show CSF2 Antibodies) YKL-40 adds to the growing array of biomarkers reflecting distinct molecular brain mechanisms potentially useful for stratifying individuals for biomarker-guided, targeted anti-inflammatory therapies emerging from precision medicine.

  2. SNPs in CHI3L1 and cord blood YKL-40 were not associated with lung function measurements at 5 weeks and 6 years, respiratory symptoms in the first year, and allergic sensitisation at 6 years. Genetic variation in CHI3L1 might be related to the development of milder forms of asthma.

  3. Increased serum YKL-40 was related with poor collateral development and high SYNTAX score in patients with coronary artery disease.

  4. Plasma YKL-40 and IL-6 (show IL6 Antibodies) had less diagnostic impact than CA 19.9

  5. Findings show high level of both YKL-40 and GAP-43 (show GAP43 Antibodies) in CSF (show CSF2 Antibodies) of older women with suicidal ideation which suggest that a disrupted synaptic glial functioning and inflammation may be related to the aetiology of suicidal ideation in older adults.

  6. fibroblast-derived Chi3L1 as a novel key player in the complex reciprocal interactions of stromal cells that facilitate tumor progression and metastasis.

  7. Findings suggest that elevated serum YKL-40 levels are associated with the existence of uterine leiomyomas, and YKL-40 might be a potential adjunct biomarker for diagnosis of uterine leiomyomas.

  8. Collagen binds in two locations at the YKL-40 surface, potentially related to a role in fibrillar formation. Finally, heparin non-specifically binds at the YKL-40 surface, as predicted from structural studies

  9. This is the first report on the association between low-frequency and common variants in the chitinases-related genes CHIA and CHI3L1 with the intensity of specific IgE to ABA-1 in a population naturally exposed to Ascaris and with Bet v 1 in a Swedish population.

  10. results indicate that patients with CHI3L1 rs880633 variant genotypes TC+CC are at a higher risk of HCC (show FAM126A Antibodies). CHI3L1 polymorphisms rs880633 or rs4950928 may be potential candidates for predicting poor HCC (show FAM126A Antibodies) prognosis and clinical status.

Cow (Bovine) Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) interaction partners

  1. chitinase-like lectin, YKL-40, binds specifically to type I collagen and modulates the rate of type I collagen fibril formation

Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) Antigen Profile

Protein Summary

Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling.

Gene names and symbols associated with CHI3L1

  • chitinase-like 1 (Chil1) antibody
  • chitinase 3 like 1 (CHI3L1) antibody
  • chitinase 3-like 1 (cartilage glycoprotein-39) (CHI3L1) antibody
  • chitinase 3 like 1 (Chi3l1) antibody
  • ASRT7 antibody
  • AW208766 antibody
  • BP40 antibody
  • Brp39 antibody
  • CGP-39 antibody
  • Chil1 antibody
  • CLP-1 antibody
  • GP-39 antibody
  • GP38K antibody
  • GP39 antibody
  • HC-gp39 antibody
  • HCGP-3P antibody
  • hCGP-39 antibody
  • MGP-40 antibody
  • SPC-40 antibody
  • SPS-40 antibody
  • YKL-40 antibody
  • YKL40 antibody
  • YYL-40 antibody

Protein level used designations for CHI3L1

CGP-39 , GP-39 , cartilage glycoprotein 39 , chitinase-3-like protein 1 , 39 kDa synovial protein , 38 kDa heparin-binding glycoprotein , signal-processing protein , 39 kDa whey protein , 40 kDa secretory signalling glycoprotein , cartilage glycoprotein-39 , chitinase-like protein 1 , signal processing protein , chitinase 3-like 1 protein , mammary gland protein 40

GENE ID SPECIES
12654 Mus musculus
1116 Homo sapiens
396865 Sus scrofa
286869 Bos taurus
89824 Rattus norvegicus
100860825 Capra hircus
443279 Ovis aries
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