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Potential effector of the planar cell polarity signaling pathway. Additionally we are shipping Chromosome 1open Reading Frame 89 Antibodies (9) and many more products for this protein.
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RSG1 localizes to the mother centriole in a process that depends on tau tubulin kinase 2 (TTBK2 (show TTBK2 Proteins)), the CPLANE complex protein Inturned (INTU (show INTU Proteins)), and its own GTPase (show RACGAP1 Proteins) activity. The data suggest a specific role for RSG1 in the final maturation of the mother centriole and ciliary vesicle that allows extension of the ciliary axoneme.
Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells (By similarity).
REM2- and Rab-like small GTPase 1
, Rem/Rab-Similar GTPase 1
, miro domain-containing protein C1orf89
, miro domain-containing protein C1orf89 homolog