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Four alternatively spliced transcript variants encoding four different isoforms have been found for this nuclear gene. Additionally we are shipping C21orf2 Antibodies (23) and many more products for this protein.
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Four alternatively spliced transcript variants encoding four different isoforms have been found for this nuclear gene. All isoforms contain leucine-rich repeats. Three of these isoforms are mitochondrial proteins and one of them lacks the target peptide, so is not located in mitochondrion. This gene is down-regulated in Down syndrome (DS) brain, which may represent mitochondrial dysfunction in DS patients.
hypothetical protein LOC394810
, hypothetical protein LOC424866
, nuclear encoded mitochondrial protein C21orf2