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C9ORF24 encodes a nuclear- or perinuclear-localized protein with no predicted domains or similarity to other known proteins.
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Our data strongly suggest an influence of CBE1 in ciliogenesis in spermatids due to the localization at the microtubules of the elongating spermatids, indicating a role in the intramanchette and/or intraflagellar transport mechanism.
CBE1 may play an important role in the differentiation and/or function of ciliated cells in human airways
Chronological regulation of CBE1/Cbe1 expression during pulmonary differentiation suggests involvement in ciliogenesis, with an additional role during early lung development.
SMRP1 was localized to the cytoplasm of step 9-12 elongated spermatids. The protein appeared in a cap formation that covered the caudal sides of the elongated nuclei.
1110017D15Rik is most abundantly expressed in tissues rich in highly ciliated cells, such as olfactory sensory neurons, and is predicted to be important to cilia.
This gene encodes a nuclear- or perinuclear-localized protein with no predicted domains or similarity to other known proteins. Expression of this gene is induced during the differentiation of bronchial epithelial cells, and the encoded protein may play a role in ciliogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
ciliated bronchial epithelial protein 1
, spermatid-specific manchette-related protein 1
, testes development-related NYD-SP22
, ciliated bronchial epithelium 1
, testis development protein NYD-SP22
, likely ortholog of H. sapiens chromosome 9 open reading frame 24 (C9orf24)
, spermatid specific manchette related protein 1