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Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Additionally we are shipping Chymotrypsin-Like Elastase Family, Member 1 Antibodies (51) and Chymotrypsin-Like Elastase Family, Member 1 Kits (23) and many more products for this protein.
Showing 10 out of 14 products:
A heterozygous frameshift variant c.419delC in exons of the CELA1 gene identified in all punctate palmoplantar keratoderma patients.
Inverse association of HbA1c with faecal elastase 1 in people without diabetes suggests that pancreatic exocrine dysfunction might be an early disturbance that develops in parallel with hyperglycemia.
Results indicate that the extract of the mycelium of Tricholoma matsutake decreased elastase activity in a dose-dependent manner and reduced the levels of matrix metalloproteinase 1 (MMP-1 (show MMP1 Proteins)).
Mutant genes (CELA1, HSPG2, and KCNK5) in Balkan endemic nephropathy patients encode proteins involved in basement membrane/extracellular matrix and vascular tone, tightly connected to process of angiogenesis.
The stretch-dependent expression and binding kinetics of Cela1 indicate an important role in stretch-dependent remodeling of the peripheral lung during development and regeneration.
defines the temporal-spatial pattern of elastin (show ELN Proteins) remodeling during lung development, demonstrates an association of this remodeling with chymotrypsin-like elastase 1
Glucocorticoid receptor (show NR3C1 Proteins)-null lungs included Chi3l3 (show CHI3L3 Proteins) (11-fold, P < 0.05), a macrophage inflammatory response gene and Ela1 (9.4-fold, P < 0.05), an extracellular matrix remodeling enzyme.
insights into the PPE and HNE (show ELANE Proteins) inhibition
Here, we studied the priming of SARS (show SARS Proteins)-CoV S by elastase and show an important role for residue Thr (show TRH Proteins)(795) in the S2 domain.
comparison of x-ray structures of alpha1PI complexes with trypsin, PPE, and human neutrophil elastase (show ELANE Proteins)
the oxygen of the oxopropyl group of the inhibitor is present as an oxygen anion rather than a hydroxyl group, supporting the role of the "oxyanion hole" in stabilizing the tetrahedral intermediate in ELS1 catalysis
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas or fecal material is actually referring to chymotrypsin-like elastase family, member 3B.
chymotrypsin-like elastase family member 1
, elastase 1, pancreatic
, pancreatic elastase 1
, chymotrypsin-like elastase family, member 1
, pancreatic elastase I
, elastase I