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The protein encoded by CTRB1 is one of a family of serine proteases that is secreted into the gastrointestinal tract as an inactive precursor, which is activated by proteolytic cleavage with trypsin.. Additionally we are shipping Chymotrypsinogen B1 Antibodies (70) and and many more products for this protein.
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Data show that alpha-chymotrypsin (alpha-CT) can be activated by pressure on negatively charged surfaces like quartz and poly(styrene sulfonate) (PSS).
Changes in stability of the native state, and not specific interference with molecular mechanism, are the dominant cause of mutant-based effects on polymerization of bovine alpha1-chymotrypsin mutants.
report studies of hydration dynamics at the surface of bovine pancreatic alpha-chymotrypsin
The formation of non-soluble complexes between a positively charged protein and a strong anionic polyelectrolyte, chymotrypsin, and poly vinyl sulfonate, respectively, was studied under different experimental conditions.
CTRB1 protects against secretagogue-induced pancreatitis by reducing trypsin activity.
An inversion in the CTRB1-CTRB2 locus modifies risk for Alcoholic and Non-alcoholic Chronic Pancreatitis indicating that common pathomechanisms are involved in these inflammatory disorders.
Two protective, low-frequency, non-synonymous variants were significantly associated with a decrease in age-related macular degeneration (AMD)risk: A307V in PELI3 and N1050Y in CFH .We also identified a strong protective signal for a common variant (rs8056814) near CTRB1 associated with a decrease in AMD risk (logistic regression: OR = 0.71, P = 1.8 x 10-07).
The protein encoded by this gene is one of a family of serine proteases that is secreted into the gastrointestinal tract as an inactive precursor, which is activated by proteolytic cleavage with trypsin.
, chymotrypsin B1
, chymotrypsinogen B1
, chymotrypsinogen 1
, chymotrypsinogen 2
, chymotrypsinogen B2
, Chymotrypsin B
, Chymotrypsinogen 2