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Promotes the degradation of p53/TP53 protein and inhibits its transactivity (By similarity). Additionally we are shipping CCDC106 Kits (12) and CCDC106 Proteins (5) and many more products for this protein.
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Our studies revealed that CCDC106 is associated with non-small cell lung cancer progression and unfavorable prognosis. CCDC106 enhanced Cyclin A2 (show CCNA2 Antibodies) and Cyclin B1 (show CCNB1 Antibodies) expression and promoted A549 and H1299 cell proliferation, which depended on AKT (show AKT1 Antibodies) signaling. These results suggest that CCDC106 may be a novel target for lung cancer treatment.
CCDC106 promotes the degradation of p53 (show TP53 Antibodies) protein and inhibits its transactivity.
Promotes the degradation of p53/TP53 protein and inhibits its transactivity (By similarity).
coiled-coil domain-containing protein 106
, coiled-coil domain containing 106
, protein predicted by clone 23882