Collagen, Type IV, alpha 6 (COL4a6) ELISA Kits

COL4a6 encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Additionally we are shipping COL4a6 Antibodies (54) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
COL4a6 1288 Q14031
Anti-Mouse COL4a6 COL4a6 94216  
Anti-Rat COL4a6 COL4a6 363458  
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Top COL4a6 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 3.1 ng/mL 12.5-800 ng/mL   96 Tests 15 to 18 Days
$910.56
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More ELISA Kits for COL4a6 Interaction Partners

Human Collagen, Type IV, alpha 6 (COL4a6) interaction partners

  1. These findings indicate that alpha112:alpha556 (IV) network, which is the only network that includes the alpha6(IV) chain, is one regulator of KRT10 expression in keratinization of oral mucosal epithelium.

  2. although alpha5 and alpha6 (IV) chains are induced in the glomerular basement membrane in autosomal recessive Alport syndrome, their induction does not seem to play a major compensatory role

  3. deletion breakpoints in five Alport syndrome-diffuse leiomyomatosis patients and show a contiguous COL4A6/COL4A5 deletion in each case, were characterized.

  4. Mutation in COL4A6 gene is associated with gastric cancer peritoneal carcinomatosis.

  5. The expression of collagen type IV and its alpha chains (alpha1-6) was investigated in different endothelial cell culture systems in vitro qualitatively and quantitatively.

  6. New deletion in COL4A6/COL4A5 related to diffuse esophageal leiomyomatosis associated with Alport syndrome in a Chinese family.

  7. COL4A6 is associated with X-linked nonsyndromic hearing loss.

  8. We showed that TPM2, CLU, and COL4A6 mRNA levels are downregulated in prostate cancer.

  9. In this paper we improve the definition of the COL4A5/COL4A6 deletions in three Alport syndrome with diffuse leiomyomatosis.

  10. The expression of Col I, Col IV and Fn was closely related to tumor invasion, the regional lymph node metastasis and other pathological features in laryngeal squamous cell carcinoma.

  11. expression of collagen type IV alpha6 chain in the smooth muscle BM of the gastrointestinal tract is restricted to the esophagus in humans

  12. The expression of collagen type IV was significantly decreased in colorectal cancer tissues.

  13. We provide a first indication that highly specialized patterns characteristic of COL4A5-COL4A6 expression in vivo arise from effects of distributed cis-acting regulatory elements on a bidirectional proximal promoter, itself transcriptionally competent.

  14. Collagen chains alpha5(IV) and alpha6(IV) were frequently absent in basement membrane from pancreatic adenocarcinoma, and their absence might be related to the invasion of cancer cells.

  15. Enhanced expression of collagen type IV is associated with liver metastases from gastrointestinal tumours

  16. The expression of the alpha5(IV)/alpha6(IV) chains was down-regulated in colorectal cancer, and the loss of expression of the alpha5(IV)/alpha6(IV) chains was associated with the hypermethylation of their promoter region.

  17. This study showed that in some cases of esophageal squamous cell carcinoma the alpha5/alpha6 (IV) chains are expressed linearly around the cancer cell nests and the alpha5/alpha6 (IV) chain expression is one prognostic factor of ESCC.

  18. Type IV collagen alpha6 chain-derived noncollagenous domain 1 (alpha6NC1) is an endogenous inhibitor of angiogenesis and tumor growth.

  19. Meningiomas increase in size through increased production of extracellular matrix; furthermore, the proliferation of cells typically associated with neoplasia requires considerable interaction with the extracellular matrix.

  20. Results suggest that the down-regulation of alpha 6(IV) mRNA coincides with the acquisition of invasive growth properties, whereas alpha1(IV) and alpha1(VII) mRNAs were up-regulated already in dysplastic tissue.

Mouse (Murine) Collagen, Type IV, alpha 6 (COL4a6) interaction partners

  1. These findings indicate that alpha112:alpha556 (IV) network, which is the only network that includes the alpha6(IV) chain, is one regulator of KRT10 expression in keratinization of oral mucosal epithelium.

  2. although alpha5 and alpha6 (IV) chains are induced in the glomerular basement membrane in autosomal recessive Alport syndrome, their induction does not seem to play a major compensatory role

  3. In murine embryos, collagen IV subunits alpha1(IV), alpha2(IV), alpha5(IV) and alpha6(IV) were detected in the basement membrane surrounding the lens vesicle, and they persisted in the capsule until adulthood.

  4. the proximal bifunctional promoter regulates the expression of the alpha5(IV) and alpha6(IV) genes in a cell-specific manner and demonstrates promoter plasticity in growth factor regulation of type IV collagen genes in different tissues of the body.

Zebrafish Collagen, Type IV, alpha 6 (COL4a6) interaction partners

  1. the shiomaneki (sio) gene locus encodes Col4a6, a subunit of type IV collagen, which, in a complex with Col4a5, is a basement membrane (BM) component. Both col4a5 and col4a6 mutants displayed similar abnormalities in the axogenesis

  2. the collagen IV sheet anchors secreted factors at the surface of the tectum, which serve as guidance cues for retinal axons.

COL4a6 Antigen Profile

Antigen Summary

This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Two splice variants have been identified for this gene.

Gene names and symbols associated with COL4a6

  • collagen type IV alpha 6 chain (COL4A6) antibody
  • collagen, type IV, alpha 6 (Col4a6) antibody
  • collagen, type IV, alpha 6 (col4a6) antibody
  • collagen, type IV, alpha 6 (COL4A6) antibody
  • collagen type IV alpha 6 chain (col4a6) antibody
  • collagen type IV alpha 6 chain (Col4a6) antibody
  • BB116301 antibody
  • CXDELq22.3 antibody
  • DELXq22.3 antibody

Protein level used designations for COL4a6

collagen IV, alpha-6 polypeptide , collagen alpha-6(IV) chain , collagen of basement membrane, alpha-6 , dJ889N15.4 (Collagen Alpha 6(IV)) , procollagen type IV alpha 6 , procollagen, type IV, alpha 6 , collagen type IV alpha 6 chain , collagen, type IV, alpha 6 , type IV alpha 6 collagen , type IV collagen alpha 6 chain , collagen alpha-6(IV) chain-like , LOW QUALITY PROTEIN: collagen alpha-6(IV) chain

GENE ID SPECIES
1288 Homo sapiens
94216 Mus musculus
403840 Canis lupus familiaris
422350 Gallus gallus
465804 Pan troglodytes
523526 Bos taurus
554268 Danio rerio
703707 Macaca mulatta
100152680 Sus scrofa
100338437 Oryctolagus cuniculus
100479688 Ailuropoda melanoleuca
100493153 Xenopus (Silurana) tropicalis
100554629 Anolis carolinensis
100587255 Nomascus leucogenys
363458 Rattus norvegicus
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