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COL18A1 encodes the alpha chain of type XVIII collagen. Additionally we are shipping COL18A1 Kits (91) and COL18A1 Proteins (24) and many more products for this protein.
Showing 10 out of 189 products:
Human Polyclonal COL18A1 Primary Antibody for IF (p), IHC (p) - ABIN669951
Gao, Zhao, Liang, Li, Cao, Liu: Effect of peritoneal dialysis on expression of vascular endothelial growth factor, basic fibroblast growth factor and endostatin of the peritoneum in peritoneal dialysis patients. in Nephrology (Carlton, Vic.) 2011
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Human Monoclonal COL18A1 Primary Antibody for IA, IHC (fro) - ABIN2192047
Deininger, Fimmen, Kremsner, Meyermann, Schluesener: Accumulation of endostatin/collagenXVIII in brains of patients who died with cerebral malaria. in Journal of neuroimmunology 2002
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Human Monoclonal COL18A1 Primary Antibody for IHC (p), WB - ABIN448134
Chen, Hsu, Song, Huang, Tsai, Kuo, Hsu, Tsai, Tsai, Woung, Chiou, Lu, Chen: Celecoxib enhances radiosensitivity in medulloblastoma-derived CD133-positive cells. in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2010
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Chicken Monoclonal COL18A1 Primary Antibody for ELISA, WB - ABIN265797
Jung, Lim: The antiangiogenic and antinociceptive activities of n-propyl gallate. in Phytotherapy research : PTR 2011
Increased serum levels of endostatin were associated with loss of graft function in kidney transplant recipients.
endostatin may have a role in subclinical atherosclerosis as shown in a study of a healthy Japanese population
a protease capable of producing endostatin from human Col (show HDAC1 Antibodies) XVIII, is reported
Structural and biological functions of COL18A1, such as its requirement in the maintenance of basement membrane integrity and its emerging roles in regulating cell survival, stem or progenitor cell maintenance and differentiation and inflammation have been reported. (Review)
Lower endostatin levels or a predominance of VEGF (show VEGFA Antibodies) over endostatin are predictors of poor short-term prognosis of intracranial atherosclerotic stenosis.
We further show that the SAGA deubiquitinase-activated gene Multiplexin (Mp) is required in glia for proper photoreceptor axon targeting. Mutations in the human ortholog of Mp, COL18A1, have been identified in a family with a SCA7-like progressive visual disorder, suggesting that defects in the expression of this gene in SCA7 patients could play a role in the retinal degeneration that is unique to this ataxia.
Two COL18A1 variants co-segregated with familial epilepsy and anterior polymicrogyria in a family.
Blood endostatin wasdddddddddddddddddddddddddf significantly higher in chronic hepatitis C patients with liver fibrosis compared to those without fibrosis.
The homozygous DN and NN genotypes of COL18A1 D104N were associated with the risk of osteosarcoma.
Endostatin is increased in patients with primary sjogren's syndrome patients with interstitial lung disease.
Together these data suggest that Lh3 (show PLOD3 Antibodies)-Collagen18A1 dependent ECM (show MMRN1 Antibodies) modifications regulate the transition of trunk neural crest cells from a non-segmental sheet like migration mode to a segmental stream migration mode
These results provide important insight into the biological function and regulation of COL18A1, and point to additional sequences that may contribute to complex diseases involving COL18A1.
diwanka (lh3 (show PLOD3 Antibodies)) acts through myotomal type XVIII collagen, a ligand for neural-receptor protein tyrosine phosphatases that guide motor axons
Investigate the timecourse of collagen XVIII processing with release of endostatin (ES) and other low-molecular-weight fragments during early ischemia-reperfusion of the heart.
This study examined the staining levels of proteasomal and autophagy markers in the RPE (show RPE Antibodies) of different ages of the Col18a1 (-/-) mice. Eyes from 3, 6-7, 10-13 and 18 months old mice were enucleated and embedded in paraffin according to the routine protocol.
Kidney fibrosis in aging may represent a natural outcome of upregulated endostatin (EST (show MAP3K8 Antibodies)) and transglutaminase 2 (TG2 (show TGM2 Antibodies)), but more likely it appears to be a result of cumulative stresses occurring on the background of synergistically acting geronic (aging) proteins, EST (show MAP3K8 Antibodies) and TG2 (show TGM2 Antibodies).
There are correlations between the elevation of endostatin levels and parallel microvascular rarefaction and induction of renal fibrosis in aging mice.
An excess of the collagen XVIII Tsp-1 (show GZMA Antibodies) domain is deleterious in the eye, possibly by impairing certain functions of the full-length molecule.
The results of the present study indicate endostatin promotes soft callus formation but inhibits callus remodeling during fracture healing most probably by an inhibition of angiogenesis.
Data indicate that delivery by attenuated Salmonella of the combination therapeutic plasmid simultaneously knocked down the expression of Stat3 (show STAT3 Antibodies) and resulted in over-expression of Endostatin, which synergistically inhibited prostate cancer growth.
Endostatin lowers blood pressure via nitric oxide and prevents hypertension associated with VEGF (show VEGFA Antibodies) inhibition
Women with early-onset, but not late-onset preeclampsia have higher levels of endostatin than healthy pregnant women in corresponding lengths of gestation.
In vivo, Collagen XVIII/endostatin does not play an indispensable role in skeletal development
Lack of collagen XVIII/endostatin results in eye abnormalities.
This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, collagen alpha-1(XVIII) chain
, multi-functional protein MFP
, procollagen, type XVIII, alpha 1
, collagen, type XVIII, alpha 1
, alpha 1 type XVIII collagen
, collagen alpha-1(XVIII) chain-like
, LOW QUALITY PROTEIN: collagen alpha-1(XVIII) chain