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The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Additionally we are shipping Cystatin C Kits (124) and Cystatin C Proteins (74) and many more products for this protein.
Showing 10 out of 462 products:
Human Monoclonal CST3 Primary Antibody for ELISA, WB - ABIN1045447
Shlipak, Katz, Kestenbaum, Fried, Newman, Siscovick, Stevens, Sarnak: Rate of kidney function decline in older adults: a comparison using creatinine and cystatin C. in American journal of nephrology 2009
Show all 17 Pubmed References
Human Monoclonal CST3 Primary Antibody for ELISA, WB - ABIN969070
Helisalmi, Väkevä, Hiltunen, Soininen: Flanking markers of cystatin c (CST3) gene do not show association with Alzheimer's disease. in Dementia and geriatric cognitive disorders 2009
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Human Monoclonal CST3 Primary Antibody for ELISA, WB - ABIN965940
Aubin, Labelle, Chevrefils, Desroches, Clin, Eng: Preoperative planning simulator for spinal deformity surgeries. in Spine 2008
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Human Monoclonal CST3 Primary Antibody for IHC, IHC (p) - ABIN4301883
Gren, Janciauskiene, Sandeep, Jonigk, Kvist, Gerwien, Håkansson, Grip: The protease inhibitor cystatin C down-regulates the release of IL-β and TNF-α in lipopolysaccharide activated monocytes. in Journal of leukocyte biology 2016
Human Polyclonal CST3 Primary Antibody for IHC, IHC (p) - ABIN4301882
Wu, Hsu, Chen, Yu, Chang, Tai, Liu, Su, Chang, Yu: Candidate serological biomarkers for cancer identified from the secretomes of 23 cancer cell lines and the human protein atlas. in Molecular & cellular proteomics : MCP 2010
Mouse (Murine) Polyclonal CST3 Primary Antibody for ELISA, WB - ABIN249523
Huh, Nagle, Kozak, Abrahamson, Karlsson: Structural organization, expression and chromosomal mapping of the mouse cystatin-C-encoding gene (Cst3). in Gene 1995
Human Polyclonal CST3 Primary Antibody for ELISA, WB - ABIN439722
Mi, Pawlik, Sastre, Jung, Radvinsky, Klein, Sommer, Schmidt, Nixon, Mathews, Levy: Cystatin C inhibits amyloid-beta deposition in Alzheimer's disease mouse models. in Nature genetics 2007
Human Monoclonal CST3 Primary Antibody for IA, ELISA - ABIN2473152
Young, Kandarian, Kurowski: Skeletal muscle glucose uptake following overload-induced hypertrophy. in Life sciences 1992
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Human Monoclonal CST3 Primary Antibody for IA, ELISA - ABIN2473150
Mussap, Plebani: Biochemistry and clinical role of human cystatin C. in Critical reviews in clinical laboratory sciences 2004
Serum and urine levels of cystatin C were significantly higher in children with acute kidney injury. [Review and Meta-Analysis]
Circulating CysC and Gal-3 (show LGALS3 Antibodies) were associated with greater left atrial dilatation in patients with heart failure with reduced left ventricular ejection fraction.
Application of the cystatin C-based equations most accurately estimate glomerular filtration rate in Chinese patients with chronic kidney disease.
This study tested the utility of neutrophil gelatinase-associated lipocalin (NGAL (show LCN2 Antibodies)) and cystatin C (CysC) in addition to standard creatinine for early determination of Acute Kidney Injury (AKI) After Heart Operations Using Cardiopulmonary Bypass. The results support the notion that CysC and NGAL (show LCN2 Antibodies) should be viewed as comparable for early AKI detection.
The strong association between epicardial adipose tissue (EAT) and cystatin C demonstrated herein indicates that EAT accumulation may play an important role in Cystatin C secretion, possibly contributing to cardiometabolic risk in T2DM patients.
A high CysC level had predictive value regarding the severity of vascular lesions in acute coronary syndrome.
Elevated levels of cystatin C were detected in early diagnosis of right heart failure in patients with systemic sclerosis.
Data suggest that melanoma cells internalize/absorb cystatin C from culture media, leading to increased intracellular cystatin C levels; cystatin E/M (show CST6 Antibodies) is internalized as well but at modest rate due to down-regulation of cell migration; however, the effect of intracellular cystatin E/M (show CST6 Antibodies) on down-regulation of legumain (show LGMN Antibodies) activity is pronounced.
An elevated preoperative Cys (show DNAJC5 Antibodies)-C level was demonstrated to be related with worse survival in patients with renal cell carcinoma (show MOK Antibodies)(RCC (show XRCC1 Antibodies)). Measuring preoperative serum Cys (show DNAJC5 Antibodies)-C might be a simple way for finding poor prognostic patients and patients with elevated preoperative Cys (show DNAJC5 Antibodies)-C level should be more closely followed up
Acute kidney injury is common following deliberate self-poisoning with a combination washing powder containing oxalic acid and potassium permanganate and cystatin C monitoring may under estimate the severity of poisoning.
CysC plays an important regulatory role in combating cell death via the autophagic pathway in atherosclerosis.
Data (including data from studies in mutant mice) suggest that up-regulation of Cst3, as observed in plasma of mice with type 2 diabetes, down-regulates insulin (show INS Antibodies) signaling and promotes endoplasmic reticulum stress in hepatocytes but not in myotubes.
Cystatin C is a potential pathogenic signal triggering neurodegeneration in multiple system atrophy.
The neuroprotective activity of CysC against Amyotrophic lateral sclerosis-linked mutant Cu/Zn-superoxide dismutase (SOD1 (show SOD1 Antibodies))-mediated toxicity.
an important role for macrophages, DC, and ROS (show ROS1 Antibodies) in diseases associated with the protease inhibitory activity or amyloidogenic properties of cystatin C.
APP (show APP Antibodies) expression stimulates NSPC proliferation; this effect is mediated via an increase in cystatin C secretion
Cystatin C, a protein targeted to the classical secretory pathway by its signal peptide sequence, is secreted by primary neurons in at least 9 different cystatin C glycoforms associated with exosomes.
The lack of cystatin C enhances Collagen-induced arthritis and primarily affects in vivo priming of the immune system
Inflammation causes downregulation of cystatin C expression in dendritic cells and reduces serum CstC levels.
Data show that the absence of cystatin C reduced epithelial cell apoptosis but increased proliferation in skin.
CST3 may be required to remodel endometrial and placental tissues for close apposition between maternal and fetal vasculatures and to facilitate transplacental transport of gases, micronutrients (amino acids, glucose), and macromolecules (proteins).
Increased production of cystatin C in osteoarthritis synovium does not alleviate synovitis or cartilage pathology.
Cystatin C in milk basic protein (MBP (show MBP Antibodies)) is suggested as one of the factors inhibiting bone resorption
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease.
, egg-white cystatin
, cystatin C
, cystatin 3
, hypothetical protein
, bA218C14.4 (cystatin C)
, neuroendocrine basic polypeptide
, Cystatin C (cysteine proteinase inhibitor)
, colostrum thiol proteinase inhibitor
, cystatin C (amyloid angiopathy and cerebral hemorrhage)