anti-Cystatin C (CST3) Antibodies

Human Cystatin C (CST3) interaction partners

1. bladder cancer (BCa (show BLNK Antibodies)) patients have lower serum cysC concentration than the control group. Serum cysC may be considered as a potential marker of BCa (show BLNK Antibodies) but not its aggressiveness.

2. Postoperative serum Cystatin C, IL-18 (show IL18 Antibodies) and Uric acid after 24h were significantly associated with acute kidney injury

3. Serum CysC is a strong predictor of AKI and the short-term prognosis of CCU patients.

4. Neutrophil gelatinase-associated lipocalin (show LCN2 Antibodies) concentrations in the urine and serum on the second day of intensive care unit admission could be used to predict the development of acute kidney injury in the following three to seven days in the intensive care unit; however, the cystatin C concentration did not have predictive value

5. Study demonstrated that the binding of CST3 and PSAP (show PSAP Antibodies) decreased the inhibitory effects of CST3 on proteinase in vitro. The co-localization of both proteins was detected in cultured cells and in Bunina body-containing motor neurons from patients with amyotrophic lateral sclerosis, suggesting that they might be involved in the process of Bunina body formation.

6. elevated cystatin C is independently associated with adverse vascular outcomes in people with suspected or established CAD (show CAD Antibodies) in terms of all-cause mortality, cardiovascular mortality, and total adverse vascular events [meta-analysis]

7. Cognitive function was significantly and inversely associated with cystatin C and microalbuminuria, in the relatively younger general Japanese population.

8. We enrolled 43 stable coronary artery disease (CAD (show CAD Antibodies)) male patients to examine the relationship between cystatin C-adiponectin (CysC-APN (show ANPEP Antibodies)) complex and coronary plaque characteristics. In multivariate analysis, CysC-APN (show ANPEP Antibodies) complex levels were identified as the strongest negative factor for fibrotic components and the strongest positive factor for both necrotic and lipidic plus necrotic components.

9. Urinary cystatin C is an independent risk predictor in patients with acute myocardial infarction.

10. serum Cys (show DNAJC5 Antibodies)-C levels predict renal function in patients with prostate neoplasia, but were not a biomarker for the development of prostate neoplasia, and were not correlated with the clinicopathological characteristics of prostate cancer .

Mouse (Murine) Cystatin C (CST3) interaction partners

1. CysC plays an important regulatory role in combating cell death via the autophagic pathway in atherosclerosis.

2. Data (including data from studies in mutant mice) suggest that up-regulation of Cst3, as observed in plasma of mice with type 2 diabetes, down-regulates insulin (show INS Antibodies) signaling and promotes endoplasmic reticulum stress in hepatocytes but not in myotubes.

3. Cystatin C is a potential pathogenic signal triggering neurodegeneration in multiple system atrophy.

4. The neuroprotective activity of CysC against Amyotrophic lateral sclerosis-linked mutant Cu/Zn-superoxide dismutase (SOD1 (show SOD1 Antibodies))-mediated toxicity.

5. an important role for macrophages, DC, and ROS (show ROS1 Antibodies) in diseases associated with the protease inhibitory activity or amyloidogenic properties of cystatin C.

6. APP (show APP Antibodies) expression stimulates NSPC proliferation; this effect is mediated via an increase in cystatin C secretion

7. Cystatin C, a protein targeted to the classical secretory pathway by its signal peptide sequence, is secreted by primary neurons in at least 9 different cystatin C glycoforms associated with exosomes.

8. The lack of cystatin C enhances Collagen-induced arthritis and primarily affects in vivo priming of the immune system

9. Inflammation causes downregulation of cystatin C expression in dendritic cells and reduces serum CstC levels.

10. Data show that the absence of cystatin C reduced epithelial cell apoptosis but increased proliferation in skin.

Pig (Porcine) Cystatin C (CST3) interaction partners

1. CST3 may be required to remodel endometrial and placental tissues for close apposition between maternal and fetal vasculatures and to facilitate transplacental transport of gases, micronutrients (amino acids, glucose), and macromolecules (proteins).

Rabbit Cystatin C (CST3) interaction partners

1. Increased production of cystatin C in osteoarthritis synovium does not alleviate synovitis or cartilage pathology.

Cow (Bovine) Cystatin C (CST3) interaction partners

1. Cystatin C in milk basic protein (MBP (show MBP Antibodies)) is suggested as one of the factors inhibiting bone resorption