anti-Cystatin F (Leukocystatin) (CST7) Antibodies

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Additionally we are shipping CST7 Proteins (16) and CST7 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CST7 8530 O76096
CST7 13011 O89098
CST7 296257  
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Top anti-CST7 Antibodies at

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Mouse Goat Un-conjugated ELISA, WB ABIN184745 staining (2µg/ml) of NSO lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg 6 to 7 Days
Human Mouse Un-conjugated WB 100 μL 14 to 16 Days
Human Rabbit Un-conjugated ELISA, IHC, WB Western blot analysis of CST7 using Jurkat whole cell lysates ABIN6279337 at 1/100 staining Human Melanoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11 to 12 Days
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded CL1-5 xenograft, using cystatin F, antibody at 1:500 dilution. WB Image Sample (30 ug of whole cell lysate) A: A549 B: MCF-7 12% SDS PAGE antibody diluted at 1:1000 100 μL 3 to 4 Days
Human Rabbit Un-conjugated WB Western blot analysis of extract of Raji and MCCF7 cells, using CST7 antibody. 100 μL 11 to 13 Days
Human Rabbit Un-conjugated WB Western blot analysis of Cystatin F expression in Raji (A), MCF7 (B) whole cell lysates. 100 μL 11 to 18 Days
Human Rabbit Un-conjugated ELISA   100 μL 14 to 16 Days
Mouse Goat Alkaline Phosphatase (AP) ELISA, WB   100 μL 16 Days
Mouse Goat APC ELISA, WB   100 μL 16 Days
Mouse Goat FITC ELISA, WB   100 μL 16 Days

Top referenced anti-CST7 Antibodies

  1. Mouse (Murine) Polyclonal CST7 Primary Antibody for ELISA, WB - ABIN249525 : Morita, Yoshiuchi, Arakawa, Nishimura: CMAP: a novel cystatin-like gene involved in liver metastasis. in Cancer research 1999 (PubMed)

More Antibodies against CST7 Interaction Partners

Human Cystatin F (Leukocystatin) (CST7) interaction partners

  1. during monocyte to macrophage differentiation, the endosomal/lysosomal proteolytic activity can be regulated by cystatin F whose expression is under the control of transcriptional factor C/EBP alpha.

  2. Regulation of cathepsins S and L by cystatin F during maturation of dendritic cells.

  3. Transgenic cystatin F is expressed in model mice only during demyelination; in chronic demyelination, remyelinating ability is lost.

  4. cystatin F is an intracellular cysteine peptidase inhibitor with readily regulated expression

  5. CST7 is secreted, but artificial modification of its C-terminus can induce its endocytic targeting.

  6. Cystatin F was not colocalized with cystatin C shich suggests distinct functions for these two cysteine protease inhibitors in U937 cells.

  7. analysis of reduction-dependent activation of human cystatin F

  8. A latent protease inhibitor which is itself regulated by proteolysis in the endocytic pathway.

  9. Data demonstrate the addition of N-linked sugars to an Asn-X-Cys motif in cystatin F and suggest that the mannose 6-phosphate sorting machinery is used to divert cystatin F from the secretory pathway and to mediate its uptake from extracellular pools.

Mouse (Murine) Cystatin F (Leukocystatin) (CST7) interaction partners

  1. High CST7 expression is associated with Alzheimer's disease.

  2. Our results validate cystatin F as a useful biomarker of early pathogenesis in experimental models of prion disease, and point to unexpected species-specific differences in the transcriptional responses to prion infections.

  3. During the active remyelinating phase, both CysF knockdown (CysFKD) and microglial-selective CatC overexpression (CatCOE) showed a worsening of the demyelination in Plp(4e/-) transgenic mice. Conversely, during the chronic demyelinating phase, CatC knockdown (CatCKD) ameliorated the demyelination. Our results suggest that the balance between CatC and CysF expression controls the demyelination and remyelination process.

  4. The cystatin F expression in the activated microglia is closely associated with the effect of the A2A receptors, which may be related to the neuroinflammatory responses occurring during the pathological process.

  5. an inhibitory activity other than cystatin F quenches CatL activity in activated macrophages

  6. Expression of cystatin F indicates ongoing demyelination and remyelination; absence of cystatin F expression indicates cessation of remyelination in the demyelinating area.

  7. The embryo's cystatin C and F expression functions as a protective mechanism against the maternal proteinase cathepsin S.

CST7 Antigen Profile

Protein Summary

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. This gene encodes a glycosylated cysteine protease inhibitor with a putative role in immune regulation through inhibition of a unique target in the hematopoietic system. Expression of the protein has been observed in various human cancer cell lines established from malignant tumors.

Gene names and symbols associated with CST7

  • cystatin F (CST7) antibody
  • Cystatin F (cytf) antibody
  • cystatin F (leukocystatin) (Cst7) antibody
  • cystatin F (Cst7) antibody
  • Cmap antibody
  • CST7 antibody
  • cytf antibody
  • LOC100232568 antibody

Protein level used designations for CST7

cystatin F (leukocystatin) , Cystatin F , cystatin-7 , cystatin-F , cystatin-like metastasis-associated protein , leukocystatin , cystatin 7

740962 Pan troglodytes
100232568 Taeniopygia guttata
100305284 Oncorhynchus mykiss
8530 Homo sapiens
13011 Mus musculus
296257 Rattus norvegicus
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