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CCBL1 encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. Additionally we are shipping CCBL1 Antibodies (69) and CCBL1 Proteins (8) and many more products for this protein.
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One is the native structure with the cofactor in the PLP (show C3 ELISA Kits) form bound to Lys247 with the highest resolution yet available for KAT-I at 1.28 A resolution, and the other with the general PLP (show C3 ELISA Kits)-dependent aminotransferase inhibitor, aminooxyacetate (AOAA) covalently bound to the cofactor at 1.54 A.
KAT I inhibited by equimolar tryptophan and half-life is 69.7 minutes at 65 degree C.
Immunohistochemical analysis revealed the presence of KAT I, II, and III in all examined corneal sections.
CH(3 (show SOX3 ELISA Kits))Hg-S-Cys (show DNAJC5 ELISA Kits) and Cys (show DNAJC5 ELISA Kits)-S-Hg-S-Cys (show DNAJC5 ELISA Kits) are substrates and reversible inhibitors of GTK (show FRK ELISA Kits).
major biological roles of glutamine transaminase K are to maintain low levels of phenylpyruvate and to close the methionine salvage pathway--REVIEW
We found elevated cerebellar KAT-1 activities in post-mortem brain samples from schizophrenic versus normal individuals.
alpha-keto acids generated by transamination/l-amino acid oxidase (show IL4I1 ELISA Kits) activity of the two catechol cysteine S-conjugates are unstable
This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene.
, cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase)
, glutamine transaminase K
, glutamine--phenylpyruvate transaminase
, kynurenine aminotransferase I
, kynurenine--oxoglutarate transaminase 1
, kynurenine--oxoglutarate transaminase I
, beta-lysase, kidney
, cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase)
, glutamine-phenylpyruvate aminotransferase
, kyneurenine aminotransferase
, cysteine conjugate-beta lyase 1
, kynurenine aminotransferase/glutamine transaminase K
, kynurenine--oxoglutarate transaminase 1, mitochondrial