anti-Cytochrome B-245, beta Polypeptide (CYBB) Antibodies

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. Additionally we are shipping CYBB Kits (11) and CYBB Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CYBB 1536 P04839
CYBB 13058 Q61093
CYBB 66021  
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Top anti-CYBB Antibodies at antibodies-online.com

Showing 10 out of 114 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB <b>WB Suggested Anti-CYBB Antibody Titration: </b>1.0ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>THP-1 cell lysate <b>IHC Information: </b>Lung, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)<br> 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF (cc), IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat pancreas labeled with Anti NOX2/gp91phox Polyclonal Antibody, Unconjugated (ABIN750688) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-NOX2/gp91phox Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$318.45
Details
Mouse Mouse Un-conjugated IF, WB Western blot analysis of gp91[phox] on mouse macrophage lysate. Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of gp91[phox] antibody. Immunofluorescent staining of mouse macrophage cells with gp91[phox] antibody. 50 μg Log in to see 6 to 8 Days
$168.74
Details
Human Mouse Un-conjugated ICC, IF, IHC (p), WB 0.1 mL Log in to see 7 to 8 Days
$499.25
Details
Human Mouse Un-conjugated WB 0.1 mL Log in to see 7 to 8 Days
$499.25
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-NOX2/gp91phox antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: JURKAT Cell Lysate Lane 3: MCF-7 Cell Lysate Lane 4: SMMC Cell Lysate Anti-NOX2/gp91phox antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue 100 μg Log in to see 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: CYBB/NOX2 Antibody [NBP2-13037] - Extracts from HT29cells. 0.1 mL Log in to see 7 to 9 Days
$490.19
Details
Human Mouse Un-conjugated IHC (p), WB 0.25 mg Log in to see 6 to 8 Days
$368.50
Details
Human Rabbit Un-conjugated ELISA, IHC (p), WB Western Blot (WB) analysis of K562 cells using gp91-phox Polyclonal Antibody. 100 μL Log in to see 16 Days
$181.73
Details
Human Rabbit Un-conjugated ELISA, WB Western Blot (WB) analysis of specific cells using gp91-phox Polyclonal Antibody. 100 μL Log in to see 16 Days
$181.73
Details

CYBB Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CYBB Antibodies

  1. Human Polyclonal CYBB Primary Antibody for IF (cc), IF (p) - ABIN750688 : Dalaklioglu, Tasatargil, Kale, Tanriover, Dilmac, Erin: Metastatic breast carcinoma induces vascular endothelial dysfunction in Balb-c mice: Role of the tumor necrosis factor-? and NADPH oxidase. in Vascular pharmacology 2013 (PubMed)
    Show all 5 Pubmed References

  2. Mouse (Murine) Monoclonal CYBB Primary Antibody for IF, WB - ABIN968524 : Jacobsen, Skalnik: YY1 binds five cis-elements and trans-activates the myeloid cell-restricted gp91(phox) promoter. in The Journal of biological chemistry 1999 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal CYBB Primary Antibody for IHC (p), WB - ABIN3044252 : Liao, Liu, Guo, Zhang, Zhang: Oxidative burst of circulating neutrophils following traumatic brain injury in human. in PLoS ONE 2013 (PubMed)
    Show all 4 Pubmed References

  4. Human Polyclonal CYBB Primary Antibody for IHC, IHC (p) - ABIN4301440 : Rajtik, Carnicka, Szobi, Giricz, O-Uchi, Hassova, Svec, Ferdinandy, Ravingerova, Adameova: Oxidative activation of CaMKIIδ in acute myocardial ischemia/reperfusion injury: A role of angiotensin AT1 receptor-NOX2 signaling axis. in European journal of pharmacology 2016 (PubMed)
    Show all 3 Pubmed References

  5. Mouse (Murine) Monoclonal CYBB Primary Antibody for IF, WB - ABIN968523 : Suzuki, Kumatori, Haagen, Fujii, Sadat, Jun, Tsuji, Roos, Nakamura: PU.1 as an essential activator for the expression of gp91(phox) gene in human peripheral neutrophils, monocytes, and B lymphocytes. in Proceedings of the National Academy of Sciences of the United States of America 1998 (PubMed)
    Show all 4 Pubmed References

  6. Human Monoclonal CYBB Primary Antibody for ICC, IF - ABIN1042596 : Burritt, Quinn, Jutila, Bond, Jesaitis: Topological mapping of neutrophil cytochrome b epitopes with phage-display libraries. in The Journal of biological chemistry 1995 (PubMed)
    Show all 2 Pubmed References

  7. Human Polyclonal CYBB Primary Antibody for ELISA, IHC - ABIN4301436 : Zhu, Lindsey, Konieczna, Eklund: Constitutive activation of SHP2 protein tyrosine phosphatase inhibits ICSBP-induced transcription of the gene encoding gp91PHOX during myeloid differentiation. in Journal of leukocyte biology 2008 (PubMed)

  8. Human Monoclonal CYBB Primary Antibody for WB - ABIN1042597 : Baniulis, Burritt, Taylor, Dinauer, Heyworth, Parkos, Magnusson, Jesaitis: Monoclonal antibody CL5 recognizes the amino terminal domain of human phagocyte flavocytochrome b558 large subunit, gp91phox. in European journal of haematology 2005 (PubMed)

More Antibodies against CYBB Interaction Partners

Zebrafish Cytochrome B-245, beta Polypeptide (CYBB) interaction partners

  1. The nox1 (show NOX1 Antibodies), nox2/cybb expression in zebrafish during early nervous system development from 12 to 48 hours post fertilization

Rabbit Cytochrome B-245, beta Polypeptide (CYBB) interaction partners

  1. Data indicate that NADPH oxidase (show NOX1 Antibodies) NOx2 inhibition attenuates endoplasmic reticulum (ER) stress and apoptosis.

Human Cytochrome B-245, beta Polypeptide (CYBB) interaction partners

  1. Nox2 activity efficiently contributes to the mechanism of oxidative stress-induced (show SQSTM1 Antibodies) increase in premature aging conferred by doxorubicin. The importance of modulation of Nox2 in human EPCs could reveal a useful tool to restore endothelial progenitor cells physiological function and properties.

  2. We examined the pattern of NOX expression in spinal cords of patients and mouse models of ALS (show IGFALS Antibodies) and analyzed the impact of genetic deletion of the NOX1 (show NOX1 Antibodies) and 2 isoforms as well as pharmacological NOX inhibition in the SOD1 (show SOD1 Antibodies)(G93A) ALS (show IGFALS Antibodies) mouse model.In contrast to previous publications, survival of SOD1 (show SOD1 Antibodies)(G93A) mice was not modified upon breeding with constitutive NOX1 (show NOX1 Antibodies) and NOX2 deficient mice.

  3. Recent studies reveal that AKT2 (show AKT2 Antibodies)-NOX2 signaling has critical roles in Ca mobilization, ROS (show ROS1 Antibodies) generation, degranulation, and control of the ligand-binding function of cell surface molecules, thereby promoting heterotypic cell-cell interactions in thromboinflammation.

  4. Study demonstrate that Nox2 signaling via inactivation of phosphatase and tensin homolog (show PTEN Antibodies) and activation of the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) pathway leads to membrane ruffling and macropinocytosis.

  5. Our findings indicate that Nox2 deficiency results in exaggerated experimental asthma, which is caused by enhanced Th2 effector function in a T-cell-intrinsic manner.

  6. In a family study of a patient with chronic granulomatous disease, the mutation in the CYBB gene was confirmed to be pathogenic, and the three variants in the CYBA (show CYBA Antibodies) gene were benign.

  7. Finally, overexpression of miR34a in EBNA1 (show EBNA-1 Antibodies)-expressing SNU719 cells induced typical apoptosis, suggesting that reactivation of miR34a in EBNA1 (show EBNA-1 Antibodies)-expressing gastric cancer cells could be a strategy for treatment of EBV-infected gastric cancer cells.

  8. NOX2 expression was significantly higher in the cortex of asphyctic suicide subjects than in non-suicidal asphyxia and controls.

  9. Acute myeloid leukemia (show BCL11A Antibodies) cells -derived NOX2 drives transfer of mitochondria via the generation of superoxide.

  10. NOX2, NOX4 (show NOX4 Antibodies), and mitochondrial-derived reactive oxygen species contribute to angiopoietin-1 (show ANGPT1 Antibodies) signaling and angiogenic responses in endothelial cells.

Cow (Bovine) Cytochrome B-245, beta Polypeptide (CYBB) interaction partners

  1. Data indicate that the efficiency of NADPH oxidase (show NOX1 Antibodies) enzymatic activity is higher at endoplasmic reticulum (ER).

  2. A p47(phox) and Src kinase (show CSK Antibodies) activation of peroxide production by Nox2 appears to be an important contributor to vascular contractile mechanisms mediated through activation of protein kinase C (show PKC Antibodies)

Mouse (Murine) Cytochrome B-245, beta Polypeptide (CYBB) interaction partners

  1. this study shows that neutrophil pyroptosis mediates pathology of Pseudomonas aeruginosa lung infection in the absence of the NADPH oxidase (show NOX1 Antibodies) NOX2

  2. Data indicate that increased NADPH oxidase (show NOX1 Antibodies) activity after traumatic brain injury drives M1-like activation in microglia/macrophages that contributes to inflammatory-mediated neurodegeneration.

  3. Neurofibromin (show NF1 Antibodies) regulates macrophage superoxide production via p21Ras.Neurofibromin-deficient smooth muscle cells are sensitive to oxidative stress.NADPH oxidase 2 is required for NF1 (show NF1 Antibodies) arterial stenosis.Neurofibromatosis type 1 patients have evidence of chronic oxidative stress.

  4. We examined the pattern of NOX expression in spinal cords of patients and mouse models of ALS and analyzed the impact of genetic deletion of the NOX1 (show NOX1 Antibodies) and 2 isoforms as well as pharmacological NOX inhibition in the SOD1 (show SOD1 Antibodies)(G93A) ALS mouse model.In contrast to previous publications, survival of SOD1 (show SOD1 Antibodies)(G93A) mice was not modified upon breeding with constitutive NOX1 (show NOX1 Antibodies) and NOX2 deficient mice.

  5. Spinal cord injury leads to a significant increase in NOX2 expression. The reduction in M2 polarization is associated with a peak in NOX2 expression.

  6. NOX2 has a role in leukocyte activation and in thrombus formation

  7. mice deficient in reactive oxygen species production by NOX2 due to the absence of the gp91 (show LILRB3 Antibodies) subunit had significantly more severe pathology in the later stages of infection with Leishmania amazonensis

  8. indicate that following traumatic brain injury NOX2 inhibition promotes a robust anti-inflammatory response in macrophages/microglia that is mediated by the IL-10 (show IL10 Antibodies)/STAT3 (show STAT3 Antibodies) signaling pathway

  9. The results suggest that Nrf2 (show NFE2L2 Antibodies) is an important regulator of the retinal milieu during tissue ischemia, and that the Nrf2 (show NFE2L2 Antibodies)/NOX2 balance may play a critical role in determining the fate of ischemic revascularization.

  10. North American ginseng inhibits myocardial NOX2-ERK1/2 (show MAPK1/3 Antibodies)-TNF-alpha (show TNF Antibodies) signaling pathway and improves cardiac function in endotoxemia, suggesting that NA ginseng may have the potential in the prevention of clinical sepsis.

Pig (Porcine) Cytochrome B-245, beta Polypeptide (CYBB) interaction partners

  1. These results suggested that resveratrol strongly enhances the RA-induced O2(-)-generating activity via up-regulation of gp91-phox gene expression in U937 cells.

  2. sub-vasomotor concentration of ET-1 (show EDN1 Antibodies) leads to vascular dysfunction by impairing endothelium-dependent NO-mediated dilation via p38 (show MAPK14 Antibodies) kinase-mediated production of superoxide from NADPH oxidase (show NOX1 Antibodies) following ETA receptor activation

  3. Reactive oxygen species generated by NADPH oxidase (show NOX1 Antibodies) contribute to the aberrant pulmonary arterial responses in piglets exposed to 3 days of hypoxia.

  4. Upregulation of PPAR-gamma and NADPH oxidases are involved in restenosis.

CYBB Antigen Profile

Protein Summary

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase\; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.

Gene names and symbols associated with CYBB

  • cytochrome b-245, beta polypeptide (chronic granulomatous disease) (cybb) antibody
  • cytochrome b-245, beta polypeptide (cybb) antibody
  • cytochrome b-245 heavy chain (CYBB) antibody
  • cytochrome b-245, beta polypeptide L homeolog (cybb.L) antibody
  • cytochrome b-245, beta polypeptide (CYBB) antibody
  • cytochrome b-245 beta polypeptide (CYBB) antibody
  • cytochrome b-245 beta chain (CYBB) antibody
  • cytochrome b-245, beta polypeptide (Cybb) antibody
  • cytochrome b-245 beta chain (Cybb) antibody
  • cytochrome b-245, beta polypeptide (chronic granulomatous disease) (CYBB) antibody
  • NADPH oxidase heavy chain subunit (GP91-PHOX) antibody
  • AMCBX2 antibody
  • C88302 antibody
  • Cgd antibody
  • CGD91-phox antibody
  • CYBB antibody
  • Cyd antibody
  • GP91-1 antibody
  • Gp91-phox antibody
  • GP91PHOX antibody
  • NOX1 antibody
  • Nox2 antibody
  • p91-PHOX antibody
  • zgc:64144 antibody

Protein level used designations for CYBB

cytochrome b-245, beta polypeptide , gp91 , NADPH oxidase 2 , cytochrome b-245, beta polypeptide (chronic granulomatous disease) , Cytochrome b-245 heavy chain , NADPH oxidase heavy chain subunit , NADPH oxidase 1 , NADPH oxidase flavocytochrome b subunit , cytochrome b-245 heavy chain , gp91-phox , CGD91-phox , cytochrome b(558) subunit beta , cytochrome b558 subunit beta , heme-binding membrane glycoprotein gp91phox , neutrophil cytochrome b 91 kDa polypeptide , p22 phagocyte B-cytochrome , superoxide-generating NADPH oxidase heavy chain subunit , gp91-1 , endothelial type gp91-phox , predicted NADPH oxidase-2

GENE ID SPECIES
393386 Danio rerio
595081 Xenopus (Silurana) tropicalis
696542 Macaca mulatta
444353 Xenopus laevis
100036757 Ovis aries
100270807 Salmo salar
100008801 Oryctolagus cuniculus
1536 Homo sapiens
418581 Gallus gallus
281112 Bos taurus
13058 Mus musculus
66021 Rattus norvegicus
491825 Canis lupus familiaris
397108 Sus scrofa
Selected quality suppliers for anti-CYBB (CYBB) Antibodies
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