anti-DCP2 Decapping Enzyme Homolog (S. Cerevisiae) (DCP2) Antibodies

The protein encoded by DCP2 is a key component of an mRNA-decapping complex required for degradation of mRNAs, both in normal mRNA turnover, and in nonsense-mediated mRNA decay (NMD). Additionally we are shipping DCP2 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DCP2 70640 Q9CYC6
DCP2 167227 Q8IU60
DCP2 291604  
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Top anti-DCP2 Antibodies at antibodies-online.com

Showing 10 out of 62 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-DCP2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Placenta 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-DCP2 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Jurkat cell lysate DCP2 is supported by BioGPS gene expression data to be expressed in Jurkat 100 μL 2 to 3 Days
$319.00
Details
Human Rabbit Un-conjugated IF, ELISA, WB 0.1 mg 2 to 3 Days
$360.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of DCP2 Antibody (Center) (ABIN653129) in HL-60 cell line lysates (35 µg/lane). DCP2 (arrow) was detected using the purified polyclonal antibody. DCP2 Antibody (Center) (ABIN653129) IHC analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of extract of HT29 and rat brain cells, using DCP2 antibody. Immunohistochemistry of paraffin-embedded mouse lung using DCP2 antibody at dilution of 1:100 (x40 lens). 100 μL 11 to 13 Days
$366.77
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$581.17
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-DCP2 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 0.05 mg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL 11 to 14 Days
$484.00
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated IF, IHC, WB Western blot analysis of extracts of various cell lines, using DCP2 antibody. Immunohistochemistry of paraffin-embedded mouse lung using DCP2 antibody. 200 μL 12 to 14 Days
$438.90
Details

Top referenced anti-DCP2 Antibodies

  1. Human Polyclonal DCP2 Primary Antibody for IHC, IHC (p) - ABIN4304526 : Zampedri, Tinoco-Cuellar, Carrillo-Rosas, Diaz-Tellez, Ramos-Balderas, Pelegri, Maldonado: Zebrafish P54 RNA helicases are cytoplasmic granule residents that are required for development and stress resilience. in Biology open 2016 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal DCP2 Primary Antibody for IP, PLA - ABIN445395 : DLima, Ma, Winkler, Chu, Loh, Corpuz, Budnik, Lykke-Andersen, Saghatelian, Slavoff: A human microprotein that interacts with the mRNA decapping complex. in Nature chemical biology 2016 (PubMed)

More Antibodies against DCP2 Interaction Partners

Mouse (Murine) DCP2 Decapping Enzyme Homolog (S. Cerevisiae) (DCP2) interaction partners

  1. results suggest miR-141-3p/200a-3p may be involved in post-transcriptional repression of Dcp2 expression during renal development

  2. ERK-phosphorylated Dcp1a enhances its interaction with the decapping enzyme Dcp2 during early differentiation of 3T3-L1 cells.

  3. Recruitment of DCP1A and DCP2 increases the mRNA degradation capacity of the maturing oocyte so that by the 2-cell stage, most of the maternal mRNA is degraded.

  4. The results showed that DCP1A and DCP2 are critical in the transition from mRNA stability to instability during meiotic maturation and that mRNA degradation must be successful to execute the oocyte-to-zygote transition.

  5. In this study the increase in Irf-7 mRNA within the background of reduced Dcp2 levels was attributed to a stabilization of the Irf-7 mRNA, suggesting that Dcp2 normally modulates Irf-7 mRNA stability.

  6. Like Dcp2, Nudt16 also regulates the stability of a subset of mRNAs including a member of the motin family of proteins involved in angiogenesis.

Human DCP2 Decapping Enzyme Homolog (S. Cerevisiae) (DCP2) interaction partners

  1. Human MARF1 is an endoribonuclease that interacts with the DCP1:DCP2 decapping complex and degrades target mRNAs.

  2. Human Dcp2 levels and activity are controlled by a competition between decapping complex assembly and Dcp2 degradation.

  3. The data indicates that DCP2 activation by DCP1 occurs preferentially on the EDC4 scaffold, which may serve to couple DCP2 activation by DCP1 with 5'-to-3' mRNA degradation by XRN1 in human cells.

  4. Data show that Y14 interacts directly with the decapping factor Dcp2 and the 5' cap structure of mRNAs via different but overlapping domains.

  5. PNRC2 acts in synergy with Dcp1a to stimulate the decapping activity of Dcp2 by bridging the interaction between Dcp1a and Dcp2.

  6. Like Dcp2, Nudt16 also regulates the stability of a subset of mRNAs including a member of the motin family of proteins involved in angiogenesis.

  7. an mRNA decapping enzyme demonstrated to contain intrinsic decapping activity

  8. These data suggest that a human decapping complex containing decapping enzymes hDcp1a and hDcp2 may be recruited to mRNAs containing premature termination codons by the hUpf proteins.

  9. Human Dcp2 is a catalytically active mRNA decapping enzyme that localizes to the cytoplasm

  10. LSm1-7 proteins colocalize with DCP1,DCP2 and Xrn1 in cytoplasmic foci

  11. hDcp2 can specifically bind to and can regulate the stability of a subset of mRNAs

  12. These data support the novel notion of the association between Ro52 with hDCP2 protein in cytoplasmic p-bodies, playing a role in mRNA metabolism in response to cellular stimulation.

DCP2 Antigen Profile

Protein Summary

The protein encoded by this gene is a key component of an mRNA-decapping complex required for degradation of mRNAs, both in normal mRNA turnover, and in nonsense-mediated mRNA decay (NMD). It removes the 7-methyl guanine cap structure from mRNA, prior to its degradation from the 5' end. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene names and symbols associated with DCP2

  • mRNA-decapping enzyme 2 (CpipJ_CPIJ019463) antibody
  • mRNA-decapping enzyme 2 (PTRG_05936) antibody
  • mRNA-decapping enzyme 2 (dcp2) antibody
  • mRNA-decapping enzyme 2 (MCYG_05106) antibody
  • mRNA-decapping enzyme 2 (MGYG_07617) antibody
  • hypothetical protein (PGTG_03310) antibody
  • mRNA-decapping enzyme 2 (Tsp_04018) antibody
  • decapping mRNA 2 (dcp2) antibody
  • decapping mRNA 2 (DCP2) antibody
  • decapping mRNA 2 (Dcp2) antibody
  • 2410015D23Rik antibody
  • 5730537H01Rik antibody
  • AL118268 antibody
  • DDBDRAFT_0185453 antibody
  • DDBDRAFT_0252811 antibody
  • DDB_0185453 antibody
  • DDB_0252811 antibody
  • NUDT20 antibody
  • RGD1562909 antibody

Protein level used designations for DCP2

mRNA-decapping enzyme 2 , DCP2 decapping enzyme homolog , m7GpppN-mRNA hydrolase , hDpc , nudix (nucleoside diphosphate linked moiety X)-type motif 20

GENE ID SPECIES
6054129 Culex quinquefasciatus
6344191 Pyrenophora tritici-repentis Pt-1C-BFP
8624030 Dictyostelium discoideum AX4
9230993 Arthroderma otae CBS 113480
10025613 Arthroderma gypseum CBS 118893
10538062 Puccinia graminis f. sp. tritici CRL 75-36-700-3
10904275 Trichinella spiralis
100195938 Salmo salar
489086 Canis lupus familiaris
70640 Mus musculus
100127054 Pongo abelii
167227 Homo sapiens
291604 Rattus norvegicus
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