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Ligand-dependent coactivator of nuclear receptors.
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Human Polyclonal DCAF6 Primary Antibody for WB - ABIN442454
Chang, Tsao, Lin, Chen: NRIP, a novel calmodulin binding protein, activates calcineurin to dephosphorylate human papillomavirus E2 protein. in Journal of virology 2011
High IQWD1 expression is associated with breast cancer.
NRIP enhances HPV 16 gene expression via interaction with either GR or viral E2.
NRIP interacts with either androgen or glucocorticoid receptors
NRIP plays a feed-forward role enhancing androgen receptor (AR (show AR Antibodies))-driven NRIP promoter activity via NRIP forming a complex with AR to protect AR protein from proteasome degradation.
A survey results showed that ten cancer cases were revealed to express the NRIP in six malignancies, but not all of these specific tumor types consistently showed positive NRIP expression.
Ligand-dependent coactivator of nuclear receptors. Enhance transcriptional activity of the nuclear receptors NR3C1 and AR. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
DDB1- and CUL4-associated factor 6
, IQ motif and WD repeat-containing protein 1
, IQ motif and WD repeats 1
, androgen receptor complex-associated protein
, nuclear receptor interaction protein
, DDB1 and CUL4 associated factor 6
, Nuclear receptor interaction protein
, DDB1 and CUL4 associated factor 6 S homeolog