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DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. Additionally we are shipping DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 50 Antibodies (33) and DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 50 Proteins (4) and many more products for this protein.
Results provide evidence that DDX50 negatively regulates DENV-2 replication during the early stages of infection by inducing IFN-beta (show IFNB1 ELISA Kits) production.
Solution structure of the GUCT domain from human RNA helicase II/Gu beta reveals the RRM fold, but implausible RNA interactions.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box enzyme that may be involved in ribosomal RNA synthesis or processing. This gene and DDX21, also called RH-II/GuA, have similar genomic structures and are in tandem orientation on chromosome 10, suggesting that the two genes arose by gene duplication in evolution. This gene has pseudogenes on chromosomes 2, 3 and 4. Alternative splicing of this gene generates multiple transcript variants, but the full length nature of all the other variants but one has not been defined.
ATP-dependent RNA helicase DDX50
, DEAD box protein 50
, RNA helicase II/Gu beta
, malignant cell derived RNA helicase
, nucleolar protein GU2
, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 50
, DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
, DEAD (Asp-Glu-Ala-Asp) box polypeptide 21
, ATP-dependent RNA helicase DDX50-like
, DEAD-box helicase 50