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Critical regulator of cell growth under specific conditions. Additionally we are shipping DRG1 Antibodies (45) and DRG1 Kits (3) and many more products for this protein.
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DRG-1 plays an important role in melanoma cell growth and transformation, indicating that DRG1 may represent a novel target for CD4 (show CD4 Proteins)(+) T cell-mediated immunotherapy in melanoma.
Lerepo4 (show ZC3H15 Proteins) action leaves Drg1 affinity for nucleotides unaffected, feasibly favoring a switch I reorientation, mainly via the TGS (show LIN9 Proteins) domain.
Drg-1 is a candidate metastasis suppressor gene for prostate cancer and may serve as a useful prognostic marker.
our results strongly suggest functional involvement of the Drg-1 gene in suppressing the metastatic advancement of human breast cancer.
The tumor metastasis suppressor gene Drg-1 suppresses metastasis of prostate tumor cells by inhibiting the invasive ability of the cells via down-regulation of the expression of the ATF3 (show ATF3 Proteins) gene.
NDR1 interacts with TRAF3 and interferes with the association of TRAF3 and IL-17R, resulting in increased formation of the activation complex IL-17R-Act1, which is required for the downstream signaling and production of pro-inflammatory factors
NDR1 (show STK38 Proteins) kinase, activated by the Rap1 (show TERF2IP Proteins) signaling cascade through RAPL (show RASSF5 Proteins) and Mst1 (show MST1 Proteins)/Mst2 (show STK3 Proteins), associated with and recruited kindlin-3 (show FERMT3 Proteins) to the immunological synapses, which was required for high-affinity LFA-1 (show ITGAL Proteins)/ICAM-1 (show ICAM1 Proteins) binding.
Snell, GHKRO, and PAPPA (show PAPPA Proteins)-KO mice express high levels of two proteins involved in DNA repair, O-6-methylguanine-DNA methyltransferase (MGMT (show MGMT Proteins)) and N-myc downstream-regulated gene 1 (NDRG1 (show NDRG1 Proteins)).
NDRG1 deficiency attenuates the differentiation of macrophage lineage cells, suppressing bone remodeling and inflammatory angiogenesis. This study strongly suggests the crucial role of NDRG1 in differentiation process for macrophages.
Using double knockout of NDR1 (show STK38 Proteins) and 2 shows that NDRs acted downstream of MST1 (show MST1 Proteins) to mediate the egress of mature thymocytes from the thymus, as well as the interstitial migration of naive T cells within popliteal lymph nodes.
Ndrg1 (show NDRG1 Proteins) is phosphorylated and degraded by CD28 (show CD28 Proteins) signalling in a proteasome-dependent manner.
Ndr1 (show STK38 Proteins)/2-double null embryos show defects in somitogenesis and cardiac looping, which reveals their essential functions and shows that the NDR (show STK38 Proteins) kinases are critically required during the early phase of organogenesis
Rassf5 (show RASSF5 Proteins) and Ndr1 (show STK38 Proteins) or Ndr2 (show STK38L Proteins) kinases regulate neuronal polarity through Par3 (show F2RL2 Proteins) phosphorylation.
NDRG1 promotes fetal growth and regulates the metabolic response to intrauterine hypoxic injury in a sexually dichotomous manner
early growth response 1 (show EGR1 Proteins), a transcription factor that binds to the NDRG1 (show NDRG1 Proteins) promoter, was mediated in the NDRG1 (show NDRG1 Proteins) expression regulation by PKD2 (show PKD2 Proteins).
Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest.
developmentally regulated GTP binding protein 1
, developmentally-regulated GTP-binding protein 1
, developmentally-regulated GTP-binding protein 1-like
, Gallus gallus drg1 partial fragment
, developmentally regulated GTP-binding protein 1
, neural precursor cell expressed developmentally down-regulated protein 3
, neural precursor cell expressed, developmentally down-regulated 3
, GTP-binding protein
, GTP-binding protein DRG
, N-myc downstream regulated 1
, N-myc downstream-regulated gene 1 protein
, protein NDRG1
, protein Ndr1