anti-Dihydropyrimidinase (DPYS) Antibodies

Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Additionally we are shipping DPYS Kits (11) and DPYS Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DPYS 1807 Q14117
DPYS 64705 Q9EQF5
DPYS 65135 Q63150
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Top anti-DPYS Antibodies at antibodies-online.com

Showing 10 out of 103 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-DPYS Antibody Titration:  2.5ug/ml  Positive Control:  Transfected 293T 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-DPYS Antibody Titration:  1.25ug/ml  Positive Control:  Transfected 293T 100 μL Log in to see 2 to 3 Days
$229.00
Details
Bat Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Bat Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Human Rabbit Un-conjugated IHC (p), WB DPYS Antibody (C-term) (ABIN657357) western blot analysis in Jurkat,K562 cell line lysates (35 µg/lane). This demonstrates the DPYS antibody detected the DPYS protein (arrow). 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: DPYS Antibody [NBP1-85224] - Staining of human cell line A-431 shows positivity in vesicles & centrosome. Immunohistochemistry-Paraffin: DPYS Antibody [NBP1-85224] - Staining of human kidney shows strong cytoplasmic positivity in cells of tubules. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated WB Western Blot: DPYS Antibody [NBP1-55121] - Titration: 2.5ug/ml Positive Control: Transfected 293T. 100 μL Log in to see 8 to 11 Days
$444.19
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged DPYS is approximately 0.1ng/ml as a capture antibody. 100 μg Log in to see 8 to 11 Days
$461.00
Details
Human Rabbit Un-conjugated WB DPYS antibody used at 1.25 ug/ml to detect target protein. 100 μg Log in to see 2 to 3 Days
$388.93
Details
Human Rabbit Un-conjugated WB DPYS antibody used at 2.5 ug/ml to detect target protein. 100 μg Log in to see 2 to 3 Days
$388.93
Details

Top referenced anti-DPYS Antibodies

  1. Cow (Bovine) Polyclonal DPYS Primary Antibody for WB - ABIN2776832 : Thomas, Chen, Lin, Tomlinson, Lam, Liu, Yeung, Chan, Wong: Middle cerebral artery stenosis increased the risk of vascular disease mortality among type 2 diabetic patients. in Cerebrovascular diseases (Basel, Switzerland) 2008 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal DPYS Primary Antibody for WB - ABIN2779197 : Kunicka, Prochazka, Krus, Bendova, Protivova, Susova, Hlavac, Liska, Novak, Schneiderova, Pitule, Bruha, Vycital, Vodicka, Soucek: Molecular profile of 5-fluorouracil pathway genes in colorectal carcinoma. in BMC cancer 2016 (PubMed)

  3. Cow (Bovine) Polyclonal DPYS Primary Antibody for WB - ABIN2776833 : Thomas, Ezzeldin, Guarcello, Mattison, Fridley, Diasio: Genetic regulation of beta-ureidopropionase and its possible implication in altered uracil catabolism. in Pharmacogenetics and genomics 2008 (PubMed)
    Show all 2 Pubmed References

More Antibodies against DPYS Interaction Partners

Human Dihydropyrimidinase (DPYS) interaction partners

  1. 4 newly identified DHP (show DPYD Antibodies) deficient patients presented with strongly elevated levels of 5,6-dihydrouracil and 5,6-dihydrothymine in urine and a highly variable clinical presentation, ranging from asymptomatic to infantile spasm and reduced white matter and brain atrophy. Analysis of the DHP (show DPYD Antibodies) gene (DPYS) showed the presence of 8 variants including 4 novel/rare missense variants and one novel deletion.

  2. Two unrelated pediatric DPYS deficiency cases are being described as compound heterozygotes for a novel intronic mutation c.1443+5G>A in intron 8 and a previously described missense mutation c.1001A>G (p.Q334R) in exon 6.

  3. Stepwise Cox regression modelling suggested that the methylation of genes HSPB1, CCND2 and DPYS contributed objective prognostic information to Gleason score and PSA with respect to prostate cancer-related death.

  4. The p.S379R and p.L7V mutations were likely to cause structural destabilization and protein misfolding. Four mutations were identified in multiple unrelated DHP (show DPYD Antibodies) patients, indicating that DHP (show DPYD Antibodies) deficiency may be more common than anticipated.

  5. Results indicate that missense and nonsense variants in DPYS are infrequent, however, the development of serious primarily gastrointestinal toxicity could be influenced by non-coding DPYS sequence variants c.-1T>C and IVS1-58T>C.

  6. clinical, biochemical & genetic findings of two newly identified patients with a complete DHP (show DPYD Antibodies) deficiency; both patients were compound heterozygous for the missense mutation 1078T>C (W360R) in exon 6 and a novel missense mutation 1235G>T (R412M) in exon 7

  7. data presented in this study offers evidence for the possible genetic regulation of the DPYS gene and its possible influence on uracil catabolic pathway

DPYS Antigen Profile

Protein Summary

Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.

Gene names and symbols associated with DPYS

  • dihydropyrimidinase (DPYS) antibody
  • dihydropyrimidinase (Dpys) antibody
  • dihydropyrimidinase (Jann_1488) antibody
  • dihydropyrimidinase (hydA) antibody
  • dihydropyrimidinase (h16_A3075) antibody
  • dihydropyrimidinase (Veis_0725) antibody
  • dihydropyrimidinase (AZC_1966) antibody
  • dihydropyrimidinase (M446_2543) antibody
  • dihydropyrimidinase (RSKD131_3628) antibody
  • dihydropyrimidinase (Vapar_5601) antibody
  • dihydropyrimidinase (Rleg_5687) antibody
  • dihydropyrimidinase (LOC9307588) antibody
  • dihydropyrimidinase (EIO_3239) antibody
  • dihydropyrimidinase (blr3333) antibody
  • dihydropyrimidinase (BAV0676) antibody
  • dihydropyrimidinase (hyuA) antibody
  • dihydropyrimidinase (CtCNB1_2936) antibody
  • dihydropyrimidinase (dpyS) antibody
  • dihydropyrimidinase (Pat9b_1914) antibody
  • dihydropyrimidinase (dpys) antibody
  • dihydropyrimidinase L homeolog (dpys.L) antibody
  • 1200017I10Rik antibody
  • 1300004I01Rik antibody
  • dhp antibody
  • DHPase antibody

Protein level used designations for DPYS

dihydropyrimidine amidohydrolase , hydantoinase , DHP , DHPase , dihydropyrimidinase

GENE ID SPECIES
1807 Homo sapiens
64705 Mus musculus
65135 Rattus norvegicus
3933935 Jannaschia sp. CCS1
4010267 Burkholderia xenovorans LB400
4249970 Ralstonia eutropha H16
4690821 Verminephrobacter eiseniae EF01-2
5690979 Azorhizobium caulinodans ORS 571
6132533 Methylobacterium sp. 4-46
7353624 Rhodobacter sphaeroides KD131
7975213 Variovorax paradoxus S110
8016650 Rhizobium leguminosarum bv. trifolii WSM1325
9307588 Arabidopsis lyrata subsp. lyrata
9886600 Ketogulonicigenium vulgare Y25
1050490 Bradyrhizobium diazoefficiens USDA 110
4196355 Roseobacter denitrificans OCh 114
6264902 Bordetella avium 197N
6453799 Cupriavidus taiwanensis LMG 19424
8564745 Comamonas testosteroni CNB-2
8791932 Azospirillum sp. B510
10069347 Pantoea sp. At-9b
100144569 Danio rerio
495311 Xenopus laevis
420266 Gallus gallus
509241 Bos taurus
100856067 Canis lupus familiaris
100717795 Cavia porcellus
Selected quality suppliers for anti-DPYS (DPYS) Antibodies
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