Discs, Large Homolog 3 (Drosophila) (DLG3) ELISA Kits

DLG3 encodes a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction. Additionally we are shipping DLG3 Antibodies (104) and DLG3 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
DLG3 1741 Q92796
Anti-Mouse DLG3 DLG3 53310 P70175
Anti-Rat DLG3 DLG3 58948 Q62936
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top DLG3 ELISA Kits at antibodies-online.com

Showing 1 out of 2 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.115 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Log in to see 13 to 16 Days
$589.47
Details

More ELISA Kits for DLG3 Interaction Partners

Human Discs, Large Homolog 3 (Drosophila) (DLG3) interaction partners

  1. This family broadens the mutational and phenotypical spectrum of DLG3-associated non-syndromic X-linked intellectual disability and demonstrates that heterozygous female mutation carriers can be as severely affected as males.

  2. Data suggest that 300-residue C-terminal domain of PLCB3 promotes adsorption to phospholipid monolayer/membrane bilayer and is required for spatial organization/adsorption of PLCB3 on membrane surface; defects in phosphatidylinositol 4,5-bisphosphate (PIP2) hydrolysis alter monolayer adsorption, thus, suggesting role of active site in this process; PLCB3 is preferentially adsorbed to region of bilayer enriched with PIP2.

  3. These results indicate that the mechanism by which Galphaq (show GNAQ ELISA Kits) and PLC (show HSPG2 ELISA Kits)-beta3 mutually regulate each other is far more complex than a simple, two-state allosteric model and instead is probably kinetically determined.

  4. Following the critical period NMDA receptor function was unaffected by loss of SAP102 but there was a reduction in the divergence of TC connectivity. These data suggest that changes in synaptic function early in development caused by mutations in SAP102 result in changes in network connectivity later in life.

  5. Insertion of a guanine into the DLG3 5' UTR (show UTS2R ELISA Kits), 7 bp upstream of the start codon, down regulated DLG3 protein levels. This non-coding variant segregates with X-linked intellectual disability in a large family.

  6. We propose that unliganded PLC (show HSPG2 ELISA Kits)-beta exists in equilibrium between a closed conformation observed in crystal structures and an open conformation where the PH domain moves away from the EF hands. Therefore, intrinsic movement of the PH domain in PLC (show HSPG2 ELISA Kits)-beta modulates Gbetagamma access to its binding site.

  7. the MCP1 (show CCL2 ELISA Kits)-induced cortactin (show CTTN ELISA Kits) phosphorylation is dependent on PLCb3 (show PLCB3 ELISA Kits)-mediated PKC activation, and siRNA-mediated down-regulation of either of these molecules prevents cortactin (show CTTN ELISA Kits) interaction with WAVE2 (show WASF2 ELISA Kits)

  8. Gnb isoforms control a signaling pathway comprising Rac1, Plcbeta2, and Plcbeta3 leading to LFA-1 (show ITGAL ELISA Kits) activation and neutrophil arrest in vivo

  9. Trans-homophilic interaction of CADM1 (show CADM1 ELISA Kits) activates PI3K (show PIK3CA ELISA Kits) by forming a complex with MAGuK-family proteins MPP3 (show MPP3 ELISA Kits) and Dlg (show DLG4 ELISA Kits).

  10. miR (show MLXIP ELISA Kits)-1246 might play a role in neurological pathogenesis of human enterovirus 71 by regulating DLG3 gene in infected cells.

Mouse (Murine) Discs, Large Homolog 3 (Drosophila) (DLG3) interaction partners

  1. Following the critical period NMDA receptor function was unaffected by loss of SAP102 but there was a reduction in the divergence of TC connectivity. These data suggest that changes in synaptic function early in development caused by mutations in SAP102 result in changes in network connectivity later in life.

  2. our current study identified a functional interplay between PSD-95 (show DLG4 ELISA Kits) and synapse-associated protein 102 (SAP102) to regulate synaptic AMPA (show GRIA3 ELISA Kits) receptors

  3. SAP102 has a fundamental role in trafficking the NMDA receptor complex to the synaptic sites.

  4. The Dlg3 have functions in complex cognitive processes.

  5. Synapse associated protein 102 (SAP102) binds the C-terminal part of the scaffolding protein neurobeachin (show NBEA ELISA Kits).

  6. Dlg3 exerts a distinct function by recruiting the ubiquitin ligases Nedd4 and Nedd4-2 through its PPxY motifs. These interactions are required for Dlg3 monoubiquitination, apical membrane recruitment, and tight junction consolidation.

  7. Membrane-associated guanylate kinase (show GUK1 ELISA Kits) homolog SAP102 is a central organizers of the postsynaptic density at excitatory synapses on pyramidal neurons.

  8. SAP102 interacts with the PDZ-binding domain of Sec8, a member of the exocyst complex. nteractions between the two proteins are involved in the delivery of N-methyl-D-aspartate receptors to the cell surface in heterologous cells and neurons.

  9. SAP102 was required for normal spatial learning. Loss of SAP102 results in changes in spatial strategy usage. Altered long term potentiation and spike-timing-dependent plasticity in SAP102 mutants. Couples NMDA receptors to MAPK/ERK (show MAPK1 ELISA Kits) pathway.

  10. Results describe E-dlg (show DLG4 ELISA Kits), a mouse homologue of the Drosophila discs large (show DLG4 ELISA Kits) tumor suppressor (Dlg (show DLG4 ELISA Kits), also known as SAP97), that binds preferentially to SAP102.

DLG3 Antigen Profile

Antigen Summary

This gene encodes a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with DLG3

  • discs large MAGUK scaffold protein 3 (DLG3) antibody
  • phospholipase C beta 3 (PLCB3) antibody
  • discs, large homolog 3 (Drosophila) (dlg3) antibody
  • discs, large homolog 3 (Drosophila) (Dlg3) antibody
  • discs large MAGUK scaffold protein 3 (Dlg3) antibody
  • Dlgh3 antibody
  • fa66c08 antibody
  • fa66e02 antibody
  • fd02c12 antibody
  • fu95c12 antibody
  • im:7138640 antibody
  • mKIAA1232 antibody
  • MPP3 antibody
  • MRX antibody
  • MRX90 antibody
  • NEDLG antibody
  • SAP102 antibody
  • si:ch211-276g21.1 antibody
  • wu:fa66c08 antibody
  • wu:fa66e02 antibody
  • wu:fd02c12 antibody
  • wu:fu95c12 antibody
  • XLMR antibody

Protein level used designations for DLG3

disks large homolog 3 , neuroendocrine-DLG , synapse-associated protein 102 , 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 , PLC beta 3 , PLC-beta-3 , phosphoinositide phospholipase C-beta-3 , SAP-102 , discs large homolog 3 , discs, large homolog 3 (neuroendocrine-dlg, Drosophila) , membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) , PSD-95/SAP90-related protein 1 , SAP102

GENE ID SPECIES
1741 Homo sapiens
5331 Homo sapiens
564081 Danio rerio
53310 Mus musculus
428706 Gallus gallus
491942 Canis lupus familiaris
100516124 Sus scrofa
509882 Bos taurus
58948 Rattus norvegicus
100732206 Cavia porcellus
Selected quality suppliers for DLG3 (DLG3) ELISA Kits
Did you look for something else?