Docking Protein 4 Proteins (DOK4)

DOK proteins are enzymatically inert adaptor or scaffolding proteins.

list all proteins Gene Name GeneID UniProt
Human DOK4 DOK4 55715 Q8TEW6
Mouse DOK4 DOK4 114255 Q99KE3
Rat DOK4 DOK4 361364  
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Top DOK4 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,960.83
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,960.83
Details
Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$338.33
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Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Log in to see Available
$284.90
Details
Escherichia coli (E. coli) Human His tag   100 μg Log in to see 13 to 16 Days
$400.00
Details
Yeast Orang-Utan His tag   1 mg Log in to see 60 to 71 Days
$2,918.67
Details

More Proteins for Docking Protein 4 (DOK4) Interaction Partners

Human Docking Protein 4 (DOK4) interaction partners

  1. the current study have explored in more detail the structure and function of the Dok-4 PTB (show PTBP1 Proteins) domain.

  2. DOK4 expression in human T cells has been demonstrated, and its genomic structure has been predicted.

  3. IRS5/DOK4 and IRS6/DOK5 (show DOK5 Proteins) represent two new signaling proteins with potential roles in insulin (show INS Proteins) and IGF-1 (show IGF1 Proteins) action

  4. Results suggest that Dok-4, through activation of the Rap1-ERK1/2 pathway, regulates GDNF-mediated neurite outgrowth during neuronal development.

  5. IRS-5 (DOK4) is significantly upregulated in 90% of examined clear cell RCCs. Studies on this gene has shown that it is regulated through chromatin remodeling in kidney cells

  6. Epigenetic regulation of DOK4 expression is associated with non-small-cell lung cancer.

  7. Dok-4 represents a novel negative regulator of T cells

Mouse (Murine) Docking Protein 4 (DOK4) interaction partners

  1. Dok-4 can target Elk-4 (show ELK4 Proteins) activity through multiple mechanisms, including binding of the transactivation domain, nuclear exclusion and protein destabilization.

  2. the current study have explored in more detail the structure and function of the Dok-4 PTB (show PTBP1 Proteins) domain.

  3. Dok-4 is a constitutively membrane-localized adapter molecule that may function as an inhibitor of tyrosine kinase (show TYRO3 Proteins) signaling in epithelial cells.

DOK4 Protein Profile

Protein Summary

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.

Gene names and symbols associated with Docking Protein 4 Proteins (DOK4)

  • docking protein 4 (DOK4)
  • docking protein 4 (Dok4)
  • DOK4 protein

Protein level used designations for Docking Protein 4 Proteins (DOK4)

IRS-5 , IRS5 , downstream of tyrosine kinase 4 , insulin receptor substrate 5 , docking protein 4

GENE ID SPECIES
100052258 Equus caballus
55715 Homo sapiens
114255 Mus musculus
361364 Rattus norvegicus
430610 Gallus gallus
487264 Canis lupus familiaris
100620637 Sus scrofa
100172743 Pongo abelii
618756 Bos taurus
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