anti-Doublecortin (DCX) Antibodies

DCX encodes a member of the doublecortin family. Additionally we are shipping Doublecortin Kits (47) and Doublecortin Proteins (15) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DCX 1641 O43602
DCX 13193 O88809
DCX 84394  
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Top anti-Doublecortin Antibodies at

Showing 10 out of 202 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-DCX Antibody Titration:  0.2-1 ug/ml  Positive Control:  293T cell lysate 100 μL Log in to see 2 to 3 Days
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-DCX Antibody Titration:  0.2-1 ug/ml  Positive Control:  HepG2 cell lysate Sample Type :  Mouse spinal cord  Primary Antibody Dilution :  1:300  Secondary Antibody :  Anti-rabbit-Alexa 594  Secondary Antibody Dilution :  1:500  Color/Signal Descriptions :  Red: DCX Blue:DAPI  Gene Name :  DCX  Submitted by :  Anonymous 100 μL Log in to see 2 to 3 Days
Human Mouse Un-conjugated IF, WB Western Blot analysis of DCX expression in transfected 293T cell line by DCX monoclonal antibody (M01), clone 1G12. Lane 1: DCX transfected lysate(41.4 KDa). Lane 2: Non-transfected lysate. Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (65.34 KDa) . Dilution: 1:500~1000 100 μg Log in to see 8 to 11 Days
Mouse Rabbit Un-conjugated WB Western blot analysis of Doublecortin expression in rat brain extract ( Lane 1) and mouse brain extract ( Lane 2). Doublecortin at 40KD was detected using rabbit anti- Doublecortin Antigen Affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002). 100 μg Log in to see 4 to 6 Days
Human Mouse Un-conjugated ELISA, FACS, IF/ICC, IHC, WB 100 μg Log in to see 11 to 16 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from RAW264.7 cells, using Doublecortin (Ab-297) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from Jurkat cells, using Doublecortin (Ab-376) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
Human Mouse Un-conjugated ELISA, FACS, ICC, IHC, WB Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (50 ng);Red line: Antigen (100 ng); Dilution: 1/10000 Figure 1: Western blot analysis using DCX mAb against human DCX recombinant protein. (Expected MW is 34.1 kDa)  Dilution: 1/500 - 1/2000 100 μL Log in to see 8 to 11 Days
Mouse Goat Un-conjugated ELISA, WB Antibody (0.01µg/ml) staining of Mouse fetal Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Antibody (2µg/ml) staining of paraffin embedded Human Cerebellum. Microwaved antigen retrieval with citrate buffer pH 6, HRP-staining. 100 μg Log in to see 6 to 7 Days
Mouse Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days

DCX Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Doublecortin Antibodies

  1. Human Monoclonal Doublecortin Primary Antibody for ICC, FACS - ABIN969513 : Evangelisti, Florian, Massimi, Dominici, Giannini, Galardi, Buè, Massalini, McDowell, Messi, Gulino, Farace, Ciafrè: MiR-128 up-regulation inhibits Reelin and DCX expression and reduces neuroblastoma cell motility and invasiveness. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009 (PubMed)

  2. Human Monoclonal Doublecortin Primary Antibody for IF, ELISA - ABIN560579 : Jiang, Brackeva, Stangé, Verhaeghen, Costa, Couillard-Després, Rotheneichner, Aigner, Van Schravendijk, Pipeleers, Ling, Gorus, Martens: LC-MS/MS identification of doublecortin as abundant beta cell-selective protein discharged by damaged beta cells in vitro. in Journal of proteomics 2013 (PubMed)

  3. Mouse (Murine) Polyclonal Doublecortin Primary Antibody for ELISA, WB - ABIN4305985 : Klempin, Kronenberg, Cheung, Kettenmann, Kempermann: Properties of doublecortin-(DCX)-expressing cells in the piriform cortex compared to the neurogenic dentate gyrus of adult mice. in PLoS ONE 2011 (PubMed)

More Antibodies against Doublecortin Interaction Partners

Human Doublecortin (DCX) interaction partners

  1. Age-associated expression of the proliferation and immature neuron markers MKI67 (show MKI67 Antibodies) and DCX, respectively, was unrelated, suggesting that neurogenesis-associated processes are independently altered at these points in the development from stem cell to neuron.

  2. this suggests that the microtubule-interacting doublecortin domain observed in cryo-electron micrographs is the C-terminal domain rather than the N-terminal one.

  3. From this family, we conclude that a DCX mutation causes a pleiotropic phenotype in the female even if X chromosome inactivation pattern is not skewed, and the novel missense mutation in DCX produced relatively mild dysfunction of the doublecortin protein.

  4. We identified a novel DCX mutation c.785A > G, p.Asp262Gly in a family with X-linked lissencephaly and subcortical band heterotopia

  5. In high-risk metastatic Neuroblastoma (show ARHGEF16 Antibodies), TH and DCX mRNA quantification could be used for the assessment of response to treatment and for early detection of progressive disease or relapses.

  6. Results point to a critical role of doublecortin in the formation of the neuromuscular junctions.

  7. DCX-positive cells occur in a wide range of hypothalamic nuclei in humans, mice and sheep.

  8. human DCX protein was expressed in human adipose stem cells, collagen II was decreased while aggrecan (show ACAN Antibodies), matrilin 2 (show MATN2 Antibodies), and GDF5 (show GDF5 Antibodies) were increased during the 14-day pellet culture.

  9. We propose that DCDC2 (show DCDC2 Antibodies) is a tumor suppressor gene of HCC (show FAM126A Antibodies).

  10. in utero doublecortin knockdown, but not knockout, shows a neocortical neuronal migration phenotype.

Mouse (Murine) Doublecortin (DCX) interaction partners

  1. Authors found that 14-3-3epsilon binds to the microtubule binding protein, doublecortin (Dcx) in a phosphorylation dependent manner and that this binding increases the Dcx protein levels in the cell by interrupting ubiquitin based degradation.

  2. MEIS2 (show MEIS2 Antibodies) associates with chromatin-bound PBX1 (show PBX1 Antibodies), recruits PARP1/ARTD1 (show PARP1 Antibodies), and initiates PARP1 (show PARP1 Antibodies)-mediated eviction of H1 from the chromatin fiber.

  3. The regulation axis from microRNA-128-3p to doublecortin is critical for hippocampus-related contextual learning not only in wild type, but also in mice infused with Abeta (show APP Antibodies)-42.

  4. Findings demonstrate the direct requirement of ADAM10 (show ADAM10 Antibodies) in cortical radial migration and reveal the underlying mechanism by linking ADAM10 (show ADAM10 Antibodies)-initiated regulated intramembrane proteolysis of Notch (show NOTCH1 Antibodies) to the regulation of microtubule cytoskeleton through transcriptional control of Dcx expression

  5. Dcx is a new marker for the Pax7 (show PAX7 Antibodies)(+)MyoD (show MYOD1 Antibodies)(-) subpopulation, which contributes to myofiber maturation during muscle regeneration.

  6. DCX-positive cells resembling immature and developing neurons were found in mice and sheep and human hypothalamus.

  7. we showed that miR (show MLXIP Antibodies)-29a directly regulated its target protein Doublecortin (DCX) expression, which further modulated axon branching in primary culture.

  8. Cdk5 (show CDK5 Antibodies) and its substrates, Dcx and p27kip1 (show CDKN1B Antibodies), regulate cytoplasmic dilation formation and nuclear elongation in migrating neurons.

  9. Doublecortin knockout mice show lamination defects of the hippocampal pyramidal cell layer largely restricted to the CA3 (show CA3 Antibodies) region.

  10. Dcx protein- and mRNA-levels reflected changes in neurogenesis

Doublecortin (DCX) Antigen Profile

Protein Summary

This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia ('double cortex' syndrome) in females and lissencephaly ('smooth brain' syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Doublecortin (DCX) Antibodies

  • doublecortin (DCX) antibody
  • doublecortin (Dcx) antibody
  • 18C15.5 antibody
  • DBCN antibody
  • Dbct antibody
  • DC antibody
  • DCX antibody
  • LISX antibody
  • SCLH antibody
  • XLIS antibody

Protein level used designations for anti-Doublecortin (DCX) Antibodies

doublecortex; lissencephaly, X-linked (doublecortin) , doublecortin , doublecortex , doublin , lis-X , lissencephalin-X , neuronal migration protein doublecortin , lissencephaly, X-linked (doublecortin)

100058909 Equus caballus
494212 Felis catus
473733 Pan troglodytes
752002 Taeniopygia guttata
1641 Homo sapiens
13193 Mus musculus
84394 Rattus norvegicus
374242 Gallus gallus
787968 Bos taurus
612950 Canis lupus familiaris
100713827 Cavia porcellus
101109861 Ovis aries
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