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DCX encodes a member of the doublecortin family. Additionally we are shipping Doublecortin Kits (41) and Doublecortin Proteins (12) and many more products for this protein.
Showing 10 out of 166 products:
Mouse (Murine) Monoclonal Doublecortin Primary Antibody for IF, WB - ABIN968637
des Portes, Pinard, Billuart, Vinet, Koulakoff, Carrié, Gelot, Dupuis, Motte, Berwald-Netter, Catala, Kahn, Beldjord, Chelly: A novel CNS gene required for neuronal migration and involved in X-linked subcortical laminar heterotopia and lissencephaly syndrome. in Cell 1998
Show all 3 Pubmed References
Human Monoclonal Doublecortin Primary Antibody for ICC, FACS - ABIN969513
Evangelisti, Florian, Massimi, Dominici, Giannini, Galardi, Buè, Massalini, McDowell, Messi, Gulino, Farace, Ciafrè: MiR-128 up-regulation inhibits Reelin and DCX expression and reduces neuroblastoma cell motility and invasiveness. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009
Human Monoclonal Doublecortin Primary Antibody for IF, ELISA - ABIN560579
Jiang, Brackeva, Stangé, Verhaeghen, Costa, Couillard-Després, Rotheneichner, Aigner, Van Schravendijk, Pipeleers, Ling, Gorus, Martens: LC-MS/MS identification of doublecortin as abundant beta cell-selective protein discharged by damaged beta cells in vitro. in Journal of proteomics 2013
Mouse (Murine) Polyclonal Doublecortin Primary Antibody for ELISA, WB - ABIN4305985
Klempin, Kronenberg, Cheung, Kettenmann, Kempermann: Properties of doublecortin-(DCX)-expressing cells in the piriform cortex compared to the neurogenic dentate gyrus of adult mice. in PLoS ONE 2011
This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia ('double cortex' syndrome) in females and lissencephaly ('smooth brain' syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene.
doublecortex; lissencephaly, X-linked (doublecortin)
, neuronal migration protein doublecortin
, lissencephaly, X-linked (doublecortin)