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The protein encoded by DUSP15 belongs to the non-receptor class of the protein-tyrosine phosphatase family. Additionally we are shipping DUSP15 Antibodies (64) and and many more products for this protein.
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The results showed that dual specificity phosphatase 15 (DUSP15) rs3746599 was significantly associated with autism under allelic, additive and dominant models,The findings initially suggest that DUSP15 might be a susceptibility gene for autism in Chinese Han population.
Dusp15/VHY is a key regulator of oligodendrocyte differentiation, and PDGFR-beta and SNX6 are novel and specific Dusp15 substrates.
VHY is a new member of a subgroup of myristoylated VH1-like small dual specificity phosphatases
crystal structure of catalytic domain
Dusp15 is necessary for full activation of Erk 1/2 phosphorylation in Schwann cells.
The protein encoded by this gene belongs to the non-receptor class of the protein-tyrosine phosphatase family. The encoded protein has both protein-tyrosine phophatase activity and serine/threonine-specific phosphatase activity, and therefore is known as a dual specificity phosphatase. Three transcript variants encoding two different isoforms have been found for this gene.
dual specificity phosphatase 15 , VH1-related member Y , dual specificity phosphatase-like 15 , dual specificity protein phosphatase 15 , vaccinia virus VH1-related dual-specific protein phosphatase Y , dual specificity protein phosphatase T-DSP10